小分子化合物靶向SF-1促间充质干细胞诱导分化为Leydig样细胞的实验研究

81871149
2018
H0404.男性生殖内分泌异常及相关疾病
孙杰
面上项目
主任医师
上海交通大学
57万元
性腺功能低下症;间充质干细胞;睾丸间质细胞;小分子化合物
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 CRISPR/dCas9-mediated activation of multiple endogenous target genes directly converts human foreskin fibroblasts into Leydig-like cells 期刊论文 Huang Hua;Zou Xiangyu;Zhong Liang;Hou Yanping;Zhou Jin;Zhang Zhiyuan;Xing Xiaoyu;Sun Jie
2 Renal denervation alleviates renal ischemic reperfusion injury-induced acute and chronic kidney injury in rats partly by modulating miRNAs 期刊论文 Xiangyu Zou;Sihao Lin;Liang Zhong;Jie Liu;Yu Meng;Yingjian Zhu;Jie Sun
3 Mitochondria transfer via tunneling nanotubes is an important mechanism by which CD133+ scattered tubular cells eliminate hypoxic tubular cell injury 期刊论文 Xiangyu Zou;Yanping Hou;Jinxia Xu;Liang Zhong;Jin Zhou;Guangyuan Zhang;Jie Sun
4 骶神经调控对学龄前期神经源性膀胱患者尿动力学参数的影响 期刊论文 张志远;钟量;邹翔宇;赵海腾;孙杰
5 Conversion of human fibroblasts into functional Leydig-like cells by small molecules and a single factor 期刊论文 Jin Zhou;Yanping Hou;Zhiyuan Zhang;Xiaoyu Xing;Xiangyu Zou;Liang Zhong;Hua Huang;Zhen Zhang;Jie Sun
6 儿童异基因造血干细胞移植后出血性膀胱炎早期症状与外科治疗的分析 期刊论文 刘鹏涛;张志远;柏凯平;邢晓宇;邹翔宇;孙杰
7 A Revolution in Reprogramming: Small Molecules 期刊论文 Jin Zhou;Jie Sun
8 一种诱导人成纤维细胞重编程为Leydig样细胞的方法 专利 孙杰;周瑾
9 Human umbilical cord multipotent mesenchymal stromal cells alleviate acute ischemia-reperfusion injury of spermatogenic cells via reducing inflammatory response and oxidative stress 期刊论文 Zhong Liang;Yang Mengbo;Zou Xiangyu;Du Tao;Xu Huiming;Sun Jie
10 Ability of volume measures of hydronephrosis to predict need for surgery and evaluate renal function in children with ureteropelvic junction obstruction 期刊论文 Kaiping Bai;Yanping Hou;Zhiyuan Zhang;Xiaoyu Xing;Weiwen Zhu;Xiangyu Zou;Jie Sun
11 Retroperitoneoscopic renal and adrenal specimen resection surgery in children 期刊论文 Zhong Liang;Zou Xiangyu;Sun Jie
12 Leydig-like cells derived from reprogrammed human foreskin fibroblasts by CRISPR/dCas9 increase the level of serum testosterone in castrated male rats 期刊论文 Huang Hua;Zhong Liang;Zhou Jin;Hou Yanping;Zhang Zhiyuan;Xing Xiaoyu;Sun Jie
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