As3MT基因多态性对As2O3在治疗急性早幼粒细胞白血病中的代谢及疗效影响研究

81700151
2017
H0809.白血病
海鑫
青年科学基金项目
教授
哈尔滨医科大学
20万元
三价砷甲基转移酶;三氧化二砷;急性早幼粒细胞白血病;基因多态性
2018-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Characteristics of arsenic species in cerebrospinal fluid (CSF) of acute promyelocytic leukemia (APL) patients treated with arsenic trioxide plus mannitol 期刊论文 Meihua Guo;Qilei Zhao;Shengjin Fan;Zhiqiang Wu;Liwang Lin;Hongzhu Chen;Yanhui Gao;Xin Hai
2 一种采用HPLC-HG-AFS法测定全血或红细胞中四种砷形态浓度的方法 专利 海鑫;郭美华;周晋;高春璐
3 Effect of continuous venovenous haemodialysis on outcome and pharmacokinetics of arsenic species in a patient with acute promyelocytic leukaemia and acute kidney injury 期刊论文 Gao Chunlu;Fan Shengjin;Hostetter Thomas H;Wang Wenjing;Li Jing;Guo Meihua;Zhou Jin;Hai Xin
4 Polymorphisms in arsenic (+ 3 oxidation state) methyltransferase (AS3MT) predict the occurrence of hyperleukocytosis and arsenic metabolism in APL patients treated with As2O3 期刊论文 Wensheng Liu;Xinyu Wang;Jing Lu;Yingmei Zhang;Xiangmei Ye;Jinmei Li;Qilei Zhao;Zhiqiang Wu;Jin Zhou;Xin Hai
5 As3MT 基因多态性对As2O3治疗的APL患者砷甲基化代谢及不良反应的影响研究 会议论文 鲁静;海鑫
6 Characteristics and clinical influence factors of arsenic species in plasma and their role of arsenic species as predictors for clinical efficacy in acute promyelocytic leukemia (APL) patients treated with arsenic trioxide 期刊论文 Meihua Guo;Jin Zhou;Shengjin Fan;Limin Li;Hongzhu Chen;Liwang Lin;Qilei Zhao;Xinyu Wang;Wensheng Liu;Zhiqiang Wu;Xin Hai
7 Clinical pharmacokinetics and safety profile of single agent arsenic trioxide by continuous slow-rate infusion in patients with newly diagnosed acute promyelocytic leukemia 期刊论文 Gao Chunlu;Hu Shuang;Guo Meihua;Hai Xin;Zhou Jin
8 Time course of arsenic species in red blood cells of acute promyelocytic leukemia (APL) patients treated with single agent arsenic trioxide 期刊论文 Guo Meihua;Wang Bin;Liu Shuchuan;Wang Wenjing;Gao Chunlu;Hu Shuang;Fan Shengjin;Hai Xin;Zhou Jin
9 Influence of AS3MT polymorphisms on arsenic metabolism and liver injury in APL patients treated with arsenic trioxide 期刊论文 Lu Jing;Yu Kaijiang;Fan Shengjin;Liu Wensheng;Dong Zengxiang;Li Jing;Wang Xinyu;Hai Xin;Zhou Jin
10 AS3MT Polymorphisms, Arsenic Metabolism, and the Hematological and Biochemical Values in APL Patients Treated with Arsenic Trioxide. 期刊论文 Lu Jing;Hu Shuang;Wang Wenjing;Li Jing;Dong Zengxiang;Zhou Jin;Hai Xin
11 Speciation analysis of arsenic in urine samples from APL patients treated with single agent As2O3 by HPLC-HG-AFS 期刊论文 Guo Meihua;Li Jing;Fan Shengjin;Liu Wensheng;Wang Bin;Gao Chunlu;Zhou Jin;Hai Xin
12 一种AS3MT基因单核苷酸多态性位点检测试剂盒,使用方法及应用 专利 海鑫;于凯江;刘文圣;郭美华
13 一种HPLC-ICP-MS法测定粒细胞中四种砷化物浓度的方法及应用 专利 海鑫;于凯江;王新羽;郭美华
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