去泛素化修饰酶新靶标的体内捕获、功能解析和化学干预手段的研发

91753139
2017
C0702.细胞信号转导
张龙
重大研究计划
教授
浙江大学
70万元
DUB探针;非天然氨基酸;共价肽键;去泛素化酶
2018-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 The interactions between cGAS-STING pathway and pathogens 期刊论文 Cheng Z;Dai T;He X;Zhang Z;Xie F;Wang S;Zhang L;Zhou F
2 Extracellular Vesicles in Cancer Immune Microenvironment and Cancer Immunotherapy 期刊论文 Xie F;Zhou X;Fang M;Li H;Tu Y;Su P;Zhang L;Zhou F
3 Coronavirus in Continuous Flux: From SARS-CoV to SARS-CoV-2 期刊论文 Dong Y;Dai T;Liu J;Zhang L;Zhou F
4 The Functional Deubiquitinating Enzymes in Control of Innate Antiviral Immunity 期刊论文 Zong Z;Zhang Z;Wu L;Zhang L;Zhou F
5 FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral Infection 期刊论文 Dai T;Wu L;Wang S;Wang J;Xie F;Zhang Z;Fang X;Li J;Fang P;Li F;Jin K;Dai J;Yang B;Zhou F;van Dam H;Cai D;Huang H;Zhang L
6 Exosomes in head and neck cancer: Roles, mechanisms and applications 期刊论文 Cao J;Zhang M;Xie F;Lou J;Zhou X;Zhang L;Fang M;Zhou F
7 Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity 期刊论文 Zhang Z;Fang X;Wu X;Ling L;Chu F;Li J;Wang S;Zang J;Zhang B;Ye S;Zhang L;Yang B;Lin S;Huang H;Wang A;Zhou F
8 The function and clinical application of extracellular vesicles in innate immune regulation 期刊论文 Zhou X;Xie F;Wang L;Zhang L;Zhang S;Fang M;Zhou F
9 OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ 期刊论文 Zhang Z;Du J;Wang S;Shao L;Jin K;Li F;Wei B;Ding W;Fu P;van Dam H;Wang A;Jin J;Ding C;Yang B;Zheng M;Feng X;Guan K;Zhang L
10 Non-coding RNA in thyroid cancer - Functions and mechanisms 期刊论文 Cao J;Zhang M;Lou J;Zhang L;Zhou F;Fang M
11 An effective platform for cancer immunotherapy: pooled knockin targeting for genome engineering 期刊论文 Jin K;Zhang L;Zhou F
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