NOX4/Nrf2失衡诱导线粒体自噬过度激活在PM2.5诱发慢阻肺急性加重中的作用机制

81870030
2018
H0105.慢性阻塞性肺疾病
彭丽萍
面上项目
教授
吉林大学
60万元
细颗粒物;线粒体自噬;慢阻肺急性加重;NOX4/Nrf2氧化失衡
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Hyperoside relieves particulate matter-induced lung injury by inhibiting AMPK/mTOR-mediated autophagy deregulation 期刊论文 Gao Yun;Fan Xiao;Gu wenjing;Ci Xinxin;Peng Liping
2 Pterostilbene prevents LPS-induced early pulmonary fibrosis by suppressing oxidative stress, inflammation and apoptosis in vivo 期刊论文 Yang Huahong;Hua Cong;Yang Xiaolin;Fan Xiaoye;Song Hongyu;Peng Liping;Ci Xinxin
3 Oridonin Sensitizes Cisplatin-Induced Apoptosis via AMPK/Akt/mTOR-Dependent Autophagosome Accumulation in A549 Cells 期刊论文 Yang Huahong;Gao Yun;Fang Xiaoye;Liu Xingkai;Peng Liping;Ci Xinxin
4 Isoliquiritigenin exerts antioxidative and anti-inflammatory effects via activating the KEAP-1/Nrf2 pathway and inhibiting the NF-κB and NLRP3 pathways in carrageenan-induced pleurisy 期刊论文 Gao Yun;Lv Xiaohong;Yang Huahong;Peng Liping;Ci Xinxin
5 Leonurine inhibits the TXNIP/NLRP3 and NF-κB pathways via Nrf2 activation to alleviate carrageenan-induced pleurisy in mice 期刊论文 Yan Kun;Hu Jianqiang;Hou Tianhua;Ci Xinxin;Peng Liping
6 PM2.5 inhibits system Xc- activity to induce ferroptosis by activating the AMPK-Beclin1 pathway in acute lung injury 期刊论文 Yan Kun;Hou Tianhua;Zhu Laiyu;Ci Xinxin;Peng Liping
7 Amentoflavone Ameliorates Carrageenan-Induced Pleurisy and Lung Injury by Inhibiting the NF-κB/ STAT3 Pathways via Nrf2 Activation 期刊论文 Hou Tianhua;Yang Manshi;Yan Kun;Fan Xiaoye;Ci Xinxin;Peng Liping
8 Oridonin attenuates carrageenan‑induced pleurisy via activation of the KEAP‑1/Nrf2 pathway and inhibition of the TXNIP/NLRP3 and NF‑κB pathway in mice 期刊论文 Yang Huahong;Huang Jinbo;Gao Yanli;Wen Zhongmei;Peng Liping;Ci Xinxin
9 Oridonin protects LPS-induced acute lung injury by modulating Nrf2-mediated oxidative stress and Nrf2-independent NLRP3 and NF-κB pathways 期刊论文 Yang Huahong;Lv Hongming;Li Haijun;Ci Xinxin;Peng Liping
10 Oridonin attenuates LPS-induced early pulmonary fibrosis by regulating impaired autophagy, oxidative stress, inflammation and EMT 期刊论文 Yang Huahong;Wang Lidong;Yang Manshi;Hu Jiangqiang;Zhang Erli;Peng Liping
11 PM2.5 increases susceptibility to acute exacerbation of COPD via NOX4/Nrf2 redox imbalance-mediated mitophagy 期刊论文 Fan Xiaoye;Dong Tingting;Yan Kun;Ci Xinxin;Peng Liping
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