异常DNA甲基化驱动的非编码RNA(lncRNA/ miRNA)协同调控癌症风险通路识别及其功能研究
61603116
2016
F0304.系统工程理论与技术
张云鹏
青年科学基金项目
研究员
哈尔滨医科大学
22万元
非编码RNA;功能分析;协同调控;癌症风险通路;DNA甲基化
2017-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Identifying subpathway signatures for individualized anticancer drug response by integrating multi-omics data | 期刊论文 | Xu Yanjun;Dong Qun;Li Feng;Xu Yingqi;Hu Congxue;Wang Jingwen;Shang Desi;Zheng Xuan;Yang Haixiu;Zhang Chunlong;Shao Mengting;Meng Mohan;Xiong Zhiying;Li Xia;Zhang Yunpeng |
| 2 | A comprehensive overview of oncogenic pathways in human cancer | 期刊论文 | Feng Li;Tan Wu;Yanjun Xu;Qun Dong;Jing Xiao;Yingqi Xu;Qian Li;Chunlong Zhang;Jianxia Gao;Liqiu Liu;Xiaoxu Hu;Jian Huang;Xia Li;Yunpegn Zhang |
| 3 | The LncRNA Connectivity Map: Using LncRNA Signatures to Connect Small Molecules, LncRNAs, and Diseases | 期刊论文 | Yang Haixiu;Shang Desi;Xu Yanjun;Zhang Chunlong;Feng Li;Sun Zeguo;Shi Xinrui;Zhang Yunpeng;Han Junwei;Su Fei;Li Chunquan;Li Xia |
| 4 | LncSubpathway: a novel approach for identifying dysfunctional subpathways associated with risk lncRNAs by integrating lncRNA and mRNA expression profiles and pathway topologies | 期刊论文 | Xu Yanjun;Li Feng;Wu Tan;Xu Yingqi;Yang Haixiu;Dong Qun;Zheng Meiyu;Shang Desi;Zhang Chunlong;Zhang Yunpeng;Li Xia |
| 5 | LncTarD: a manually-curated database of experimentally-supported functional lncRNA-target regulations in human diseases | 期刊论文 | Hongying Zhao;Jian Shi;Yunpeng Zhang;Aimin Xie;Lei Yu;Caiyu Zhang;Junjie Lei;Haotian Xu;Zhijun Leng;Tengyue Li;Waidong Huang;Shihua Lin;Li Wang;Yun Xiao;Xia Li |
| 6 | LncACTdb 2.0: an updated database of experimentally supported ceRNA interactions curated from low- and high-throughput experiments | 期刊论文 | Peng Wang;Xin Li;Yue Gao;Qiuyan Guo;Yanxia Wang;Ying Fang;Xueyan Ma;Hui Zhi;Dianshaung Zhou;Weitao Shen;Weisha Liu;Lihua Wang;Yunpeng Zhang;Shangwei Ning;Xia Li |
| 7 | Identifying functions and prognostic biomarkers of network motifs marked by diverse chromatin states in human cell lines | 期刊论文 | Li Wang;Hongying Zhao;Jing Li;Yingqi Xu;Yujia Lan;Wenkang Yin;Xiaoqin Liu;Lei Yu;Shihua Lin;Michael Yifei Du;Xia Li;Yun Xiao;Yunpeng Zhang |
| 8 | Molecular characterization and clinical relevance of m(6)A regulators across 33 cancer types | 期刊论文 | Li Yongsheng;Xiao Jun;Bai Jing;Tian Yi;Qu Yinwei;Chen Xiang;Wang Qi;Li Xinhui;Zhang Yunpeng;Xu Juan |
| 9 | Comprehensive Characterization of Somatic Mutations Impacting lncRNA Expression for Pan-Cancer | 期刊论文 | Yue Gao;Xin Li;Hui Zhi;Yunpeng Zhang;Peng Wang;Yanxia Wang;Shipeng Shang;Ying Fang;Weitao Shen;Shangwei Ning;Steven Xi Chen;Xia Li |
| 10 | 癌症风险非编码(lncRNA/miRNA)标志物识别及其协同调控功能研究 | 奖励 | 李霞;张云鹏;王鹏;宁尚伟;白静 |
| 11 | 癌症风险非编码RNA识别的关键技术及应用 | 奖励 | 李霞;宁尚伟;张云鹏;王鹏;白静;许艳军;李峰 |
| 12 | LncRNAs2Pathways: Identifying the pathways influenced by a set of lncRNAs of interest based on a global network propagation method | 期刊论文 | Han Junwei;Liu Siyao;Sun Zeguo;Zhang Yunpeng;Zhang Fan;Zhang Chunlong;Shang Desi;Yang Haixiu;Su Fei;Xu Yanjun;Li Chunquan;Ren Huan;Li Xia |
| 13 | RNAactDrug: a comprehensive database of RNAs associated with drug sensitivity from multi-omics data | 期刊论文 | Qun Dong;Feng Li;Yanjun Xu;Jing Xiao;Yingqi Xu;Desi Shang;Chunlong Zhang;Haixiu Yang;Zishan Wang;Kai Mi;Xia Li;Yunpeng Zhang |
| 14 | Gain-of-Function Mutations: An Emerging Advantage for Cancer Biology | 期刊论文 | Li Yongsheng;Zhang Yunpeng;Li Xia;Yi Song;Xu Juan |
| 15 | FACER: comprehensive molecular and functional characterization of epigenetic chromatin regulators | 期刊论文 | Jianping Lu;Juan Xu;Junyi Li;Tao Pan;Jing Bai;liqiang Wang;Xiyun Jin;Xiaoyu Lin;Yunpeng Zhang;Yongsheng Li;Nidhi Sahni;Xia Li |
| 16 | Systematic identification of lincRNA-based prognostic biomarkers by integrating lincRNA expression and copy number variation in lung adenocarcinoma | 期刊论文 | Wang Li;Zhao Hongying;Xu Yingqi;Li Jing;Deng Chunyu;Deng Yulan;Bai Jing;Li Xia;Xiao Yun;Zhang Yunpeng |
| 17 | BioM2MetDisease: a manually curated database for associations between microRNAs, metabolites, small molecules and metabolic diseases | 期刊论文 | Xu Yanjun;Yang Haixiu;Wu Tan;Dong Qun;Sun Zeguo;Shang Desi;Li Feng;Xu Yingqi;Su Fei;Liu Siyao;Zhang Yunpeng;Li Xia |
| 18 | LncMAP: Pan-cancer atlas of long noncoding RNA-mediated transcriptional network perturbations | 期刊论文 | Yongsheng Li;Lili Li;Zishan Wang;Tao Pan;Nidhi Sahni;Xiyun Jin;Guangjuan Wang;Junyi Li;Xiangyi Zheng;Yunpeng Zhang;Juan Xu;Song Yi;Xia Li |
| 19 | Identification and comprehensive characterization of lncRNAs with copy number variations and their driving transcriptional perturbed subpathways reveal functional significance for cancer | 期刊论文 | Yanjun Xu;Tan Wu;Feng Li;Qun Dong;Jingwen Wang;Desi Shang;Yingqi Xu;Chunlong Zhang;Yiying Dou;Congxue Hu;Haixiu Yang;Xuan Zheng;Yunpeng Zhang;Lihua Wang;Xia Li |
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