胚胎干细胞来源exosomes调控BMSCs的命运防治骨质疏松的作用及机制

81871833
2018
H20.康复医学
汪泱
面上项目
研究员
上海交通大学
57万元
细胞衰老;骨髓间充质干细胞;骨质疏松;胚胎干细胞;外泌体
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells 期刊论文 Gong Liangzhi;Chen Bi;Zhang Juntao;Sun Yongjin;Yuan Ji;Niu Xin;Hu Guowen;Chen Yu;Xie Zongping;Deng Zhifeng;Li Qing;Wang Yang
2 Small extracellular vesicles derived from embryonic stem cells restore ovarian function of premature ovarian failure through PI3K/AKT signaling pathway 期刊论文 Liu Mengyu;Qiu Yu;Xue Zhuowei;Wu Ruoyu;Li Jie;Niu Xin;Yuan Ji;Wang Yang;Wu Qingkai
3 Exosomes from human urine‐derived stem cells enhanced neurogenesis via miR‐26a/HDAC6 axis after ischaemic stroke 期刊论文 Xiaozheng Ling;Guowei Zhang;Yuguo Xia;Qingwei Zhu;Juntao Zhang;Qing Li;Xin Niu;Guowen Hu;Yunlong Yang;Yang Wang;Zhifeng Deng
4 Embryonic Stem Cells-Derived Exosomes Endowed with Targeting Properties as Chemotherapeutics Delivery Vehicles for Glioblastoma Therapy 期刊论文 Qingwei Zhu;Xiaozheng Ling;Yunlong Yang;Juntao Zhang;Qing Li;Xin Niu;Guowen Hu;Bi Chen;Haiyan Li;Yang Wang;Zhifeng Deng
5 Embryonic Stem Cell Derived Small Extracellular Vesicles Modulate Regulatory T Cells to Protect against Ischemic Stroke 期刊论文 Xia Yuguo;Hu Guowen;Chen Yu;Yuan Ji;Zhang Juntao;Wang Sifan;Li Qing;Wang Yang;Deng Zhifeng
6 ESC-sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia 期刊论文 Guowen Hu;Yuguo Xia;Juntao Zhang;Yu Chen;Ji Yuan;Xin Niu;Bizeng Zhao;Qing Li;Yang Wang;Zhifeng Deng
7 Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke 期刊论文 Yuguo Xia;Xiaozheng Ling;Guowen Hu;Qingwei Zhu;Juntao Zhang;Qing Li;Bizeng Zhao;Yang Wang;Zhifeng Deng
8 ESC-sEVs rejuvenate aging hippocampal NSCs by transferring SMADs to regulate the MYT1-Egln3-Sirt1 axis 期刊论文 Hu Guowen;Xia Yuguo;Chen Bi;Zhang Juntao;Gong Liangzhi;Chen Yu;Li Qing;Wang Yang;Deng Zhifeng
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