骨髓间充质干细胞成骨功能异常在骨髓增生异常综合征发病机制中的作用

81170463
2011
H0801.造血、造血调控与造血微环境
常春康
面上项目
主任医师
上海交通大学
60万元
MDS;成骨作用;BMSC;Notch信号通路
2012-01-01到2015-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 染发次数与骨髓增生异常综合征患者部分预后因素的相关性分析 期刊论文 张耀|常春康等|
2 骨髓增生异常综合征小鼠模型研究进展 期刊论文 张耀|常春康等|
3 SDF-1/CXCR4 signal is involved in decreased expression of p57kip2 in de novo MDS patients. 期刊论文 S Gu|Zhang X|Li X|Chang C|
4 骨髓增生异常综合征细胞周期相关分子表达的初步研究 期刊论文 费成明|张曦|李晓|常春康|
5 Notch-Hes pathway mediates the impaired osteogenic differentiation of bone marrow mesenchymal stromal cells from myelodysplastic syndromes patients through the down-regulation of Runx2. 期刊论文 Fei C, Guo J, Zhao Y, Gu S, Zhao S, Li X1, Chang C|
6 Bone Marrow Mesenchymal Stem Cells in Myelodysplastic Syndromes: Cytogenetic Characterization. 期刊论文 J Guo| Q He| chunkang chang| et al|
7 Decitabine Treatment Could Ameliorate Primary Iron-Overload in Myelodysplastic Syndrome Patients. 期刊论文 Chengming, Fei|Xi, Zhang|Chao, Xiao|Xiao, Li|
8 Senescence of bone marrow mesenchymal stromal cells is accompanied by activation of p53/p21 pathway in myelodysplastic syndromes 期刊论文 常春康|
9 骨髓增生异常综合征细胞周期相关分子表达的初步研究 期刊论文 费成明|张曦|李晓|常春康|
10 铁调素的表达与调节机制研究进展 期刊论文 常春康等|
11 The evaluation of iron overload through hepcidin level and its related factors in myelodysplastic syndromes. 期刊论文 Zhang, Xi|Zhao, Jungong|Chang, Chunkang|Li, Xiao|
12 Impaired osteogenic differentiation of mesenchymal stem cells derived from bone marrow of patients with lower-risk myelodysplastic syndromes. 期刊论文 Guo, Juan|Zhang, Xi|Li, Xiao|Chang, Chunkang|
13 p53与细胞衰老关系的研究进展 期刊论文 赵思达|常春康|
14 Methylation of the p73 gene in patients with myelodysplastic syndromes: correlations with apoptosis and prognosis. 期刊论文 Guo, Juan|Gu, Shucheng|Li, Xiao|Chang, Chunkang|
15 成骨细胞在造血微环境中的作用及与部分血液系统疾病关系的研究进展 期刊论文 费成明, 常春康|
16 Down-regulation of Dicer1 promotes cellular senescence and decreases the differentiation and stem cell-supporting capacities of mesenchymal stromal cells in patients with myelodysplastic syndrome. 期刊论文 Zhang, Zheng|Wu, Lingyun|Li, Xiao|Chang, Chunkang|
17 骨髓增生异常综合征患者骨髓间充质干细胞的相关特征概述 期刊论文 韩爽|常春康|
18 Downregulation of p21 in Myelodysplastic Syndrome Is Associated With p73 Promoter Hypermethylation and Indicates Poor Prognosis. 期刊论文 Gu, Shucheng|Fei, Chengmin|Li, Xiao|Chang, Chunkang|
19 骨髓增生异常综合征患者骨髓间充质干细胞的相关特征概述 期刊论文 韩爽|常春康|
20 p57kip2 在初发MDS 患者的表达及与SDF-1/CXCR4 信号的关系 期刊论文 赵佑山|常春康等|
21 Aberration of p73 promoter methylation in de novo myelodysplastic syndrome. 期刊论文 Zhang Z|Zhang X|Li X|chunkang chang|
22 MDS患者祛铁治疗与缓解EPO抵抗的初步研究 期刊论文 张耀,肖超,顾树程,常春康|
23 Impaired osteogenic differentiation of mesenchymal stem cells derived from bone marrow of patients with lower-risk myelodysplastic syndromes 期刊论文 常春康|
24 Senescence of bone marrow mesenchymal stromal cells is accompanied by activation of p53/p21 pathway in myelodysplastic syndromes. 期刊论文 Guo J|Gu S|Li X|Chang C|
25 Notch配体Delta-like-1和Jagged-1 mRNA在骨髓增生异常综合征患者骨髓间充质干细胞中表达研究 期刊论文 赵佑山|郭娟|李晓|常春康|
26 应用流式细胞术评估多发性骨髓瘤预后的研究进展 期刊论文 郭娟,常春康,苏基滢, 张曦,李晓|
27 High expression of APAF-1 elevates erythroid apoptosis in iron overload myelodysplastic syndrome. 期刊论文 Zhang, Xi|Xiao, Chao|Chang, Chunkang|Li, Xiao|
28 High expression of APAF-1 elevates erythroid apoptosis in iron overload myelodysplastic syndrome 期刊论文 常春康|
29 骨髓增生异常综合征患者p73基因启动子区域异常甲基化的研究 期刊论文 赵佑山|常春康等|
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