基于免疫调控的山豆根治疗乙型肝炎的作用机制及物质基础研究
81330090
2013
H32.中药学
肖小河
重点项目
研究员
中国人民解放军总医院
290万元
山豆根;物质基础;慢性乙型肝炎;清热解毒;免疫调控
2014-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 一种药物组合物及其用途 | 专利 | 王伽伯;肖小河;刘振杰;李朋彦 |
| 2 | 基于生物靶标网络分析的山豆根抗乙肝病毒的作用机制初步研究 | 期刊论文 | 柴煊;孟雅坤;柏兆方;张雅铭;肖小河;牛明 |
| 3 | Oxymatrine attenuates CCl4-induced hepatic fibrosis via modulation of TLR4-dependent inflammatory and TGF-beta 1 signaling pathways | 期刊论文 | Zhao Hong-wei;Zhang Zhen-fang;Chai Xuan;Li Guang-quan;Cui He-rong;Wang Hong-bo;Meng Ya-kun;Liu Hui-min;Wang Jia-bo;Li Rui-sheng;Bai Zhao-fang;Xiao Xiao-he |
| 4 | 五味子甲素对NLRP3炎性小体活性的抑制作用及机制初步研究 | 期刊论文 | 崔鹤蓉;李朋彦;李雨萌;王睿林;何娟娟;桑秀秀;蔡光明;牛明;王伽伯;柏兆方;肖小河 |
| 5 | Inhibition of Sophocarpine on Poly I. C/D-GaIN-Induced Immunological Liver Injury in Mice | 期刊论文 | Huang Yin-Qiu;Zhou Hou-Qin;Yang Zhi-Rui;Huang Yin-Qiu;Zhou Hou-Qin;Yang Zhi-Rui;Zhao Yan-Ling;Li Peng-Yan;Wang Jia-Bo;Bai Zhao-Fang;Xiao Xiao-He;Yang Rui-Chuang;Wang Li-Fu;Li Jian-Yu;Liu Hong-Hong;Zhao YL;Xiao XH |
| 6 | Sophocarpine Protects Mice from ConA-Induced Hepatitis via Inhibition of the IFN-Gamma/STAT1 Pathway | 期刊论文 | Sang Xiu-Xiu;Zhang Cong-En;Shen Hong-Hui;Guo Yu-Ming;Zhang Ya-Ming;Niu Ming;Wang Jia-Bo;Bai Zhao-Fang;Xiao Xiao-He;Wang Rui-Lin;Liu Shi-Jing;Wang JB;Bai ZF;Xiao XH |
| 7 | Efficacy of Compound Kushen Injection in Relieving Cancer-Related Pain: A Systematic Review and Meta-AnalysisAnti-hepatitis B virus effect of matrine-type alkaloid and involvement of p38 mitogen-activated protein kinase and tumor necrosis factor receptor-associated factor 6 | 期刊论文 | Yu-ming Guo;Yi-xue Huang;Hong-hui Shen;Xiu-xiu Sang;Xiao Ma;Yan-ling Zhao;Xiao-he Xiao |
| 8 | Kushenin Combined with Nucleos(t)ide Analogues for Chronic Hepatitis B: A Systematic Review and Meta-Analysis | 期刊论文 | Chen Zhe;Ma Xiao;Zhao Yanling;Wang Jiabo;Zhang Yaming;Zhu Yun;Wang Lifu;Chen Chang;Wei Shizhang;Yang Zhirui;Gong Man;Shen Honghui;Bai Zhaofang;Guo Yuming;Niu Ming;Xiao Xiaohe |
| 9 | Chinese herbal extract Su-duxing had potent inhibitory effects on both wild-type and entecavir-resistant hepatitis B virus (HBV) in vitro and effectively suppressed HBV replication in mouse model. | 期刊论文 | Liu Yan;Yao Weiming;Si Lanlan;Hou Jun;Wang Jiabo;Xu Zhihui;Li Weijie;Chen Jianhong;Li Ruisheng;Li Penggao;Bo Lvping;Xiao Xiaohe;Lan Jinchu;Xu Dongping |
| 10 | Anti-hepatitis B virus effect of matrine-type alkaloid and involvement of p38 mitogen-activated protein kinase and tumor necrosis factor receptor-associated factor 6. | 期刊论文 | Chen Jia-Xin;Shen Hong-Hui;Niu Ming;Guo Yu-Ming;Liu Xiao-Qiong;Han Yan-Zhong;Zhang Ya-Ming;Zhao Yan-Ling;Bai Bing-Ke;Zhou Wen-Jun;Xiao Xiao-He |
| 11 | T cell–associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model | 期刊论文 | Xiuxiu Sang;Ruilin Wang;Yanzhong Han;Cong’en Zhang;Honghui Shen;Zhirui Yang;Yin Xiong;Huimin Liu;Shijing Liu;Ruisheng Li;Ruichuang Yang;Jiabo Wang;Xuejun Wang;Zhaofang Bai;Xiaohe Xiao |
| 12 | 复方苦参注射液治疗癌性疼痛的系统评价 | 期刊论文 | 黄奕雪;郭玉明;桑秀秀;沈宏辉;马骁;刘士敬;肖小河 |
| 13 | 氧化苦参碱通过免疫调节保护刀豆蛋白A诱导的小鼠免疫性肝损伤 | 期刊论文 | 桑秀秀;王睿林;韩延忠;崔鹤蓉;尹萍;贺兰芝;刘慧敏;刘士敬;肖小河;柏兆方 |
| 14 | 乙型肝炎病毒相关慢加急性肝衰竭中西医药物治疗概况 | 期刊论文 | 王仲霞;李筠;李永纲;王立福;宫嫚;肖小河 |
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