B淋巴细胞特异性BCR-ABL致癌通路的鉴定与机制研究
81870112
2018
H0809.白血病
任瑞宝
面上项目
研究员
上海交通大学
55万元
信号通路;骨髓移植;白血病发病;细胞内定位;费城染色体
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | GNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner | 期刊论文 | Xia Z;Zhang X;Liu P;Zhang R;Huang Z;Li D;Xiao X;Wu M;Ning N;Zhang Q;Zhang J;Liu M;Jiao B;Ren R. |
| 2 | Focal Adhesion Kinase (FAK) Inhibition Synergizes with KRAS G12C Inhibitors in Treating Cancer through the Regulation of the FAK-YAP Signaling. | 期刊论文 | Zhang Baoyuan;Zhang Yan;Zhang Jiangwei;Liu Ping;Jiao Bo;Wang Zaiqi;Ren Ruibao |
| 3 | Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition | 期刊论文 | Xiao X;Liu P;Li D;Xia Z;Wang P;Zhang X;Liu M;Liao L;Jiao B;Ren R. |
| 4 | Palmitoylation of GNAQ/11 is critical for tumor cell proliferation and survival in GNAQ/11-mutant uveal melanoma | 期刊论文 | Yan Zhang;Baoyuan Zhang;Yongyun Li;Yuting Dai;Jiaoyang Li;Donghe Li;Zhizhou Xia;Jianming Zhang;Ping Liu;Ming Chen;Bo Jiao;Ruibao Ren |
| 5 | DDB1- and CUL4-associated factor 8 plays a critical role in spermatogenesis | 期刊论文 | Xiuli Zhang;Zhizhou Xia;Xingyu Lv;Donghe Li;Mingzhu Liu;Ruihong Zhang;Tong Ji;Ping Liu;Ruibao Ren |
| 6 | IRF8 Impacts Self-Renewal of Hematopoietic Stem Cells by Regulating TLR9 Signaling Pathway of Innate Immune Cells. | 期刊论文 | Li Donghe;Zhang Yuyin;Qiu Qingsong;Wang Jinzeng;Zhao Xuemei;Jiao Bo;Zhang Xiuli;Yu Shanhe;Xu Pengfei;Dan Yuqing;Xiao Xinhua;Wang Peihong;Liu Mingzhu;Xia Zhizhou;Huang Zhangsen;Zhang Ruihong;Li Jiaoyang;Xie Xi;Zhang Yan;Liu Chenxuan;Liu Ping;Ren Ruibao |
| 7 | PTPN2 regulates the activation of KRAS and plays a critical role in proliferation and survival of KRAS-driven cancer cells | 期刊论文 | Huang Z;Liu M;Li D;Tan Y;Zhang R;Xia Z;Wang P;Jiao B;Liu P;Ren R. |
| 8 | A dual inhibitor overcomes drug-resistant FLT3-ITD acute myeloid leukemia. | 期刊论文 | Wang Peihong;Xiao Xinhua;Zhang Yuyin;Zhang Baoyuan;Li Donghe;Liu Mingzhu;Xie Xi;Liu Chenxuan;Liu Ping;Ren Ruibao |
| 9 | IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia | 期刊论文 | Xiao Huang;Tingting Ma;Yong-Mei Zhu;Bo Jiao;Shan-He Yu;Kankan Wang;Jian-Qing Mi;Ruibao Ren |
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