调控缺血性心律失常/猝死的新靶点及中药防治作用新机制

81130088
2011
H3209.中药心脑血管药理
杨宝峰
重点项目
教授
哈尔滨医科大学
280万元
miRNAs;中药;心律失常;离子通道
2012-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Arsenic trioxide-induced hERG K+ channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression 期刊论文 Gong, Yan|Sun, Mingming|Yang, Baofeng|Li, Baoxin|
2 Bisphenol A, an environmental estrogen-like toxic chemical, induces cardiac fibrosis by activating the ERK1/2 pathway 期刊论文 Hu Y|Zhang Y|
3 A novel reciprocal loop between microRNA-21 and TGF beta RIII is involved in cardiac fibrosis 期刊论文 Zhao, Dan|Lu, Yanjie|Chu, Wenfeng|Yang, Baofeng|
4 Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling. 期刊论文 Gitau SC, Li X, Zhao D, Guo Z, Liang H, Qian M, L|
5 microRNA-124 Regulates Cardiomyocyte Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells Via Targeting STAT3 Signaling 期刊论文 Zhou, Xin|Yang, Baofeng|Wang, Xinyue|Lu, Yanjie|
6 Tanshinone IIA Improves miR-133 Expression Through MAPK ERK1/2 Pathway in Hypoxic Cardiac Myocytes 期刊论文 Xing, Shu|Wang, Haoyan|Zhang, Zhihua|Shan, Hongli|
7 Downregulation of miR-151-5p Contributes to Increased Susceptibility to Arrhythmogenesis during Myocardial Infarction with Estrogen Deprivation 期刊论文 Yu, Shaonan|Bi, Zhengang|Lu, Yanjie|Shan, Hongli|
8 Reciprocal Changes of Circulating Long Non-Coding RNAs ZFAS1 and CDR1AS Predict Acute MyocardialInfarction. 期刊论文 Wang S|Du Z|Lu Y|Yang B|
9 三氧化二砷毒性反应发生机制及防治策略 奖励 蔡本志|张勇|潘振伟|白云龙|
10 Overexpression of microRNA-1 Causes Atrioventricular Block in Rodents 期刊论文 Du, Zhimin|Yang, Baofeng|Gao, Xu|Shan, Hongli|
11 let-7e replacement yields potent anti-arrhythmic efficacy via targeting beta 1-adrenergic receptor in rat heart 期刊论文 Xu, Chaoqian|Chu, Wenfeng|Lu, Yanjie|Yang, Baofeng|
12 Arsenic-induced interstitial myocardial fibrosis reveals a new insight into drug-induced long QT syndrome 期刊论文 Dong, Deli|Lu, Yanjie|Du, Zhimin|Yang, Baofeng|
13 心血管重大疾病新药靶点的研发 奖励 单宏丽|
14 MicroRNA-328 as a regulator of cardiac hypertrophy 期刊论文 Lu, Yanjie|Ju, Jiaming|Yang, Baofeng|Shan, Hongli|
15 Bone marrow mesenchymal stem cell transplantation retards the natural senescence of rat hearts. 期刊论文 Zhang M, Liu D, Li S, Chang L, Zhang Y, Liu R, Su|
16 miR-124/ATF-6, a novel lifespan extension pathway of Astragalus polysaccharide in Caenorhabditis elegans. 期刊论文 Wang N, Liu J, Xie F, Gao X, Ye JH, Sun LY, Wei R|
17 Advances in exploring the role of microRNAs in the pathogenesis, diagnosis and therapy of cardiac diseases in China. 期刊论文 Zhenwei Pan|Yanjie Lu|Baofeng Yang|
18 Arsenic trioxide induces cardiac fibroblast apoptosis in vitro and in vivo by up-regulating TGF-beta 1 expression 期刊论文 Yan, Jinglong|Yang, Baofeng|Lu, Yanjie|Chu, Wenfeng|
19 Hydrogen peroxide induces overexpression of angiotensin-converting enzyme in human umbilical vein endothelial cells 期刊论文 Li, Xin|Chu, Wenfeng|Qiao, Guofen|Lu, Yanjie|
20 MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor-beta 1 Pathway 期刊论文 Zhang, Yang|Wang, Ying|Lu, Yanjie|Yang, Baofeng|
21 MicroRNA-1 aggravates cardiac oxidative stress by post-transcriptional modification of the antioxidant network. 期刊论文 Wang L, Yuan Y, Li J, Ren H, Cai Q, Chen X, Liang|
22 miR-1 Exacerbates Cardiac Ischemia-Reperfusion Injury in Mouse Models 期刊论文 Wang, Jinghao|Xie, Liangjun|Lu, Yanjie|Yang, Baofeng|
23 MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation 期刊论文 Wang, Zhiguo|Lu, Yanjie|Yang, Baofeng|Nattel, Stanley|
24 心源性猝死防治新靶点及其药物干预 奖励 张莹|白云龙|蔡本志|张荣|
25 Overexpression of microRNA-1 impairs cardiac contractile function by damaging sarcomere assembly 期刊论文 Sun, Li-Hua|Pan, Zhen-Wei|Li, Wei-Min|Yang, Bao-Feng|
26 Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1 alpha-mediated TRPC signalling 期刊论文 Cai, Ruijun|Dong, Deli|Lu, Yanjie|Yang, Baofeng|
27 MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor-beta 1 Pathway 期刊论文 Zhang, Yang|Wang, Ying|Lu, Yanjie|Yang, Baofeng|
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