基于网络模型的癌症相关模式挖掘理论与方法

61532014
2015
F0213.生物信息计算与数字健康
高琳
重点项目
教授
西安电子科技大学
290万元
数据集成;疾病模式;生物分子网络;动态分析;算法
2016-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A comprehensive overview and evaluation of circular RNA detection tools 期刊论文 Zeng Xiangxiang;Lin Wei;Guo Maozu;Zou Quan
2 Systematic tracking of coordinated differential network motifs identifies novel disease-related genes by integrating multiple data 期刊论文 Shi Kai;Gao Lin;Wang Bingbo
3 Inference of cellular level signaling networks using single-cell gene expression data in C. elegans reveals mechanisms of cell fate specification 期刊论文 Xiaotai Huang;Yuan Zhu
4 An improved K-medoids algorithm based on step increasing and optimizing medoids 期刊论文 Yu Donghua;Liu Guojun;Guo Maozu;Liu Xiaoyan
5 Integrating phenotypic features and tissue-specific information to prioritize disease genes 期刊论文 Deng Yue;Gao Lin;Guo Xingli;Wang Bingbo
6 Predicting MiRNA-Disease Association by Latent Feature Extraction with Positive Samples. 期刊论文 Che Kai;Guo Maozu;Wang Chunyu;Liu Xiaoyan;Chen Xi
7 miES: predicting the essentiality of miRNAs with machine learning and sequence features. 期刊论文 Song Fei;Cui Chunmei;Gao Lin;Cui Qinghua
8 Network-Based Method for Inferring Cancer Progression at the Pathway Level from Cross-Sectional Mutation Data 期刊论文 Wu Hao;Gao Lin;Kasabov Nikola K
9 Exploring triad-rich substructures by graph-theoretic characterizations in complex networks 期刊论文 Jia Songwei;Gao Lin;Gao Yong;Nastos James;Wen Xiao;Zhang Xindong;Wang Haiyang
10 Prediction of Novel Drugs for Hepatocellular Carcinoma Based on Multi-Source Random Walk 期刊论文 Yu Liang;Su Ruidan;Wang Bingbo;Zhang Long;Zou Yapeng;Zhang Jing;Gao Lin
11 Dynamic community detection based on network structural perturbation and topological similarity 期刊论文 Wang Peizhuo;Gao Lin;Ma Xiaoke
12 复杂疾病相关模式发现理论与方法研究 奖励 高琳;鱼亮;王炳波;郭杏莉;贾松卫;黄晓太
13 Identification of Pan-Cancer Prognostic Biomarkers Through Integration of Multi-Omics Data 期刊论文 Ning Zhao;Maozu Guo
14 Detection of driver pathways using mutated gene network in cancer 期刊论文 Li Feng;Gao Lin;Ma Xiaoke;Yang Xiaofei
15 Identifying Cancer Specific Driver Modules Using a Network-Based Method 期刊论文 Li Feng;Gao Lin;Wang Peizhuo;Hu Yuxuan
16 Identification and prioritization of differentially expressed genes for time-series gene expression data 期刊论文 Xing Linlin;Guo Maozu;Liu Xiaoyan;Wang Chunyu
17 A Cancer Gene Module Mining Method Based on Bio-Network of Multi-Omics Gene Groups 期刊论文 Chunyu Wang;Ning Zhao;Kai Sun
18 Drug repositioning based on triangularly balanced structure for tissue-specific diseases in incomplete interactome 期刊论文 Liang Yu;Jin Zhao;Lin Gao
19 Identify bilayer modules via pseudo-3D clustering: applications to miRNA-gene bilayer networks 期刊论文 Xu Yungang;Guo Maozu;Liu Xiaoyan;Wang Chunyu;Liu Yang;Liu Guojun
20 Refine gene functional similarity network based on interaction networks 期刊论文 Tian Zhen;Guo Maozu;Wang Chunyu;Liu Xiaoyan;Wang Shiming
21 microRNA与疾病关联分析智能预测算法 奖励 郭茂祖;邹权;玄萍;刘扬;王春宇
22 Predicting Potential Drugs for Breast Cancer based on miRNA and Tissue Specificity 期刊论文 Yu Liang;Zhao Jin;Gao Lin
23 Data fusion-based algorithm for predicting miRNA–Disease associations 期刊论文 Chunyu Wang;Kai Sun
24 C3: connect separate connected components to form a succinct disease module 期刊论文 Bingbo Wang;Jie Hu;Lin Gao
25 一种基于多组学生物网络的癌症关键模块挖掘方法 期刊论文 郭茂祖;武雪剑;赵宁;刘晓燕;王春宇
26 Computational drug repositioning using meta-path-based semantic network analysis 期刊论文 Zhen Tian;Zhixia Teng;Shuang Cheng;Maozu Guo
27 Integration of multi-omics data to mine cancer-related gene modules. 期刊论文 Peng Li;Maozu Guo
28 CEPICS: A Comparison and Evaluation Platform for Integration Methods in Cancer Subtyping 期刊论文 Duan Ran;Gao Lin;Xu Han;Song Kuo;Hu Yuxuan;Wang Hongda;Dong Yongqiang;Zhang Chenxing;Jia Songwei
29 Circular Trajectory Reconstruction Uncovers Cell-Cycle Progression and Regulatory Dynamics from Single-Cell Hi-C Maps 期刊论文 Ye Yusen;Gao Lin;Zhang Shihua
30 An improved Bayesian network method for reconstructing gene regulatory network based on candidate auto selection 期刊论文 Xing Linlin;Guo Maozu;Liu Xiaoyan;Wang Chunyu;Wang Lei;Zhang Yin
31 SGFSC: speeding the gene functional similarity calculation based on hash tables 期刊论文 Tian Zhen;Wang Chunyu;Guo Maozu;Liu Xiaoyan;Teng Zhixia
32 Detection of driver modules with rarely mutated genes in cancers 期刊论文 Feng Li;Lin Gao;Bingbo Wang
33 MSTD: an efficient method for detecting multi-scale topological domains from symmetric and asymmetric 3D genomic maps 期刊论文 Ye Yusen;Gao Lin;Zhang Shihua
34 Integrative Analysis of Transcription Factor Combinatorial Interactions Using a Bayesian Tensor Factorization Approach 期刊论文 Ye Yusen;Gao Lin;Zhang Shihua
35 A large-scale investigation of long noncoding RNA secondary structures in human and mouse 期刊论文 Xingli Guo;Lin Gao;Yu Wang
36 Constructing an integrated gene similarity network for the identification of disease genes 期刊论文 Tian Zhen;Guo Maozu;Wang Chunyu;Xing LinLin;Wang Lei;Zhang Yin
37 Prediction of new drug indications based on clinical data and network modularity 期刊论文 Yu Liang;Ma Xiaoke;Zhang Long;Zhang Jing;Gao Lin
38 miRNA与疾病关联关系预测算法 期刊论文 郭茂祖;王诗鸣;刘晓燕;田侦
39 Optimal control nodes in disease-perturbed networks as targets for combination therapy 期刊论文 Hu Yuxuan;Chen Chia hui;Ding Yang yang;Wen Xiao;Wang Bingbo;Gao Lin;Tan Kai
40 LAceModule: Identification of Competing Endogenous RNA Modules by Integrating Dynamic Correlation 期刊论文 Xiao Wen;Lin Gao;Yuxuan Hu
41 一种基于连通显著性的疾病模块检测方法及系统 专利 王炳波;胡洁;高琳
42 A network embedding based method for partial multi-omics integration in cancer subtyping 期刊论文 Han Xu;Lin Gao;Mingfeng Huang
43 Human Pathway-Based Disease Network 期刊论文 Yu Liang;Gao Lin
44 Comparative pan-cancer DNA methylation analysis reveals cancer common and specific patterns 期刊论文 Yang Xiaofei;Gao Lin;Zhang Shihua
45 Inferring dysregulated pathways of driving cancer subtypes through multi-omics integration 会议论文 Kai Shi;Lin Gao;Bingbo Wang
46 基于网络表示学习的不完整多组学数据集成分析方法 专利 高琳;许晗
47 基于HeteSim的疾病关联长非编码RNA预测 期刊论文 马毅;郭杏莉;孙宇彤;苑倩倩;任阳;段然;高琳
48 microRNA结构与功能的智能预测方法 奖励 郭茂祖;邹权;周小平;王春宇;刘扬;汪国华
49 Feature related multi-view nonnegative matrix factorization for identifying conserved functional modules in multiple biological networks 期刊论文 Wang Peizhuo;Gao Lin;Hu Yuxuan;Li Feng
50 MiRTDL: A Deep Learning Approach for miRNA Target Prediction 期刊论文 Cheng Shuang;Guo Maozu;Wang Chunyu;Liu Xiaoyan;Liu Yang;Wu Xuejian
51 Comparative DNA methylation analysis to decipher common and cell type-specific patterns among multiple cell types. 期刊论文 Yang Xiaofei;Shao Xiaojian;Gao Lin;Zhang Shihua
52 Uncovering Driver DNA Methylation Events in Nonsmoking Early Stage Lung Adenocarcinoma 期刊论文 Zhang Xindong;Gao Lin;Liu Zhi-Ping;Jia Songwei;Chen Luonan
53 Combining Sparse Group Lasso and Linear Mixed Model Improves Power to Detect Genetic Variants Underlying Quantitative Traits. 期刊论文 Guo Yingjie;Wu Chenxi;Guo Maozu;Zou Quan;Liu Xiaoyan;Keinan Alon
54 基于节点支配能力相似性的功能模块检测方法 专利 高琳;王炳波
55 Gene-based nonparametric testing of interactions using distance correlation coefficient in case-control association studies 期刊论文 Yingjie Guo;Chenxi Wu;Maozu Guo
56 lncSLdb: a resource for long non-coding RNA subcellular localization. 期刊论文 Wen Xiao;Gao Lin;Guo Xingli;Li Xing;Huang Xiaotai;Wang Ying;Xu Haifu;He Ruijie;Jia Chenglong;Liang Feixiang
57 Gene Regulatory Networks Reconstruction Using the Flooding-Pruning Hill-Climbing Algorithm 期刊论文 Xing Linlin;Guo Maozu;Liu Xiaoyan;Wang Chunyu;Zhang Lei
58 Discovering potential cancer driver genes by an integrated network-based approach 期刊论文 Shi Kai;Gao Lin;Wang Bingbo
59 A Metric on the Space of kth-order reduced Phylogenetic Networks 期刊论文 Wang Juan;Guo Maozu
60 弱监督学习及其在复杂生物数据分析中的研究与应用 奖励 余国先;郭茂祖;王峻;张自力;张国基
61 Conserved Disease Modules Extracted From Multilayer Heterogeneous Disease and Gene Networks for Understanding Disease Mechanisms and Predicting Disease Treatments 期刊论文 Yu Liang;Yao Shunyu;Gao Lin;Zha Yunhong
62 Extracting Fitness Relationships and Oncogenic Patterns among Driver Genes in Cancer 期刊论文 Zhang Xindong;Gao Lin;Jia Songwei
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