基于机器学习的酶催化剂立体选择性的调控与多手性精准合成

91956128
2019
B0111.仿生与绿色合成
吴起
重大研究计划
教授
浙江大学
75万元
蛋白质工程;立体选择性;生物催化反应;机器学习;蛋白质理性设计
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 Rational design of fatty acid photodecarboxylase enables the efficient decarboxylation of medium- and short-chain fatty acids for the production of gasoline bio-alkanes 期刊论文 徐维华;陈杨;李丹阳;王志国;徐鉴;吴起
2 Photoinduced Promiscuity of Cyclohexanone Monooxygenase for the Enantioselective Synthesis of α‐Fluoroketones 期刊论文 彭永珍;王志国;陈杨;徐维华;胡玉静;陈志春;徐鉴;吴起
3 Synthesis of 1,2,3,4‐Tetrahydroisoquinolines via Palladium‐Catalyzed Cyclization of N ‐Tosylhydrazones with ortho‐Bromophenethyl Tosylamides 期刊论文 张洁明;张展鸣;吴起;张俊良
4 Recent Advances in Photobiocatalysis for Selective Organic Synthesis 期刊论文 彭永珍;陈志春;徐鉴;吴起
5 Deracemization of racemic alcohols combining photooxidation and biocatalytic reduction 期刊论文 王剑锋;彭永珍;徐鉴;吴起
6 Intramolecular Stereoselective Stetter Reaction Catalyzed by Benzaldehyde Lyase 期刊论文 陈晓阳;王志国;楼玉姣;彭永珍;朱巧燕;徐鉴;吴起
7 The mutagenesis of a single site for enhancing or reversing the enantio- or regiopreference of cyclohexanone monooxygenases 期刊论文 胡玉静;徐维华;惠成功;徐鉴;黄美兰;林贤福;吴起
8 Double Enzyme-Catalyzed One-Pot Synthesis of Enantiocomplementary Vicinal Fluoro Alcohols 期刊论文 范嘉杰;彭永珍;徐维华;王安林;徐鉴;郁惠蕾;林贤福;吴起
9 Enantiocomplementary C-H Bond Hydroxylation Combining Photo-Catalysis and Whole-Cell Biocatalysis in a One-Pot Cascade Process 期刊论文 彭永珍;李丹阳;范嘉杰;徐维华;徐鉴;郁慧蕾;林贤福;吴起
10 Engineering Fatty Acid Photodecarboxylase to Enable Highly Selective Decarboxylation of trans Fatty Acids 期刊论文 李丹阳;韩涛;薛佳丹;徐维华;徐鉴;吴起
11 Electronic Effect‐Guided Rational Design of Candida antarctica Lipase B for Kinetic Resolution Towards Diarylmethanols 期刊论文 李丹阳;楼玉姣;徐鉴;陈晓阳;林贤福;吴起
12 Substrate Engineering in Lipase-Catalyzed Selective Polymerization of d-/l-Aspartates and Diols to Prepare Helical Chiral Polyester. 期刊论文 张瑜;夏波;李炎炎;林贤福;吴起
13 Focused rational iterative site-specific mutagenesis (FRISM) 期刊论文 李丹阳;吴起;Reetz Manfred T
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享