心力衰竭时线粒体稳态失衡的新机制：BDNF-TrkB-STAT3-AMPK

81870191
2018
H0202.心肌损伤、修复、重构和再生
杭鹏洲
面上项目
研究员
哈尔滨医科大学
57万元
线粒体;心力衰竭;信号传导及转录激活因子3;腺苷酸活化蛋白激酶;BDNF/TrkB通路
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Small-molecule 7,8-dihydroxyflavone counteracts compensated and decompensated cardiac hypertrophy via AMPK activation 期刊论文 Peng-Zhou Hang;Pei-Feng Li;Jie Liu;Feng-Feng Li;Ting-Ting Chen;Yang Pan;Man-Ru Zhang;Hua-Qing Yu;Hong-Yu Ji;Zhi-Min Du;Jing Zhao
2 Activation of cardiac TrkB receptor by its small molecular agonist 7,8-dihydroxyflavone inhibits doxorubicin-induced cardiotoxicity via enhancing mitochondrial oxidative phosphorylation 期刊论文 Jing Zhao;Jingjing Du;Yang Pan;Tingting Chen;Lihui Zhao;Yanmeng Zhu;Yingfu Chen;Yuyang Zheng;Yu Liu;Lihui Sun;Pengzhou Hang;Zhimin Du
3 The emerging role of BDNF/TrkB signaling in cardiovascular diseases 期刊论文 Peng-Zhou Hang;Hua Zhu;Pei-Feng Li;Jie Liu;Feng-Qin Ge;Jing Zhao;Zhi-Min Du
4 Inhibition of miR-23a attenuates doxorubicin-induced mitochondria-dependent cardiomyocyte apoptosis by targeting the PGC-1α/Drp1 pathway 期刊论文 Jingjing Du;Pengzhou Hang;Yang Pan;Burong Feng;Yuyang Zheng;Tingting Chen;Lihui Zhao;Zhimin DU
5 The regulatory role of BDNF/TrkB pathway in organ and tissue fibrosis 期刊论文 Peng-Zhou Hang;Feng-Qin Ge;Pei-Feng Li;Jie Liu;Hua Zhu;Jing Zhao
6 Brain-derived neurotrophic factor mimetic, 7,8-dihydroxylavone, protects against myocardial ischemia by rebalancing optic atrophy 1 processing 期刊论文 Zhen Wang;Shi-Peng Wang;Qun Shao;Pei-Feng Li;Yue Sun;Lan-Zi Luo;Xiu-Qing Yan;Zi-Yi Fan;Juan Hu;Jing Zhao;Peng-Zhou Hang;Zhi-Min Du
7 7,8-Dihydroxyflavone alleviates cardiac fibrosis by restoring circadian signals via downregulating Bmal1/Akt pathway 期刊论文 Peng-Zhou Hang;Jie Liu;Jia-Pan Wang;Feng-Feng Li;Pei-Feng Li;Qing-Nan Kong;Jing Shi;Hong-Yu Ji;Zhi-Min Du;Jing Zhao
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