TAp73甲基化通过Dicer1调控MDS-MSC细胞衰老的机制研究

81400090
2014
H0807.骨髓增生异常综合征
赵佑山
青年科学基金项目
医师
上海交通大学
23万元
MDS;微小RNA;造血微环境;骨髓间充质干细胞;骨髓增生异常综合征/
2015-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Down-regulation of Dicer1 promotes cellular senescence and decreases the differentiation and stem cell-supporting capacities of mesenchymal stromal cells in patients with myelodysplastic syndrome 期刊论文 Zhao Youshan;Wu Dong;Fei Chengming;Guo Juan;Gu Shuncheng;Zhu Yang;Xu Feng;Zhang Zheng;Wu Lingyun;Li Xiao;Chang Chunkang
2 Iron overload promotes erythroid apoptosis through regulating HIF-1a/ROS signaling pathway in patients with myelodysplastic syndrome 期刊论文 Zheng Qing-qing;Zhao You-shan;Guo Juan;Zhao Si-da;Song Lu-xi;Fei Cheng-ming;Zhang Zheng;Li Xiao;Chang Chun-kang
3 Downregulation of MMP1 in MDS-derived mesenchymal stromal cells reduces the capacity to restrict MDS cell proliferation 期刊论文 Zhao Sida;Zhao Youshan;Guo Juan;Fei Chengming;Zheng Qingqing;Li Xiao;Chang Chunkang
4 地西他滨治疗骨髓增生异常综合征 及相关肿瘤的疗效预测因素研究 期刊论文 赵佑山;郭娟;许峰;吴东;吴凌云;宋陆茜;肖超;李晓;常春康
5 Notch-Hes pathway mediates the impaired osteogenic differentiation of bone marrow mesenchymal stromal cells from myelodysplastic syndromes patients through the down-regulation of Runx2 期刊论文 Fei Chengming;Guo Juan;Zhao Youshan;Gu Shucheng;Zhao Sida;Li Xiao;Chang Chunkang
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