靶向诱导merlin/p53协同性亚细胞穿梭对听神经瘤在体生长的影响

81800898
2018
H1403.耳及侧颅底疾病
陈洪赛
青年科学基金项目
医师
上海交通大学
21万元
生长抑制因子;动物模型;治疗;前庭神经鞘膜细胞;发病机制
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Synergistic effect of Nutlin-3 combined with MG-132 on schwannoma cells through restoration of merlin and p53 tumour suppressors 期刊论文 Chen Hongsai;Xue Lu;Huang He;Wang Hantao;Zhang Xiaoman;Zhu Weidong;Wang Zhigang;Wang Zhaoyan;Wu Hao
2 Age-dependent copy number variations of TP53 tumour suppressor gene associated with altered phosphorylation status of p53 protein in sporadic schwannomas 期刊论文 Hongsai Chen;He Huang;Jingjing Zhao;Zhigang Wang;Mengling Chang;Lu Xue;Weidong Zhu;Yongchuan Chai;Gen Li;Zhaoyan Wang;Hao Wu
3 High throughput proteomic and metabolic profiling identified target correction of metabolic abnormalities as a novel therapeutic approach in head and neck paraganglioma. 期刊论文 Zhigang Wang;Hongsai Chen;Lu Xue;Weiwei He;Wenying Shu;Hao Wu;Zhaoyan Wang
4 Proteomic screening identifies PML/p53 axis as a potential treatment target of facial nerve schwannomas 期刊论文 Zhigang Wang;Hongsai Chen;Lu Xue;Weiwei He;Lianying Jiang;Zhaoyan Wang;Hao Wu
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