酸浆属植物中多靶点抗雄激素非依赖性前列腺癌活性成分及其作用机制研究

31270399
2012
C0209.植物化学
陈丽霞
面上项目
教授
沈阳药科大学
78万元
雄激素非依赖性前列腺癌;酸浆属;作用机制;多靶点;构效关系
2013-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Metabolic profiling of Luteolin-7-O-glucoside in rat urine, plasma, bileand feces after oral administrationusing ultra-high performance liquid chromatography/quadrupoletime-of-flight mass spectrometry 期刊论文 Miaomiao Jiang|Guixiang Pan|Lixia Chen|Feng Qiu|
2 Withanolides from the stems and leaves of Physalis pubescens and their cytotoxic activity 期刊论文 Kang, Ning|Huang, Jian|Chen, Lixia|Qiu, Feng|
3 一种药物组合物及其在治疗一氧化氮的代谢异常相关疾病方面的用途 专利 陈丽霞
4 Stereo- and region- specificbiotransformation of physapubescin by fourfungal strains 期刊论文 Yuan Ting|Sun De-Juan|Gao Su-Yu|Chen Li-Xia|
5 Physalin A Induces Apoptotic Cell Death and Protective Autophagy in HT1080 Human Fibrosarcoma Cells 期刊论文 Shin-ichi Tashiro|Satoshi Onodera|Feng Qiu|Takashi Ikejima|
6 Chemical constituents from the calyces of Physalis alkekengi var. franchetii 期刊论文 Guiyang Xia|Qingyin Liu|Yaoyao Xie|Feng Qiu|
7 Anti-inflammatory labdane-type diterpenoids from Physalis angulata 期刊论文 Kang, Ning|Zhao, Feng|Chen, Li-Xia|Qiu, Feng|
8 对中药药效物质基础研究的一点思考 会议论文 陈丽霞|
9 辽宁省“百千万人才工程”百人层次 奖励 陈丽霞|
10 Physapubescin selectively induces apoptosis in VHL-null renal cell carcinoma cells through down-regulation of HIF-2 alpha and inhibits tumor growth 期刊论文 Qiu, Feng|Wu, Chunli|Denmon, Andria P.|Zi, Xiaolin|
11 A new phenol glycoside from Physalis angulata 期刊论文 Kang N|Zhao F|Chen LX|Qiu F|
12 Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells 期刊论文 Shin-ichi Tashiro|Satoshi Onodera|Feng Qiu|Takashi Ikejima|
13 Nitric oxide induces apoptosis and autophagy; autophagy down-regulates NO synthesis in physalin A-treated A375-S2 human melanoma cells 期刊论文 Shin-ichi Tashiro|Satoshi Onodera|Feng Qiu|Takashi Ikejima|
14 The withanolide: an overview 奖励 陈丽霞|
15 14种天然药物中抗肿瘤活性成分作用机制及其应用研究 奖励 王金辉|刘博|陈丽霞|
16 酸浆属植物中Withanolide类型化学成分及其生物活性研究 会议论文 陈丽霞|
17 Antiproliferative and Anti-inflammatory Withanolides from Physalis angulata 期刊论文 Ding, Li-Qin|Zhao, Feng|Chen, Li-Xia|Qiu, Feng|
18 New withanolides with TRAIL-sensitizing effect from Physalis pubescens L. 期刊论文 He, Hao|Huang, Jian|Qiu, Feng|Zi, Xiao-Lin|
19 Physapubescin selectively induces apoptosis in VHL-null renal cell carcinoma cells through down-regulation of HIF-2 alpha and inhibits tumor growth 期刊论文 Qiu, Feng|Wu, Chunli|Denmon, Andria P.|Zi, Xiaolin|
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