新型疾病分子标志物循环miRNA分离富集、高灵敏检测新技术研究

21335003
2013
B04.化学测量学
叶邦策
重点项目
教授
华东理工大学
300万元
循环miRNA;分子标志物;高灵敏检测;分离纯化;临床诊断
2014-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 DNA template-regulated intergrowth of fluorescentsilver nanocluster emitter pair 期刊论文 Jin-Liang Ma;Bin-Cheng Yin;叶邦策
2 Sirtuin-dependent reversible lysine acetylationof glutamine synthetases reveals an auto-feedback loop in nitrogen metabolism 期刊论文 Di You;Bin-Cheng Yin;Zhi-Hai Li;Ying Zhou;Wen-Bang Yu;Peng Zuo;叶邦策
3 Direct exosome quantification via bivalent-cholesterol-labeled DNA anchor for signal amplification 期刊论文 Fang He;Hui Liu;Xinggang Guo;Bin-Cheng Yin;叶邦策
4 GlnR-mediated regulation of short-chain fatty acids assimilation at transcriptional and posttranslational levels in Mycobacterium smegmatis 期刊论文 Xin-Xin Liu;Meng-Jia Shen;Wei-Bing Liu;Bang-Ce Ye
5 Copper-Mediated DNA-Scaffolded SilverNanocluster on-off Switch for Detection of Pyrophosphate and AlkalinePhosphatase 期刊论文 Jin-Liang Ma;Bin-Cheng Yin;Xin Wu;叶邦策
6 The rapid detection of microRNA based on p19-enhanced fluorescence polarization 期刊论文 He Yuan-Chen;Yin Bin-Cheng;Jiang Lihua;Ye Bang-Ce
7 A new mode to light up adjacent DNA-scaffolded silver probe pair and its application for specific DNA detection 期刊论文 Bin-Cheng Yin;Jin-Liang Ma;Huynh-Nhu Le;Shilong Wang;Zengguang Xu;叶邦策
8 增塑剂的检测方法 专利 叶邦策;张闽
9 Protein Acetylation and Butyrylation Regulate the Phenotype and Metabolic Shifts of the Endospore-forming Clostridium acetobutylicum. 期刊论文 Xu Jun-Yu;Xu Zhen;Liu XinXin;Tan Minjia;Ye Bang-Ce
10 一种基于磁珠偶联抗体富集并检测样本中miRNA的方法及配套微流控装置 专利 叶邦策;吴姗;左鹏
11 一种使用免疫磁珠分离血清中外泌体的方法 专利 叶邦策;倪自鹏
12 Highly sensitive surface-enhanced Raman scattering detection of hexavalent chromium based on hollow sea urchin-like TiO2@Ag nanoparticle substrate 期刊论文 Zhou Wen;Yin Bin-Cheng;Ye Bang-Ce
13 一种RNA聚合酶和连接酶偶联反应介导的定量检测核酸的PCR分析方法 专利 叶邦策;尹斌成;于翠媛
14 一种恒温扩增反应试剂 专利 叶邦策;尹斌成;史阳
15 A novel, colorimetric method for biogenic aminedetection based on arylalkylamine N-acetyltransferase 期刊论文 Pei-Qiang Leng;Feng-Lan Zhao;Bin-Cheng Yin;叶邦策
16 A versatile proximity-dependent probe based onlight-up DNA-scaffolded silver nanoclusters 期刊论文 Jin-Liang Ma;Bin-Cheng Yin;叶邦策
17 Highly sensitive surface-enhanced Raman scattering detection of adenosine triphosphate based on core-satellite assemblies 期刊论文 Ya-Fei Tian;Wen Zhou;Bin-Cheng Yin;叶邦策
18 A Novel Chemiluminescence Resonance EnergyTransfer Method for MicroRNA Detection 期刊论文 Qian Wang;Bin-Cheng Yin;叶邦策
19 Nicotinamide adenine dinucleotide detection based on silver nanoclusters stabilized by a dumbbell-shaped probe 期刊论文 Hong-Ya Wang;Jin-Liang Ma;Bin-Cheng Yin;叶邦策
20 分子识别过程的信号转换机制及高效生物传感设计 奖励 叶邦策;尹斌成;左鹏;张闽
21 调控基因dasR对红色糖多孢菌次级代谢产物合成方法及其应用 专利 叶邦策;廖成衡
22 A Cost-effective Z-Folding Controlled Liquid Handling Microfluidic Paper Analysis Device forPathogen Detection via ATP Quantification 期刊论文 Sheng-Quan Jin;Su-Miao Guo;Peng Zuo;叶邦策
23 The TetR family transcriptional regulator PccD negatively controls propionyl coenzyme A assimilation in Saccharopolyspora erythraea 期刊论文 Zhen Xu;Miao-Miao Wang;叶邦策
24 Magnetic-Based Microfluidic Device for On-Chip Isolation and Detection of Tumor-Derived Exosomes. 期刊论文 Xu Huiying;Liao Chong;Zuo Peng;Liu Ziwen;Ye Bang-Ce
25 Beyond nitrogen: GlnR regulates uptake and utilization of non-phosphotransferase-system carbon sources in actinomycetes 期刊论文 Chengheng Liao;Li-Li Yao;Ya Xu;Wei-Bing Liu;Ying Zhou;Bang-Ce Ye
26 Eis, a novel family of arylalkylamine N-acetyltransferase (EC 2.3.1.87). 期刊论文 Pan Qian;Zhao Feng-Lan;Ye Bang-Ce
27 Enzyme-free Detectionof Sequence-Specific MicroRNAs based on Nanoparticle-Assisted SignalAmplification Strategy 期刊论文 Ru-DongLi;QianWang;Bin-ChengYin;叶邦策
28 Simple and Cost-Effective Glucose Detection Based on Carbon Nanodots Supported on Silver Nanoparticles 期刊论文 Jin-Liang Ma;Bin-Cheng Yin;Xin Wu;叶邦策
29 DNA-hosted Hoechst dye: application for label-free fluorescent monitoring of endonuclease activity and inhibition 期刊论文 Xiao-Qin Jiang;Su-Miao Guo;Min Zhang;叶邦策
30 Transcriptional and post-translational regulation of AccD6 in Mycobacterium smegmatis. 期刊论文 Liu Xin-Xin;Shen Meng-Jia;Liu Wei-Bing;Ye Bang-Ce
31 Rational engineering of dynamic, entropy-driven DNA nanomachine for intracellular microRNA imaging 期刊论文 Cheng-Pin Liang;Pei-Qiang Ma;Hui Liu;Xinggang Guo;Bin-Cheng Yin;叶邦策
32 定量检测microRNA 的PCR 分析方法 专利 叶邦策;尹斌成;于翠媛
33 Time-Resolved Probes Based on Guanine/Thymine-Rich DNA-Sensitized Luminescence of Terbium (III) 期刊论文 Min Zhang;Huynh-Nhu Le;Xiao-Qin Jiang;Bin-Cheng Yin;叶邦策
34 Highly sensitive detection of exosomes by SERS using gold nanostar@ Raman reporter@ nanoshell structures modified with a bivalent cholesterollabeled DNA anchor 期刊论文 Tian Ya-Fei;Ning Cui-Fang;He Fang;Yin Bin-Cheng;Ye Bang-Ce
35 Protein Acylation Affects the Artificial Biosynthetic Pathway for Pinosylvin Production in Engineered E. coli. 期刊论文 Xu Jun-Yu;Xu Ya;Chu Xiaohe;Tan Minjia;Ye Bang-Ce
36 Protein Acylation is a General Regulatory Mechanism in Biosynthetic Pathway of Acyl-CoA-Derived Natural Products 期刊论文 Jun-Yu Xu;Ya Xu;Zhen Xu;Lin-Hui Zhai;Yang Ye;Yingming Zhao;Xiaohe Chu;Minjia Tan;Bang-Ce Ye
37 Nitrogen regulator GlnR directly control transcription of genes encoding lysine deacetylases in actinobacteria 期刊论文 Ying Xu;Di You;叶邦策
38 Ultrasensitive, Colorimetric Detection of MicroRNAs based on Isothermal Exponential Amplification Reaction-Assisted Gold Nanoparticle Amplification 期刊论文 Ru-Dong Li;Bin-Cheng Yin;叶邦策
39 A Low-cost and Simple Paper-based Microfluidic Device for Simultaneous Multiplex Determination of Different Types of Chemical Contaminants in Food 期刊论文 Yali Zhang;Peng Zuo;叶邦策
40 A Novel Molecular Beacon-based Method for Isothermal Detection of Sequence-Specific DNA via T7 RNA Polymerase-Aided Target Regeneration. 期刊论文 Bin-Cheng Yin;Shan Wu;Jin-Liang Ma;叶邦策
41 High GC Content Cas9-Mediated Genome-Editing and Biosynthetic Gene Cluster Activation in Saccharopolyspora erythraea. 期刊论文 Liu Yong;Wei Wen-Ping;Ye Bang-Ce
42 一种利用恒温扩增反应合成荧光纳米银簇探针定量检测microRNA的分析方法 专利 叶邦策;尹斌成;刘玉强
43 An Improved Ligation-Mediated PCR Method Coupled with T7 RNA Polymerase for Sensitive DNA Detection 期刊论文 Cui-Yuan Yu;Bin-Cheng Yin;Shilong Wang;Zengguang Xu;叶邦策
44 Colorimetric detection for sequence-specific microRNAbased on duplex-specific nuclease-assisted nanoparticle amplification 期刊论文 Qian Wang;Ru-Dong Li;Bin-Cheng Yin;叶邦策
45 A genetically encoded biosensor for in vitro andin vivo detection of NADP+ 期刊论文 Feng-LanZhao;ChangZhang;ChenZhang;YunTang;叶邦策
46 Acetyl-CoA synthetases of Saccharopolyspora erythraea are regulated by the nitrogen response regulator GlnR at both transcriptional and post-translational levels 期刊论文 Di You;Miao-Miao Wang;叶邦策
47 Label-free fluorescent assay of ATP based on an aptamer-assisted light-up of Hoechst dyes 期刊论文 Le Huynh-Nhu;Jiang Xiao-Qin;Zhang Min;Ye Bang-Ce
48 Quantification of Exosome Based on a Copper-Mediated Signal Amplification Strategy 期刊论文 He Fang;Wang Jing;Yin Bin-Cheng;Ye Bang-Ce
49 A single fluorescent protein-based sensor for in vivo 2-oxogluatarate detection in cell 期刊论文 Zhang Chang;Ye Bang-Ce
50 High levels of iron mitigate fusaricidin-inducedmembrane damage and reduce membrane fluidity, leading to enhanced drug resistancein Bacillus subtilis 期刊论文 Wen-Bang Yu;叶邦策
51 Simultaneous SERS detection of multiplexed microRNA biomarkers 期刊论文 Wen Zhou;Yafei Tian;Bin-Cheng Yin;叶邦策
52 A graphene oxide-based fluorescent “on/off” switch for visual bioassay using “molecular beacon”-hosted Hoechst dyes 期刊论文 Min Zhang;Huynh-Nhu Le;叶邦策
53 Sensitive detection of microRNA in complex biological samples via enzymatic signal amplification using DNA polymerase coupled with nicking endonuclease 期刊论文 Bin-Cheng Yin;Yu-Qiang Liu;叶邦策
54 Identification and characterization of two types of amino acid-regulated acetyltransferases in actinobacteria 期刊论文 Yu-Xing Lu;Xin-Xin Liu;Wei-Bin Liu;叶邦策
55 A dual signal amplification method for exosome detection based on DNA dendrimer self-assembly 期刊论文 Mei-Ling Gao;Fang He;Bin-Cheng Yin;Bang-Ce Ye
56 Site-specific and kinetic characterization of enzymatic and nonenzymatic protein acetylation 期刊论文 Miao-Miao Wang;Di You;叶邦策
57 A novel DNA-scaffolded silver nanocluster linearmolecular beacon for sequence-specific DNA detection via cyclic exonuclease IIIenzymatic amplification 期刊论文 Jin-Liang Ma;Bin-Cheng Yin;叶邦策
58 A Label-Free Method for DNA Detection based onMetal Surface Energy Transfer between Fluorescent DNA-Scaffolded SilverNanoclusters String and Gold Nanoparticle 期刊论文 Jin-Liang Ma;Bin-Cheng Yin;Huynh-Nhu Le;叶邦策
59 Lysine malonylome together with acetylome mayaffect the central metabolism and erythromycin biosynthesis pathway in Saccharopolyspora erythraea 期刊论文 Jun-Yu Xu;Zhen Xu;Ying Zhou;叶邦策
60 Transcriptional profiling analysis of Bacillus subtilis in response to excessFe3+ 期刊论文 Wen-Bang Yu;叶邦策
61 A highly integrated DNA nanomachine operating in living cells powered by an endogenous stimulus 期刊论文 Ma Pei-Qiang;Liang Cheng-Pin;Zhang He-Hua;Yin Bin-Cheng;Ye Bang-Ce
62 Imaging and tracing of intracellular metabolites utilizing genetically encoded fluorescent biosensors 期刊论文 Zhang Chang;Wei Zi-Han;Ye Bang-Ce
63 一种红霉素合成的调控基因phoP及其制备方法和应用 专利 叶邦策;姚荔丽
64 一种恒温扩增反应试剂 专利 叶邦策;尹斌成;史阳
65 Copper-Mediated DNA-Scaffolded SilverNanocluster on-off Switch for Detection of Pyrophosphate and AlkalinePhosphatase 期刊论文 Jin-Liang Ma;Bin-Cheng Yin;Xin Wu;叶邦策
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