硫酸软骨素寡糖及其衍生物调节Aβ细胞毒性及Tau蛋白磷酸化的分子机制研究

81671395
2016
H1901.衰老机制与调控
肖玉良
面上项目
教授
山东第一医科大学
57万元
tau蛋白;阿尔兹海默症;抗炎;β-淀粉样蛋白;硫酸软骨素寡糖
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 一种CD44靶向硫酸软骨素-阿霉素缀合物及其PLGA混合胶束 专利 肖玉良;孙保亮;李玉琴;陈娜娜;刘平;高飞
2 硫酸软骨素锂及其制备方法和应用 专利 肖玉良;朱良珍;高飞;刘平;姬东升;陈娜娜
3 Dual-Target Inhibitors Based on HDACs: Novel Antitumor Agents for Cancer Therapy 期刊论文 Tingting Liu;Yichao Wan;Yuliang Xiao;Chengcai Xia;Guiyun Duan
4 Preparation, characterisation and in vitro and in vivo evaluation of CD44-targeted chondroitin sulphate-conjugated doxorubicin PLGA nanoparticles 期刊论文 Liu Ping;Chen Nana;Yan Lei;Gao Fei;Ji Dongsheng;Zhang Shijiao;Zhang Litao;Li Yuqin;Xiao Yuliang
5 硫酸软骨素纳米硒在制备治疗认知功能衰退相关神经系统疾病的药物中的应用 专利 肖玉良;徐巍;姬东升;高飞;刘平;李德龙;张思涛
6 6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment partially via suppressing astrocyte overactivation 期刊论文 Feng Zhang;Ji Guo Zhang;Wei Yang;Pu Xu;Yu Liang Xiao;Han Ting Zhang
7 一种新型的大鼠血浆中阿霉素含量测定方法 期刊论文 高飞;姬东生;刘平;陈娜娜;张梦潇;赵静;肖玉良
8 Protective effects of chondroitin sulphate nano-selenium on a mouse model of Alzheimer's disease 期刊论文 Ji Dongsheng;Wu Xiaming;Li Delong;Liu Ping;Zhang Sitao;Gao Debo;Gao Fei;Zhang Mengxiao;Xiao Yuliang
9 Small-molecule inhibitors of breast cancer-related targets: Potential therapeutic agents for breast cancer 期刊论文 Tingting Liu;Shubin Song;Xu Wang;Jifu Hao
10 Preparation and in vitro evaluation of multi-target-directed selenium-chondroitin sulfate nanoparticles in protecting against the Alzheimer's disease 期刊论文 Gao Fei;Zhao Jing;Liu Ping;Ji Dongsheng;Zhang Litao;Zhang Mengxiao;Li Yuqin;Xiao Yuliang
11 Synthesis and Biological Evaluation of Pyrano[2,3-f]chromene-4,8-dione Derivatives as Potential Anticancer Agents 期刊论文 Li Hongshuang;Wu Xiaming;Zhang Ruize;Hao Liqiang;Duan Guiyun;Xiao Yuliang;Xia Chengcai;Li Furong;You Guirong;Han Junfen
12 一种硫酸软骨素纳米硒的制备方法及其在制备抑制tau蛋白过度磷酸化药物中的应用 专利 肖玉良;孙保亮;王春晓;姬东生;高飞;刘平
13 Single and dual target inhibitors based on Bcl-2: Promising anti-tumor agents for cancer therapy 期刊论文 Tingting Liu;Zhongyu Wu;Yujing He;Yuliang Xiao;Chengcai Xia
14 硫酸软骨素纳米硒的制备及其多靶向抗阿尔兹海默症的活性研究 奖励 高飞;姬东生;刘平
15 Investigation of the Interaction Mechanism between Salbutamol and Human Serum Albumin by Multispectroscopic and Molecular Docking 期刊论文 Zhao Ting;Liu Zihui;Niu Jingmei;Lv Baoxing;Xiao Yuliang;Li Yuqin
16 Dual-target inhibitors based on BRD4: Novel therapeutic approaches for cancer 期刊论文 Sitao Zhang;Yanzhao Chen;Chengsen Tian;Yujing He;Zeru Tian;Yichao Wan;Tingting Liu
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享