恶性肿瘤关键突变介导的circRNA-lncRNA-miRNA多层次调控网络扰动模型构建及分析研究
31871338
2018
C0608.生物数据资源与分析方法
徐娟
面上项目
教授
哈尔滨医科大学
59万元
数据整合;网络构建;多特征融合;系统生物学;人
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 生物医学研究的统计方法(第二版) | 专著 | 徐娟 |
| 2 | Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers | 期刊论文 | Li Yongsheng;Jiang Tiantongfei;Zhou Weiwei;Li Junyi;Li Xinhui;Wang Qi;Jin Xiaoyan;Yin Jiaqi;Chen Liuxin;Zhang Yunpeng;Xu Juan;Li Xia |
| 3 | Molecular characterization and clinical relevance of m(6)A regulators across 33 cancer types | 期刊论文 | Li Yongsheng;Xiao Jun;Bai Jing;Tian Yi;Qu Yinwei;Chen Xiang;Wang Qi;Li Xinhui;Zhang Yunpeng;Xu Juan |
| 4 | 医工结合,创建生物信息学专业人才培养模式 | 奖励 | 李霞;徐娟;李永生;张云鹏;肖云;白静 |
| 5 | 基于生物数据融合的恶性肿瘤中miRNA-ceRNA复合协同调控模式的研究 | 奖励 | 徐娟;王理;李永生;赵红颖 |
| 6 | SurvivalMeth: a web server to investigate the effect of DNA methylation-related functional elements on prognosis | 期刊论文 | Zhang Chunlong;Zhao Ning;Zhang Xue;Xiao Jun;Li Junyi;Lv Dezhong;Zhou Weiwei;Li Yongsheng;Xu Juan;Li Xia |
| 7 | ImmReg: the regulon atlas of immune-related pathways across cancer types | 期刊论文 | Jiang Tiantongfei;Zhou Weiwei;Chang Zhenghong;Zou Haozhe;Bai Jing;Sun Qisen;Pan Tao;Xu Juan;Li Yongsheng;Li Xia |
| 8 | TransLnc: a comprehensive resource for translatable lncRNAs extends immunopeptidome | 期刊论文 | Dezhong Lv;Zhenghong Chang;Yangyang Cai;Junyi Li;Liping Wang;Qiushuang Jiang;Kang Xu;Na Ding;Xia Li;Juan Xu;Yongsheng Li |
| 9 | A time-resolved proteotranscriptomics atlas of the human placenta reveals pan-cancer immunomodulators | 期刊论文 | Ding Na;Zhang Botao;Ying Wantao;Song Jie;Feng Lin;Zhang Kaitai;Li Hongxia;Xu Juan;Xiao Ting;Cheng Shujun |
| 10 | 非编码RNA基因协同调控作用的预测方法 | 专利 | 李永生;李霞;徐娟 |
| 11 | 整合免疫肽组数据识别非编码区域的免疫表位的鉴定方法 | 专利 | 徐娟;李永生;潘涛 |
| 12 | Landscape of Enhancer-Enhancer Cooperative Regulation during Human Cardiac Commitment | 期刊论文 | Chen Hong;Xiao Jun;Shao Tingting;Wang Li;Bai Jing;Lin Xiaoyu;Ding Na;Qu Yinwei;Tian Yi;Chen Xiang;Liu Hui;Liu Hongyu;Xu Juan;Li Xia |
| 13 | LncSpA: LncRNA Spatial Atlas of Expression across Normal and Cancer Tissues | 期刊论文 | Lv Dezhong;Xu Kang;Jin Xiyun;Li Junyi;Shi Yuchen;Zhang Mengying;Jin Xiaoyan;Li Yongsheng;Xu Juan;Li Xia |
| 14 | IEAtlas: an atlas of HLA-presented immune epitopes derived from non-coding regions | 期刊论文 | Yangyang Cai;Dezhong Lv;Donghao Li;Jiaqi Yin;Yingying Ma;Ya Luo;Limei Fu;Na Ding;Yongsheng Li;Zhenwei Pan;Xia Li;Juan Xu |
| 15 | CeRNASeek: an R package for identification and analysis of ceRNA regulation | 期刊论文 | Zhang Mengying;Jin Xiyun;Li Junyi;Tian Yi;Wang Qi;Li Xinhui;Xu Juan;Li Yongsheng;Li Xia |
| 16 | 2019年度“长江学者奖励计划”青年学者 | 奖励 | 徐娟 |
| 17 | Pan-cancer characterization of expression and clinical relevance of m6A-related tissue-elevated long non-coding RNAs | 期刊论文 | Kang Xu;Yangyang Cai;Mengying Zhang;Haozhe Zou;Zhenghong Chang;Donghao Li;Jing Bai;Juan Xu;Yongsheng Li |
| 18 | Computational Epigenetics and Diseases | 专著 | Juan Xu;Yongsheng Li;Tingting Shao |
| 19 | PRES: a webserver for decoding the functional perturbations of RNA editing sites | 期刊论文 | Dezhong Lv;Kang Xu;Changbo Yang;Yujie Liu;Ya Luo;Weiwei Zhou;Haozhe Zou;Yangyang Cai;Na Ding;Xia Li;Tingting Shao;Yongsheng Li;Juan Xu |
| 20 | 一种识别非编码RNA多肽的方法 | 专利 | 海南医学院;哈尔滨医科大学 |
| 21 | “科教融合、全程多元、知行合一”的生物信息学专业创新教学体系研究与实践 | 奖励 | 徐娟;李永生;张云鹏;邵婷婷;李霞 |
| 22 | Gain-of-function mutations: an emerging advantage for cancer biology | 期刊论文 | Yongsheng Li;Yunpeng Zhang;Xia Li;Song Yi;Juan Xu |
| 23 | Surveying lncRNA-lncRNA cooperations reveals dominant effect on tumor immunity cross cancers | 期刊论文 | Tingting Shao;Yunjin Xie;Jingyi Shi;Changbo Yang;Haozhe Zou;Yongsheng Li;Juan Xu;Xia Li |
| 24 | MIR22HG acts as a tumor suppressor via TGF beta/SMAD signaling and facilitates immunotherapy in colorectal cancer | 期刊论文 | Xu Juan;Shao Tingting;Song Mingxu;Xie Yunjin;Zhou Jialiang;Yin Jiaqi;Ding Na;Zou Haozhe;Li Yongsheng;Zhang Jiwei |
| 25 | Shedding light on the hidden human proteome expands immunopeptidome in cancer | 期刊论文 | Yongsheng Li;Yunpeng Zhang;Tao Pan;Ping Zhou;Weiwei Zhou;Yueying Gao;Shaojiang Zheng;Juan Xu |
| 26 | A Novel Approach to Identify Enhancer lincRNAs by Integrating Genome, Epigenome, and Regulatome | 期刊论文 | Liu Hui;Jiang Tiantongfei;Wang Shuyuan;Chen Xiang;Jin Xiaoyan;Wang Qi;Li Xinhui;Yin Jiaqi;Shao Tingting;Li Yongsheng;Xu Juan;Wu Qiong |
| 27 | Complex impact of DNA methylation on transcriptional dysregulation across 22 human cancer types | 期刊论文 | Wang Zishan;Yin Jiaqi;Zhou Weiwei;Bai Jing;Xie Yunjin;Xu Kang;Zheng Xiangyi;Xiao Jun;Zhou Li;Qi Xiaolin;Li Yongsheng;Li Xia;Xu Juan |
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