【31170875】大肠杆菌麦芽糖结合蛋白与卡介苗协同促进Th1细胞活化机制及其抑制肿瘤生长作用研究国家自然基金项目

大肠杆菌麦芽糖结合蛋白与卡介苗协同促进Th1细胞活化机制及其抑制肿瘤生长作用研究

项目批准号： 31170875

批准年份： 2011

学科分类： C0804.自身免疫与免疫耐受

项目负责人：台桂香

资助类别：面上项目

负责人职称：教授

依托单位：吉林大学

资助金额： 60万元

关键词： BCG;抗肿瘤;Th1;Calmette-Guerin;protein;疫苗佐剂;maltose;MBP;binding;Bacillus

起止时间： 2012-01-01到2015-12-31

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序号	标题	类型	作者
1	Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21(WAF1) pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells	期刊论文	Ruiping Zhai\|Dan Shao\|Weihua Ni\|Guixiang Tai\|
2	Impact of Mucin1 knockdown on the phenotypic characteristics of the human hepatocellular carcinoma cell line SMMC-7721	期刊论文	Fang Wang\|Yingying Guo\|Weihua Ni\|Guixiang Tai\|
3	Expression of human full-length MUC1 inhibits the proliferation and migration of a B16 mouse melanoma cell line	期刊论文	Juan Wang\|Fang Wang\|Sujun Gao\|Guixiang Tai\|
4	大肠杆菌麦芽糖结合蛋白对肿瘤细胞培养上清诱导的M2型巨噬细胞的翻转作用	会议论文
5	大肠杆菌麦芽糖结合蛋白联合卡介苗体外协同诱导小鼠Th1细胞活化及机制。	会议论文
6	Escherichia coli maltose-binding protein (MBP) directly induces mouse Th1 activation through upregulating TLR2 and downregulating TLR4 expressions	期刊论文	Ruiping Zhai\|Tanxiu Chen\|Qiongshu Li\|Guixiang Tai\|
7	大肠杆菌麦芽糖结合蛋白增强MUC1多肽的抗肿瘤免疫活性研究	会议论文
8	Mucin1 mediates autocrine transforming growth factor beta signaling through activating the c-Jun N-terminal kinase/activator protein 1 pathway in human hepatocellular carcinoma cells	期刊论文	Tanxiu Chen\|Ruiping Zhai\|Weihua Ni\|Guixiang Tai\|
9	Synergistic antitumor effects of Escherichia coli maltose binding protein and Bacillus Calmette-Guerin in a mouse lung carcinoma model	期刊论文	Xiaoxia Zhao,\|Fengli Wang\|Zhuo Gao\|Guixiang Tai\|
10	Escherichia coli Maltose-Binding Protein Induces M1 Polarity of RAW264.7 Macrophage Cells via a TLR2- and TLR4-Dependent Manner	期刊论文	Ruiping Zhai\|Tanxiu Chen\|Qiongshu Li\|Guixiang Tai\|
11	Escherichia coli maltose binding protein activates mouse peritoneal macrophages and polarizes them into M1-type in vivo and in vitro	期刊论文	Zhang X\|Xie F\|Li Q\|Tai G\|
12	大肠杆菌麦芽糖结合蛋白（MBP）诱导小鼠腹腔巨噬细胞活化并向M1型分化	会议论文
13	Maltose-binding protein isolated from Escherichia coli induces Toll-like receptor 2-mediated viability in U937 cells	期刊论文	Yingying Li\|Xiaxia Sun\|Zhonghui Liu\|Guixiang Tai\|
14	Impact of mucin1 knockdown on the phenotypic characteristics of the human hepatocellular carcinoma cell line SMMC-7721.	期刊论文	Wang F\|Guo Y\|Ni W\|Tai G\|
15	Escherichia coli maltose-binding protein activates mouse peritoneal macrophages and induces M1 polarization via TLR2/4 in vivo and in vitro	期刊论文	Xu Zhang\|Fei Xie\|Qiongshu Li\|Guixiang Tai\|
16	卡介苗诱导小鼠脾脏树突状细胞分化作用研究	期刊论文	方芳\|孙霞霞\|李莹莹\|台桂香\|

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