【60831004】轻度认知损害及阿尔茨海默病的多模态脑影像研究和早期诊断系统国家自然基金项目

轻度认知损害及阿尔茨海默病的多模态脑影像研究和早期诊断系统

项目批准号： 60831004

批准年份： 2008

学科分类： F0116.图像信息处理

项目负责人：张熙

资助类别：重点项目

负责人职称：主任医师

依托单位：中国人民解放军总医院

资助金额： 180万元

关键词：生物标记;辅助诊断系统;事件相关电位（ERP）;轻度认知损害（MCI）;多模态磁共振影像

起止时间： 2009-01-01到2012-12-31

中英文摘要
结题摘要
结题报告
项目成果
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序号	标题	类型	作者
1	蒙特利尔认知评价量表(中文版)在轻度认知损害诊断及进展过程中的作用	期刊论文	王盼\|张熙\|周波\|张增强\|WANG Pan, ZHANG Xi, ZHOU Bo, ZHANG Zeng-qiang Depa\|
2	Altered spontaneous activity in anisometropic amblyopia subjects: revealed by resting-state FMRI	期刊论文	X. Lin\|K. Ding\|Y. Liu\|X. Yan\|S. Song\|T. Jiang\|
3	Altered Grey Matter Volumes and Functional Connectivity pattern in hippocampus in AD and MCI	期刊论文	Y. Liu\|Y. Guo\|X. Zhang\|B. Zhou\|Z. Zhang\|X. Zhang\|T. Jiang\|
4	静息态功能磁共振观察阿尔兹海默病患者丘脑功能连接特点	期刊论文	周波\|张增强\|安宁豫\|姚洪祥\|王盼\|高广生\|王鲁宁\|张熙\|
5	Identification of conversion from mild cognitive impairment to Alzheimer's disease using multivariate predictors	期刊论文	Y. Cui\|J. S. Jin\|B. Liu\|S. Luo\|X. Zhen\|M. Fan\|T. Liu\|W. Zhu\|M. Park\|T. Jiang\|
6	Altered spontaneous activity in Alzheimer's disease and mild cognitive impairment revealed by Regional Homogeneity	期刊论文	张熙\|
7	关注中老年工作人群的睡眠问题	期刊论文	张熙\|
8	Age of onset of blindness affects brain anatomical networks constructed using diffusion tensor tractography	期刊论文	J. Li\|Y. Liu\|W. Qin\|J. Jiang\|Z. Qiu\|J. Xu\|C. Yu\|T. Jiang\|
9	遗忘型轻度认知损害与阿尔茨海默病的脑影像结构特点研究. 遗忘型轻度认知损害与阿尔茨海默病的脑影像结构特点研究	期刊论文	戴海涛\|张熙\|
10	IMPAIRED THALAMUS CONNECTIVITY PATTERN IN ALZHEIMER’S DISEASE AND MILD COGNITIVE IMPAIRMENT: A RESTING STATE FMRI STUDY	会议论文	B. Zhou\|Y. Liu\|X. Zhang\|T. Jiang\|
11	遗忘型轻度认知损害患者海马三维磁共振影像特点	期刊论文	邢建丽；张熙；王鲁宁；周波；管锦群；安宁豫；程流泉；张远超\|
12	Discriminant Analysis of Resting-state Functional Connectivity Patterns on the Grassmann Manifold	会议论文	Y. Fan\|Y. Liu\|T. Z. Jiang\|Z. N. Liu\|Y. H. Hao\|H. H. Liu\|
13	Altered spontaneous activity in Alzheimer's disease and mild cognitive impairment revealed by Regional Homogeneity	期刊论文	Z. Zhang\|X. Zhang\|Y. Liu\|T. Jiang\|B. Zhou\|N. An\|H. Dai\|P. Wang\|Y. Niu\|L. Wang\|
14	A Riemannian framework for orientation distribution function computing	会议论文	J. Cheng\|A. Ghosh\|T. Jiang\|R. Deriche\|
15	Neurofunctional information extraction from early 11C-PIB frames	期刊论文	L. Liu\|L. Fu\|X. Zhang\|B. Zhou\|Y. Liu\|X. Zhang\|J. Tian\|Y. Fan\|
16	A functional MRI evaluation of frontal dysfunction in patients with severe obstructive sleep apnea	期刊论文	张熙\|
17	遗忘型轻度认知损害与阿尔茨海默病的脑影像结构特点研究	期刊论文	戴海涛\|张熙\|
18	老年人脑干梗死与椎-基底动脉供血不足的病例回顾研究	期刊论文	管锦群\|王鲁宁\|王振福\|孙鹏\|高峰\|张熙\|
19	Local Label Learning (LLL) for Multi-Atlas based Segmentation	期刊论文	Y. Hao\|J. Liu\|C. Yu\|X. Zhang\|T. Jiang\|
20	Impaired Functional Connectivity of Thalamus in Alzheimer’s Disease and Mild Cognitive Impairment: a Resting-State fMRI Study	期刊论文	B. Zhou\|Y. Liu\|X. Zhang\|T. Jiang\|
21	Mapping white matter and gray matter changes through the course of Alzheimer’s disease	期刊论文	X. Sui\|C. Yu\|X. Zhang\|T. Jiang\|
22	Impaired Long Distance Functional Connectivity and Weighted Network Architecture in Alzheimer's Disease	期刊论文	Y. Liu\|E. Bullmore\|C. Yu\|X. Zhang\|J. Liu\|Y. Duan\|A. F. Alex\|er-Bloch\|B. Liu\|T. Jiang\|
23	Lack of association between white matter integrity and DISC1 Ser704Cys in a large sample of healthy Han Chinese individuals	期刊论文	Bing Liu\|Yong Hui Li\|Bing Hou\|Chun Shui Yu\|T. Z. Jiang\|
24	阿尔茨海默病斑块显像:新型放射性示踪剂~(18)F-W372在体试验初探	期刊论文	富丽萍\|张锦明\|王盼\|张增强\|尹大一\|张熙\|陈英茂\|田嘉禾\|
25	遗忘型轻度认知损害的海马三维磁共振影像特点	期刊论文	邢建丽\|张熙\|王鲁宁\|周波\|管锦群\|安宁豫\|程流泉\|张远超\|
26	静息态功能磁共振成像观察阿尔茨海默病患者大脑自发活动特点	期刊论文	张增强\|周波\|王盼\|张熙\|
27	蒙特利尔认知评估量表的验证性因素分析	期刊论文	王盼\|张熙\|周波\|张增强\|WANG Pan,ZHANG Xi,ZHOU Bo,et al(Department of Geri\|
28	神经系统变性疾病与快速眼动期睡眠行为异常	期刊论文	何荆贵\|张熙\|
29	Dynamic Cortical Thinning in Alzheimer's disease with hypertension	期刊论文	B. Hou\|L. Gao\|B. Liu\|T. Jiang\|
30	神经系统疾病与RBD	会议论文	张熙\|
31	Perceptual and response interference in Alzheimer’s disease and mild cognitive impairment	期刊论文	P. Wang\|X. Zhang\|Y. Liu\|B. Zhou\|X. Zhang\|T. Jiang\|
32	Functional Connectivity of New Supplement of Limbic System, Marginal Division, Affected in Alzheimer’s Disease	期刊论文	Z. Zhang\|Y. Liu\|X. Zhang\|T. Jiang\|
33	Altered brain connectome in Alzheimer’s disease revealed by Functional Connectivity Density Mapping	期刊论文	X. Sui\|M. Zhu\|Y. Cui\|X. Zhang\|C. Yu\|T. Jiang\|
34	Decreased Functional Connectivity of the Amygdala in Alzheimer’s disease Revealed by Resting-state fMRI	期刊论文	H. Yao\|Y. Liu\|B. Zhou\|X. Zhang\|T. Jiang\|
35	White matter abnormalities in major depression: a tract-based spatial statistics and rumination study	期刊论文	N. Zuo\|T. Jiang\|J. Fang\|X. Lv\|Y. Zhou\|Y. Hong\|T. Li\|H. Tong\|X. Wang\|W. Wang\|
36	Identification of conversion from mild cognitive impairment to Alzheimer's disease using multivariate predictors	期刊论文	蒋田孖\|
37	高血压相关脑白质损伤的磁共振弥散张量研究	期刊论文	管锦群\|张熙\|蒋田仔\|安宁豫\|王鲁宁\|王奇峰\|GUAN Jin-qun,ZHANG Xi,JIANG Tian-zi,et al(Departme\|
38	静息态功能磁共振观察阿尔茨海默病患者丘脑功能连接特点	期刊论文	周波\|张熙\|
39	Disrupted small-world brain networks in moderate Alzheimer's disease: a resting-state FMRI study	期刊论文	X. Zhao\|Y. Liu\|X. Wang\|B. Liu\|Q. Xi\|Q. Guo\|H. Jiang\|T. Jiang\|P. Wang\|
40	轻度认知功能障碍的磁共振弥散张量成像研究	期刊论文	管锦群\|张熙\|
41	Discriminant Analysis of Resting-state Functional Connectivity Patterns on the Grassmann Manifold	会议论文	Y. Fan\|Y. Liu\|T. Z. Jiang\|Z. N. Liu\|Y. H. Hao\|H. H. Liu\|

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