CircKrt4通过外泌体介导的细胞间转运对肺血管重构的调控研究
81873412
2018
H0107.肺循环与肺血管疾病
马翠
面上项目
教授
哈尔滨医科大学
57万元
增殖;肺动脉高压;外泌体;环状RNA;肺动脉平滑肌细胞
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | circRNA CDR1as Promotes Pulmonary Artery Smooth Muscle Cell Calcification by Upregulating CAMK2D and CNN3 via Sponging miR-7-5p | 期刊论文 | Cui Ma;Rui Gu;Xiaoying Wang;Siyu He;June Bai;Lixin Zhang;Junting Zhang;Qian Li;Lihui Qu;Wei Xin;Yuan Jiang;Fei Li;Xijuan Zhao;Daling Zhu |
| 2 | Programmed death-ligand 1 triggers PASMCs pyroptosis and pulmonary vascular fibrosis in pulmonary hypertension | 期刊论文 | Zhang Min;Xin Wei;Yu Yang;Yang Xinying;Ma Cui;Zhang Hongyue;Liu Ying;Zhao Xijuan;Guan Xue;Wang Xiaoying;Zhu Daling |
| 3 | 肺动脉高压发病的分子机制及治疗药物的研究 | 奖励 | 刘云;孙增先;马翠;孙舒扬;朱金权;曹永刚 |
| 4 | 线粒体稳态失衡对肺动脉高压致病作用的系统性研究 | 奖励 | 马翠;张立新;刘云;于秀峰;赵喜娟 |
| 5 | LncRNA FENDRR with m6A RNA methylation regulates hypoxia-induced pulmonary artery endothelial cell pyroptosis by mediating DRP1 DNA methylation | 期刊论文 | Xiaoying Wang;Qian Li;Siyu He;June Bai;Cui Ma;Lixin Zhang;Xiaoyu Guan;Hao Yuan;Yiying Li;Xiangrui Zhu;Jian Mei;Feng Gao;Daling Zhu |
| 6 | RPS4XL encoded by lnc-Rps4l inhibits hypoxia-induced pyroptosis by binding HSC70 glycosylation site | 期刊论文 | Yiying Li;Junting Zhang;Hanliang Sun;Xiufeng Yu;Yujie Chen;Cui Ma;Xiaodong Zheng;Lixin Zhang;Xijuan Zhao;Yuan Jiang;Wei Xin;Shanshan Wang;Jiye Hu;Mingge Wang;Daling Zhu |
| 7 | Exosomal 15-LO2 mediates hypoxia-induced pulmonary artery hypertension in vivo and in vitro. | 期刊论文 | Zhang Min;Xin Wei;Ma Cui;Zhang Hongyue;Mao Min;Liu Ying;Zheng Xiaodong;Zhang Lixin;Yu Xiufeng;Li Huajian;Zhu Daling |
| 8 | Circ-calm4 Serves as an miR-337-3p Sponge to Regulate Myo10 (Myosin 10) and Promote Pulmonary Artery Smooth Muscle Proliferation | 期刊论文 | Zhang Junting;Li Yiying;Qi Jing;Yu Xiufeng;Ren Huanhuan;Zhao Xijuan;Xin Wei;He Siyu;Zheng Xiaodong;Ma Cui;Zhang Lixin;Wu Bingxiang;Zhu Daling |
| 9 | MiR-449a-5p mediates mitochondrial dysfunction and phenotypic transition by targeting Myc in pulmonary arterial smooth muscle cells | 期刊论文 | Zhang Chen;Ma Cui;Zhang Lixin;Zhang Linlin;Zhang Fengying;Ma Mingfei;Zheng Xiaodong;Mao Min;Shen Tingting;Zhu Daling |
| 10 | MicroRNA-874-5p regulates autophagy and proliferation in pulmonary artery smooth muscle cells by targeting Sirtuin 3 | 期刊论文 | Zhang L;Ma C;Wang X;Bai J;He S;Zhang J;Xin W;Li Y;Jiang Y;Li J;Zhu D |
| 11 | 花生四烯酸代谢产物、非编码RNA在肺动脉高压发病中的作用及基于潜在治疗靶点的药物研究 | 奖励 | 朱大岭;马翠;王志刚;王爽;郑晓东;于秀峰;曲丽辉;邢妍 |
| 12 | 脂多糖通过介导MFN1泛素化调控小鼠Raw264.7巨噬细胞线粒体稳态失衡和焦亡 | 期刊论文 | 梅健;朱祥瑞;欧琅琳;王朝思;张立新;吕跃山;王晓颖;和思燏;白君娥;袁昊;管晓宇;马翠 |
| 13 | Ubiquitinated AIF is a major mediator of hypoxia-induced mitochondrial dysfunction and pulmonary artery smooth muscle cell proliferation | 期刊论文 | Cui Ma;Xiaoying Wang;Siyu He;Lixin Zhang;June Bai;Lihui Qu;Jing Qi;Xiaodong Zheng;Xiangrui Zhu;Jian Mei;Xiaoyu Guan;Hao Yuan;Daling Zhu |
| 14 | Lipopolysaccharide-induced proliferation and glycolysis in airway smooth muscle cells via activation of Drp1. | 期刊论文 | Zhang Lixin;Ma Cui;Wang Xiaoying;He Siyu;Li Qian;Zhou Yutian;Liu Ying;Zhang Min;Yu Xiufeng;Zhao Xijuan;Li Fei;Zhu Da Ling |
| 15 | piRNA‐63076 contributes to pulmonary arterial smooth muscle cell proliferation through acyl‐CoA dehydrogenase | 期刊论文 | Ma Cui;Zhang Lixin;Wang Xiaoying;He Siyu;Bai June;Li Qian;Zhang Min;Zhang Chen;Yu Xiufeng;Zhang Junting;Xin Wei;Li Yiying;Zhu Daling |
| 16 | GLI1 mediated pulmonary artery smooth muscle cell pyroptosis contributes to hypoxia induced pulmonary hypertension | 期刊论文 | Siyu He;Cui Ma;Lixin Zhang;June Bai;Xiaoying Wang;Xiaodong Zheng;Junting Zhang;Wei Xin;Yiying Li;Yuan Jiang;Sen Wang;Daling Zhu |
| 17 | Mito-Tempo在LPS诱导的肺动脉内皮细胞损伤中的作用 | 期刊论文 | 张立新;王晓颖;和思燏;白君娥;朱祥瑞;梅健;马翠 |
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