巨噬细胞调控管周脂肪及干细胞分化在血管损伤中的机制研究
91739303
2017
H0202.心肌损伤、修复、重构和再生
高平进
重大研究计划
研究员
上海交通大学
260万元
巨噬细胞;炎症反应;管周脂肪;干细胞;血管损伤
2018-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Perivascular adipose tissue-derived stromal cells contribute to vascular remodeling during aging. | 期刊论文 | Pan XX;Ruan CC;Liu XY;Kong LR;Ma Y;Wu QH;Li HQ;Sun YJ;Chen AQ;Zhao Q;Wu F;Wang XJ;Wang JG;Zhu DL;Gao PJ |
| 2 | Adventitial Fibroblast-derived VEGF Promotes Vasa Vasorum-associated Neointima Formation and Macrophage Recruitment. | 期刊论文 | Li XD;Hong MN;Chen J;Lu YY;Ye MQ;Yu M;Zhu DL;Gao PJ |
| 3 | B cell-derived anti-beta 2 glycoprotein I antibody contributes tohyperhomocysteinemia-aggravated abdominal aortic aneurysm. | 期刊论文 | Fangyu Shao;Yutong Miao;Yan Zhang;Lulu Han;Xiaolong Ma;Jiacheng Deng;Changtao Jiang;Wei Kong;QingboXu;Juan Feng;Xian Wang |
| 4 | Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1 alpha-ADAM17 pathway | 期刊论文 | Lian Guan;Li Xiaopeng;Zhang Linqi;Zhang Yangming;Sun Lulu;Zhang Xiujuan;Liu Huiying;Pang Yanli;Kong Wei;Zhang Tao;Wang Xian;Jiang Changtao |
| 5 | Gut microbiota and intestinal FXR mediate the clinical benefits of metformin | 期刊论文 | Sun Lulu;Xie Cen;Wang Guang;Wu Yue;Wu Qing;Wang Xuemei;Liu Jia;Deng Yangyang;Xia Jialin;Chen Bo;Zhang Songyang;Yun Chuyu;Lian Guan;Zhang Xiujuan;Zhang Heng;Bisson William H;Shi Jingmin;Gao Xiaoxia;Ge Pupu;Liu Cuihua;Krausz Kristopher W;Nichols Robert G;Cai Jingwei;Rimal Bipin;Patterson Andrew D;Wang Xian;Gonzalez Frank J;Jiang Changtao |
| 6 | Myeloid peroxisome proliferator-activated receptor gamma deficiency aggravates myocardial infarction in mice. | 期刊论文 | Shen ZX;Yang QZ;Li C;Du LJ;Sun XN;Liu Y;Sun JY;Gu HH;Sun YM;Wang J;Duan SZ |
| 7 | Hypoxic ER stress suppresses β-catenin expression and promotes cooperation between the transcription factors XBP1 and HIF1α for cell survival. | 期刊论文 | Xia Z;Wu S;Wei X;Liao Y;Yi P;Liu Y;Liu Jm;Liu Jf |
| 8 | Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice. | 期刊论文 | Du LJ;Sun JY;Zhang WC;Wang YL;Zhu H;Liu T;Gao MZ;Zheng C;Zhang YY;Liu Yuan;Liu Yan;Shao S;Zhang XQ;Leng Q;Auwerx J;Duan SZ |
| 9 | Transactivation domain of Krüppel-like factor 15 negatively regulates angiotensin II-induced adventitial inflammation and fibrosis. | 期刊论文 | Lu YY;Li XD;Zhou HD;Shao S;He S;Hong MN;Liu JC;Xu YL;Wu YJ;Zhu DL;Wang JG;Gao PJ |
| 10 | 降脂药在高同型半胱氨酸血症治疗方面的运用 | 专利 | 王宪;冯娟;姜长涛;张岩;邵钫钰 |
| 11 | Role of Complement-Related Inflammation and Vascular Dysfunction in Hypertension. | 期刊论文 | Ruan CC;Gao PJ |
| 12 | T cell-derived extracellular vesicles regulate B cell IgG production via pyruvate kinase muscle isozyme 2 | 期刊论文 | Juan Yang;Guohui Dang;Silin L¨;Huiying Liu;Xiaolong Ma;Lulu Han;Jiacheng Deng;Yutong Miao;Xiaopeng Li;Fangyu Shao;Changtao Jiang;Qingbo Xu;Xian Wang;Juan Feng |
| 13 | Mineralocorticoid receptor negatively regulates angiogenesis through repression of STAT3 activity in endothelial cells. | 期刊论文 | Zheng XJ;Liu Y;Zhang WC;Liu Y;Li C;Sun XN;Zhang YY;Xu J;Jiang X;Zhang L;Yang W;Duan SZ |
| 14 | Perivascular adipose tissue-derived PDGF-D contributes to aortic aneurysm formation during obesity. | 期刊论文 | Ze-Bei Zhang;Cheng-Chao Ruan;Jing-Rong Lin;Lian Xu;Xiao-Hui Chen;Ya-Nan Du;Meng-Xia Fu;Ling-Ran Kong;Ding-Liang Zhu;Ping-Jin Gao |
| 15 | Deficiency of Complement C3a and C5a Receptors Prevents Angiotensin II-Induced Hypertension via Regulatory T Cells. | 期刊论文 | Chen Xiao-Hui;Ruan Cheng-Chao;Ge Qian;Ma Yu;Xu Jian-Zhong;Zhang Ze-Bei;Lin Jingrong;Chen Dongrui;Zhu Dingliang;Gao Ping-Jin |
| 16 | Nuclear receptor corepressor 1 represses cardiac hypertrophy. | 期刊论文 | Li C;Sun XN;Chen BY;Zeng MR;Du LJ;Liu T;Gu HH;Liu Y;Li YL;Zhou LJ;Zheng XJ;Zhang YY;Zhang WC;Liu Y;Shi C;Shao S;Shi XR;Yi Y;Liu X;Wang J;Auwerx J;Wang ZV;Jia F;Li RG;Duan SZ |
| 17 | Adipocyte hypoxia-inducible factor 2α suppresses atherosclerosis by promoting adipose ceramide catabolism. | 期刊论文 | Xingzhong Zhang;Yangming Zhang;Pengcheng Wang;Song-Yang Zhang;Yongqiang Dong;Guangyi Zeng;Yu Yan;Lulu Sun;Qing Wu;Huiying Liu;Bo Liu;Wei Kong;Xian Wang;Changtao Jiang |
| 18 | T cell senescence accelerates Angiotensin II-induced target organ damage. | 期刊论文 | Xiaoxi Pan;Fang Wu;Xiaohui Chen;Dongrui Chen;Hongjin Chen;Lingran Kong;Chengchao Ruan;Pingjin Gao |
| 19 | Decrease of Perivascular AdiposeTissue Browning Is Associated WithVascular Dysfunction in SpontaneousHypertensive Rats During Aging | 期刊论文 | Ling-Ran Kong;Yan-Ping Zhou;Dong-Rui Chen;Cheng-Chao Ruan;Ping-Jin Gao |
| 20 | Shikonin attenuates hyperhomocysteinemia-induced CD4+ T cell inflammatory activation and atherosclerosis in ApoE-/- mice by metabolic suppression. | 期刊论文 | Si-lin Lü;Guo-hui Dang;Jia-cheng Deng;Hui-ying Liu;Bo Liu;Juan Yang;Xiao-long Ma;Yu-tong Miao;Chang-tao Jiang;Qing-bo Xu;Xian Wang;Juan Feng |
| 21 | A2A Receptor Activation Attenuates Hypertensive Cardiac Remodeling via Promoting Brown Adipose Tissue-Derived FGF21. | 期刊论文 | Cheng-Chao Ruan;Ling-Ran Kong;Xiao-Hui Chen;Yu Ma;Xiao-Xi Pan;Ze-Bei Zhang;Ping-Jin Gao |
| 22 | NSun2regulatesaneurysm formation by promoting autotaxin expression and T cell recruitment. | 期刊论文 | Yutong Miao;Yang Zhao;Lulu Han;Xiaolong Ma;Jiacheng Deng;Juan Yang;Silin Lü;Fangyu Shao;Wei Kong;Wengong Wang;Qingbo Xu;Xian Wang;Juan Feng |
| 23 | Regulation of Atrial Fibrosis by the Bone. | 期刊论文 | Yi Y;Du L;Qin M;Chen XQ;Sun XN;Li C;Du LJ;Liu Y;Liu Y;Sun JY;Tang Z;Xu M;Fang B;Liu X;Duan SZ |
| 24 | Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner | 期刊论文 | Yu Yan;Xun Wu;Songyang Zhang;Lulu Sun;Pengcheng Wang;Yang Zhao;GuangYiZeng;Bo Liu;GuohengXu;Huiying Liu;Lei Wang;Lei Wang;Changtao Jiang |
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