基于Keap1-Nrf2-ARE信号通路的活性先导化合物的发现及作用机制研究
81373321
2013
H3405.海洋药物
韩兵男
面上项目
研究员
上海交通大学
60万元
海绵;作用机制;抗氧化物;蛋白组学;天然产物
2014-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | New Furan and Cyclopentenone Derivatives from the Sponge-Associated Fungus Hypocrea Koningii PF04 | 期刊论文 | Ding Li-Jian;Gu Bin-Bin;Jiao Wei-Hua;Yuan Wei;Li Ying-Xin;Tang Wei-Zhuo;Yu Hao-Bing;Liao Xiao-Jian;Han Bing-Nan;Li Zhi-Yong;Xu Shi-Hai;Lin Hou-Wen |
| 2 | Dysideanones A-C, Unusual Sesquiterpene Quinones from the South China Sea Sponge Dysidea avara | 期刊论文 | Jiao Wei-Hua;Xu Ting-Ting;Yu Hao-Bing;Chen Guo-Dong;Huang Xiao-Jun;Yang Fan;Li Yu-Shan;Han Bing-Nan;Liu Xiao-Yan;Lin Hou-Wen |
| 3 | N-Me-trichodermamide B isolated from Penicillium janthinellum, with antioxidant properties through Nrf2-mediated signaling pathway | 期刊论文 | Zhen Yang;Mei-lin Zhu;De-hai Li;Rong Zeng;Bing-Nan Han |
| 4 | Sesquiterpene Quinones/Hydroquinones from the Marine Sponge Spongia pertusa Esper | 期刊论文 | Li Jing;Gu Bin-Bin;Sun Fan;Xu Jian-Rong;Jiao Wei-Hua;Yu Hao-Bing;Han Bing-Nan;Yang Fan;Zhang Xi-Chun;Lin Hou-Wen |
| 5 | PPAR Modulating Polyketides from a Chinese Plakortis simplex and Clues on the Origin of Their Chemodiversity | 期刊论文 | Chianese Giuseppina;Yu Hao-Bing;Yang Fan;Sirignano Carmina;Luciano Paolo;Han Bing-Nan;Khan Shabana;Lin Hou-Wen;Taglialatela-Scafati Orazio |
| 6 | 一种生物碱类化合物及抗氧化的应用 | 专利 | 韩兵男;杨珍;曾嵘;李德海;朱美林;梁婷婷 |
| 7 | Hypocrol A, a new tyrosol derivative from a sponge-derived strain of the fungus Hypocrea koningii | 期刊论文 | Ding Li-Jian;Yuan Wei;Li Ying-Xin;Liao Xiao-Jian;Sun Huan;Peng Qi;Han Bing-Nan;Lin Hou-Wen;Li Zhi-Yong;Yang Fan;Xu Shi-Hai |
| 8 | Three new aaptamine derivatives from the South China Sea sponge Aaptos aaptos | 期刊论文 | Gan Jian-Hong;Hu Wen-Zhen;Yu Hao-Bing;Yang Fan;Cao Meng-Xue;Shi Hua-Jin;Kang Yong-Feng;Han Bing-Nan |
| 9 | Antifungal bromopyrrole alkaloids from the South China Sea sponge Agelas sp. | 期刊论文 | Zhu Yan;Wang Yan;Gu Bin-Bin;Yang Fan;Jiao Wei-Hua;Hu Gan-Hai;Yu Hao-Bing;Han Bing-Nan;Zhang Wei;Shen Yang;Lin Hou-Wen |
| 10 | Dysiherbols A-C and Dysideanone E, Cytotoxic and NF-kappa B Inhibitory Tetracyclic Meroterpenes from a Dysidea sp Marine Sponge | 期刊论文 | Jiao Wei-Hua;Shi Guo-Hua;Xu Ting-Ting;Chen Guo-Dong;Gu Bin-Bin;Wang Zhuo;Peng Shuang;Wang Shu-Ping;Li Jia;Han Bing-Nan;Zhang Wei;Lin Hou-Wen |
| 11 | 一种聚酮类化合物及其制备方法和应用 | 专利 | 韩兵男;梁婷婷;郑玲辉 |
| 12 | Trichodermamides D-F, heterocyclic dipeptides with a highly functionalized 1,2-oxazadecaline core isolated from the endophytic fungus Penicillium janthinellum HDN13-309 | 期刊论文 | Zhu Meilin;Yang Zhen;Feng Huimin;Gan Qi;Che Qian;Zhu Tianjiao;Gu Qianqun;Han Bingnan;Li Dehai |
| 13 | Oryzamides A-E, Cyclodepsipeptides from the Sponge-Derived Fungus Nigrospora oryzae PF18 | 期刊论文 | Ding Li-Jian;Yuan Wei;Liao Xiao-Jian;Han Bing-Nan;Wang Shu-Ping;Li Zhi-Yong;Xu Shi-Hai;Zhang Wei;Lin Hou-Wen |
| 14 | Bioactive sesquiterpene quinols and quinones from the marine sponge Dysidea avara | 期刊论文 | wei-hua jiao;ting-ting xu;bin-bin gu;guo-hua shi;yan zhu;fan yang;bing-nan han;shu-ping wang;yu-shan li;wei zhang;jia li;hou-wen lin |
| 15 | New hippolide derivatives with protein tyrosine phosphatase 1B inhibitory activity from the marine sponge Hippospongia lachne. | 期刊论文 | Piao Shu-Juan;Jiao Wei-Hua;Yang Fan;Yi Yang-Hua;Di Ying-Tong;Han Bing-Nan;Lin Hou-Wen |
| 16 | Reniochalistatins A-E, Cyclic Peptides from the Marine Sponge Reniochalina stalagmitis. | 期刊论文 | Zhan Kai-Xuan;Jiao Wei-Hua;Yang Fan;Li Jing;Wang Shu-Ping;Li Yu-Shan;Han Bing-Nan;Lin Hou-Wen |
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