癫痫异常网络导致认知行为障碍的分子基础
91332202
2013
H0902.意识障碍与认知功能障碍
陈忠
重大研究计划
教授
浙江大学
300万元
癫痫网络;海马环路;白介素1β;颞叶癫痫;认知功能障碍
2014-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Interictal ripples nested in epileptiform discharge help to identify the epileptogenic zone in neocortical epilepsy | 期刊论文 | Wang Shuang;So Norman K.;Jin Bo;Wang Irene Z.;Bulacio Juan C.;Enatsu Rei;Dai Shenyi;Chen Zhong;Gonzalez-Martinez Jorge;Najm Imad M. |
| 2 | Transient increase of interleukin-1 beta after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling | 期刊论文 | Feng Bo;Tang Yangshun;Chen Bin;Xu Cenglin;Wang Yi;Dai Yunjian;Wu Dengchang;Zhu Junmin;Wang Shuang;Zhou Yudong;Shi Liyun;Hu Weiwei;Zhang Xia;Chen Zhong |
| 3 | A decrease of ripples precedes seizure onset in mesial temporal lobe epilepsy | 期刊论文 | Xu Cenglin;Wang Shuang;Wang Yi;Lin Kang;Pan Gang;Xu Zhenghao;Gonzalez-Martinez Jorge;Gao Feng;Wu Xiaohua;Zhang Shihong;Bulacio Juan C.;Najm Imad M.;Luo Jianhong;Hu Weiwei;Wu Zhaohui;So Norman K.;Chen Zhong |
| 4 | INTERLEUKIN-1 RECEPTOR IS A TARGET FOR ADJUNCTIVE CONTROL OF DIAZEPAM-REFRACTORY STATUS EPILEPTICUS IN MICE | 期刊论文 | Xu Zheng-Hao;Wang Yi;Tao An-Feng;Yu Jie;Wang Xiao-Yu;Zu Yun-Yun;Zhang Shi-Hong;Chen Zhong |
| 5 | Generation of Febrile Seizures and Subsequent Epileptogenesis | 期刊论文 | Feng Bo;Chen Zhong |
| 6 | The Pro-inflammatory Cytokine Interleukin-1 is a Key Regulatory Factor for the Postictal Suppression in Mice | 期刊论文 | Tao An-Feng;Xu Zheng-Hao;Chen Bin;Wang Yi;Wu Xiao-Hua;Zhang Jing;Tang Yang-Shun;Xu Ceng-Lin;Zhao Hua-Wei;Hu Wei-Wei;Shi Li-Yun;Zhang Shi-Hong;Chen Zhong |
| 7 | Entorhinal Principal Neurons Mediate Brain-stimulation Treatments for Epilepsy | 期刊论文 | Zhenghao Xu;Yi Wang;Bin Chen;Cenglin Xu;Ying Wang;Shihong Zhang;Weiwei Hu;Shuang Wang;Yi Guo;Xiangnan Zhang;Jianhong Luo;Shumin Duan;Zhong Chen |
| 8 | Electroresponsive Nanoparticles Improve Antiseizure Effect of Phenytoin in Generalized Tonic-Clonic Seizures | 期刊论文 | Wang Yi;Ying Xiaoying;Chen Liying;Liu Yao;Wang Ying;Liang Jiao;Xu Cenglin;Guo Yi;Wang Shuang;Hu Weiwei;Du Yongzhong;Chen Zhong |
| 9 | Low-frequency stimulation of the primary focus retards positive transfer of secondary focus | 期刊论文 | Kuang Yifang;Xu Cenglin;Zhang Yinxi;Wang Yi;Wu Xiaohua;Wang Ying;Liu Yao;Zhong Kai;Cheng Hui;Guo Yi;Wang Shuang;Ding Meiping;Chen Zhong |
| 10 | Angiopep-Conjugated Electro-Responsive Hydrogel Nanoparticles: Therapeutic Potential for Epilepsy | 期刊论文 | Ying Xiaoying;Wang Yi;Liang Jiao;Yue Jiaxing;Xu Cenglin;Lu Lina;Xu Zhenghao;Gao Jianqing;Du Yongzhong;Chen Zhong |
| 11 | Widespread pain sensitization after partial infraorbital nerve transection in MRL/MPJ mice | 期刊论文 | Zhang Shi-Hong;Yu Jie;Lou Guo-Dong;Tang Ying-Ying;Wang Ran-Ran;Hou Wei-Wei;Chen Zhong |
| 12 | Early hypoactivity of hippocampal rhythms during epileptogenesis after prolonged febrile seizures in freely-moving rats | 期刊论文 | Feng Bo;Tang Yang-Shun;Chen Bin;Xu Zheng-Hao;Wang Yi;Wu Deng-Chang;Zhao Hua-Wei;Zhang Shi-Hong;Chen Zhong |
| 13 | Protective effect of carnosine on febrile seizures in immature mice | 期刊论文 | Dai Yun-Jian;Wu Deng-Chang;Feng Bo;Hou Wei-wei;Xu Ceng-Lin;Ohtsu Hiroshi;Chen Zhong;Hu Wei-Wei |
| 14 | Therapeutic potential of an anti-high mobility group box-1 monoclonal antibody in epilepsy | 期刊论文 | Zhao Junli;Wang Yi;Xu Cenglin;Liu Keyue;Wang Ying;Chen Liying;Wu Xiaohua;Gao Feng;Guo Yi;Zhu Junming;Wang Shuang;Nishibori Masahiro;Chen Zhong |
| 15 | Low-frequency stimulation in anterior nucleus of thalamus alleviates kainate-induced chronic epilepsy and modulates the hippocampal EEG rhythm | 期刊论文 | Wang Yi;Liang Jiao;Xu Cenglin;Wang Ying;Kuang Yifang;Xu Zhenghao;Guo Yi;Wang Shuang;Gao Feng;Chen Zhong |
| 16 | Dysfunction of thermoregulation contributes to the generation of hyperthermia-induced seizures | 期刊论文 | Feng Bo;Tang Yang-Shun;Chen Bin;Dai Yun-Jian;Xu Ceng-Lin;Xu Zheng-Hao;Zhang Xiang-Nan;Zhang Shi-Hong;Hu Wei-Wei;Chen Zhong |
| 17 | Depolarized GABAergic Signaling in Subicular Microcircuits Mediates Generalized Seizure in Temporal Lobe Epilepsy | 期刊论文 | Wang Yi;Xu Cenglin;Xu Zhenghao;Ji Caihong;Liang Jiao;Wang Ying;Chen Bin;Wu Xiaohua;Gao Feng;Wang Shuang;Guo Yi;Li Xiaoming;Luo Jianhong;Duan Shumin;Chen Zhong |
| 18 | Reorganization of anterior and posterior hippocampal networks associated with memory performance in mesial temporal lobe epilepsy | 期刊论文 | Li Hong;Ji Caihong;Zhu Lujia;Huang Peiyu;Jiang Biao;Xu Xiaojun;Sun Jianzhong;Chen Zhong;Ding Meiping;Zhang Minming;Wang Shuang |
| 19 | Low-frequency stimulation of the external globus palladium produces anti-epileptogenic and anti-ictogenic actions in rats | 期刊论文 | Cheng Hui;Kuang Yi-fang;Liu Yang;Wang Yi;Xu Zheng-hao;Gao Feng;Zhang Shi-hong;Ding Mei-ping;Chen Zhong |
| 20 | Blocking GluN2B subunits reverses the enhanced seizure susceptibility after prolonged febrile seizures with a wide therapeutic time-window | 期刊论文 | Chen Bin;Feng Bo;Tang Yangshun;You Yi;Wang Yi;Hou Weiwei;Hu Weiwei;Chen Zhong |
| 21 | Postictal generalized EEG suppression after generalized convulsive seizures: A double-edged sword | 期刊论文 | Xu Jiahui;Jin Bo;Yan Jianwei;Wang Jing;Hu Jingying;Wang Zhongjin;Chen Zhong;Ding Meiping;Chen Shuhua;Wang Shuang |
| 22 | Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures | 期刊论文 | Dai Yun-Jian;Xu Zheng-Hao;Feng Bo;Xu Ceng-Lin;Zhao Hua-Wei;Wu Deng-Chang;Hu Wei-Wei;Chen Zhong |
| 23 | Intergenerational Transmission of Enhanced Seizure Susceptibility after Febrile Seizures. | 期刊论文 | Dengchang Wu;Bo Feng;Yunjian Dai;Xiaohua Wu;Cenglin Xu;Yangshun Tang;Kang Wang;Shihong Zhang;Shuang Wang;Benyan Luo;Zhong Chen |
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