帕金森病异动症发生中mBDNF-TrKB/proBDNF-p75NTR通路参与皮质-纹状体突触功能调控

81771211
2017
H0904.运动障碍性疾病
刘振国
面上项目
主任医师
上海交通大学
54万元
左旋多巴诱发的异动症;成熟型脑源性神经营养因子;帕金森病
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Partial Depletion of Peripheral M1 Macrophages Reverses Motor Deficits in MPTP-Treated Mouse by Suppressing Neuroinflammation and Dopaminergic Neurodegeneration 期刊论文 Aijuan Yan;Yu Zhang;Jingya Lin;Lu Song;Xijin Wang;Zhenguo Liu
2 The abnormal activation of D1R/Shp-2 complex involved in levodopa-induced dyskinesia in 6-hydroxydopamine-lesioned Parkinson’s rats 期刊论文 Na Wu;Ying Wan;Lu Song;Chen Qi;Zhenguo Liu;Jing Gan
3 L-3,4-Dihydroxyphenylalanine Recovers Circadian Rhythm Disturbances in the Rat Models of Parkinson's Disease by Regulating the D1R-ERK1/2-mTOR Pathway 期刊论文 Shuyuan Yang;Ying Wan;Na Wu;Lu Song;Zhihua Liu;Jiahao Zhao;Ying Liu;Zhenguo Liu;Jing Gan
4 The p75 neurotrophin receptor as a novel intermediate in L-dopa-induced dyskinesia in experimental Parkinson’s disease 期刊论文 Zhihua Liu;Aijuan Yan;Jiahao Zhao;Shuyuan Yang;Lu Song;Zhenguo Liu
5 Systemic Inflammation Increases the Susceptibility to Levodopa-Induced Dyskinesia in 6-OHDA Lesioned Rats by Targeting the NR2B-Medicated PKC/MEK/ERK Pathway 期刊论文 Aijuan Yan;Lu Song;Yu Zhang;Xijin Wang;Zhenguo Liu
6 Exploring the association between Cerebral small‐vessel diseases and motor symptoms in Parkinson's disease 期刊论文 Ying Wan;Wenjian Hu;Jing Gan;Lu Song;Na Wu;Yuzhen Chen;Zhenguo Liu
7 Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson’s Disease Mice 期刊论文 Aijuan Yan;Zhihua Liu;Lu Song;Xijin Wang;Yu Zhang;Na Wu;Jingya Lin;Ying Liu;Zhenguo Liu
8 帕金森病患者黄斑区视网膜厚度变化的特点分析 期刊论文 赵嘉豪;吴娜;万赢;宋璐;干静;刘振国
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