捻转血矛线虫诱导山羊Th9型免疫反应特点及其刺激性抗原鉴定
31872464
2018
C1805.兽医寄生虫学
严若峰
面上项目
教授
南京农业大学
60万元
信号通路;线虫;免疫机制;Th9免疫;山羊
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Combined Use of Indirect ELISA and Western Blotting with Recombinant Hepatocellular Carcinoma-Associated Antigen 59 Is a Potential Immunodiagnostic Tool for the Detection of Prepatent Haemonchus contortus Infection in Goat | 期刊论文 | Muhammad Ali ul Husnain Naqvi;Sana Zahra Naqvi;Muhammad Ali Memon;Kalibixiati Aimulajiang;Muhammad Haseeb;Lixin Xu;Xiaokai Song;Xiangrui Li;Ruofeng Yan |
| 2 | 一种捻转血矛线虫早期感染诊断试剂盒 | 专利 | 严若峰;李祥瑞;徐立新;宋小凯;冯伉梨 |
| 3 | Development and Potential Application of Ras Domain Containing Protein from Haemonchus contortus for Diagnosis of Goat Infection | 期刊论文 | Kalibixiati Aimulajiang;Man Cao;Shuyi Liao;Muhammad Ali-Ul-Husnain Naqvi;Xiaowei Tian;Zehua Li;Mingmin Lu;Shakeel Ahmed Lakho;Xiangrui Li;Lixin Xu;Xiaokai Song;Ruofeng Yan |
| 4 | Recombinant dynein light intermediate chain of Haemonchus contortus affects the functions of goat immune cells in vitro | 期刊论文 | Kalibixiati Aimulajiang;Zhaohai Wen;Faiz Muhammad Khand;Ambreen Leghari;Lixin Xu;Xiaokai Song;Xiangrui Li;Ruofeng Yan |
| 5 | Excretory/secretory proteins inhibit host immune responses by downregulating the TLR4/NF-kappa B/MAPKs signaling pathway: A possible mechanism of immune evasion in parasitic nematode Haemonchus contortus | 期刊论文 | Wen Zhaohai;Zhang Yue;Feng Jiajun;Aimulajiang Kalibixiati;Aleem Muhammad Tahir;Lu Mingmin;Xu Lixin;Song Xiaokai;Li Xiangrui;Yan Ruofeng |
| 6 | The GT1-TPS Structural Domain Protein From Haemonchus contortus Could Be Suppressive Antigen of Goat PBMCs | 期刊论文 | Zhaohai Wen;Muhammad Tahir Aleem;Kalibixiati Aimulajiang;Cheng Chen;Meng Liang;Xiaokai Song;Lixin Xu;Xiangrui Li;Ruofeng Yan |
| 7 | 捻转血矛线虫BLAODA蛋白单克隆抗体的制备及在诊断中的初步应用 | 期刊论文 | 卡力比夏提·艾木拉江;文兆海;陆明敏;徐立新;宋小凯;李祥瑞;严若峰 |
| 8 | Immunomodulatory dynamics of excretory and secretory products on Th9 immune response during Haemonchus contortus infection in goat | 期刊论文 | Muhammad Ali Memon;Muhammad Ali-ul-Husnain Naqvi;Huang Xin;Liang Meng;Muhammad Waqqas Hasan;Muhammad Haseeb;Shakeel Ahmed Lakho;Kalilixiati Aimulajiang;Yongqian Bu;Lixin Xu;Xiaokai Song;Xiangrui Li;Ruofeng Yan |
| 9 | 一种检测捻转血矛线虫感染的复合抗原与其应用 | 专利 | 严若峰;李祥瑞;徐立新;宋小凯;赖旭东 |
| 10 | Immunodiagnostic potential of recombinant tropomyosin during prepatent Haemonchus contortus infection in goat | 期刊论文 | Muhammad Ali-Ul-Husnain Naqvi;Tahseen Jamil;Sana Zahra Naqvi;Muhammad Ali Memon;Kalibixiati Aimulajiang;Muhammad Tahir Aleem;Muhammad Ehsan;Lixin Xu;Xiaokai Song;Xiangrui Li;Ruofeng Yan |
| 11 | Recombinant cold shock domain containing protein is a potential antigen to detect specific antibody during early and late infections of Haemonchus contortus in goat | 期刊论文 | Muhammad Ali-Ul-Husnain Naqvi;Kalibixiati Aimulajiang;Muhammad Ali Memon;Muhammad Waqqas Hasan;Sana Zahra Naqvi;Shakeel Ahmed Lakho;Wen Chu;Lixin Xu;Xiaokai Song;Xiangrui Li;Ruofeng Yan |
| 12 | 山羊IL-9基因克隆表达与单克隆抗体的制备 | 期刊论文 | 黄鑫;李庆江;徐立新;宋小凯;李祥瑞;严若峰 |
| 13 | Adhesion-Regulating Molecule from Haemonchus contortus: Potential Antigen for Diagnosis of Early Infection in Goats | 期刊论文 | Kalibixiati Aimulajiang;Muhammad Ali-ul-Husnain;Wen Chu;Mingmin Lu;Xiaowei Tian;Yongqian Bu;Muhammad Ali Memon;Xiangrui Li;Lixin Xu;Xiaokai Song;Ruofeng Yan |
| 14 | Unveiling the Immunomodulatory Characteristics of Haemonchus contortus Ephrin Domain Containing Protein in the Parasite–Host Interactions | 期刊论文 | Kalibixiati Aimulajiang;Zhaohai Wen;Xiaowei Tian;Shakeel Ahmed Lakho;Yang Zhang;Muhammad Ali-ul-Husnain Naqvi;Meng Liang;Xiaokai Song;Lixin Xu;Xiangrui Li;Ruofeng Yan |
| 15 | Characteristics of Biotin lipoyl attachment and 2-oxoacid dehydrogenase acyltransferase of the parasitic nematode Haemonchus contortus and its modulatory functions on goat PBMCs in vitro | 期刊论文 | Kalibixiati Aimulajiang;Zhaohai Wen;Muhammad Ali-ul-Husnain Naqvi;Meng Liang;Xiaowei Tian;Kangli Feng;Faiz Muhammad Khand;Muhammad Ali Memon;Lixin Xu;Xiaokai Song;Xiangrui Li;Ruofeng Yan |
| 16 | Histidine acid phosphatase domain-containing protein from Haemonchus contortus is a stimulatory antigen for the Th1 immune response of goat PBMCs | 期刊论文 | Zhaohai Wen;Zhaoying Zhang;Kalibixiati Aimulajiang;Muhammad Tahir Aleem;Jiajun Feng;Meng Liang;Mingmin Lu;Lixin Xu;Xiaokai Song;Xiangrui Li;Ruofeng Yan |
| 17 | In vitro characterization of Haemonchus contortus trehalose-6-phosphate phosphatase and its immunomodulatory effects on peripheral blood mononuclear cells (PBMCs) | 期刊论文 | ZhaoHai Wen;XinRan Xie;Muhammad Tahir Aleem;Kalibixiati Aimulajiang;Cheng Chen;Meng Liang;XiaoKai Song;LiXin Xu;XiangRui Li;RuoFeng Yan |
| 18 | Galectin Domain Containing Protein from Haemonchus contortus Modulates the Immune Functions of Goat PBMCs and Regulates CD4 T-Helper Cells In Vitro | 期刊论文 | Muhammad Ali-Ul-Husnain Naqvi;Muhammad Ali Memon;Tahseen Jamil;Sana Zahra Naqvi;Kalibixiati Aimulajiang;Javaid Ali Gadahi;Lixin Xu;Xiaokai Song;Xiangrui Li;Ruofeng Yan |
| 19 | Haemonchus contortus: siRNA mediated knockdown of matrix metalloproteinase 12A (MMP-12) results in reduction of infectivity | 期刊论文 | Muhammad Ali-Ul-Husnain Naqvi;Hao Li;Wenxiang Gao;Sana Zahra Naqvi;Tahseen Jamil;Kalibixiati Aimulajiang;Lixin Xu;Xiaokai Song;Xiangrui Li;Ruofeng Yan |
| 20 | Identification of excretory and secretory proteins from Haemonchus contortus inducing a Th9 immune response in goats | 期刊论文 | Meng Liang;Mingmin Lu;Muhammad Tahir Aleem;Yang Zhang;Mingyue Wang;Zhaohai Wen;Xiaokai Song;Lixin Xu;Xiangrui Li;Ruofeng Yan |
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