BMP4绑定LncRNA协同组蛋白H3K4甲基化修饰调控鸡PGCs特化的机制
31872341
2018
C1703.家禽及其他经济动物种质资源与遗传育种学
李碧春
面上项目
教授
扬州大学
59万元
长链非编码RNA;表观遗传;原始生殖细胞;鸡;组蛋白甲基化修饰
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Spin1z induces the male pathway in the chicken by down-regulating Tcf4 | 期刊论文 | Jingyi Jiang;Chen Zhang;Xia Yuan;Jiancheng Li;Ming Zhang;Xiang Shi;Kai Jin;Yani Zhang;Qisheng Zuo;Guohong Chen;Bichun Li |
| 2 | The expression of Lin28B was co-regulated by H3K4me2 and Wnt5a/β-catenin/TCF7L2 | 期刊论文 | Ya-ni ZHANG;Cai HU;Ying-jie WANG;Qi-sheng ZUO;Bi-chun LI |
| 3 | DHCR24 (24-Dehydrocholesterol Reductase) Associated in Modulating Steroid Biosynthesis Pathway Regulates the Differentiation of Chicken Embryonic Stem Cells into Male Germ Cells | 期刊论文 | Kai Jin;Yiling Wang;Changhua Sun;Qisheng Zuo;Yani Zhang;Guohong Chen;Bichun Li |
| 4 | 鸡原始生殖细胞中lncRNA-CEPT8编码小肽能力的研究 | 期刊论文 | 余昕健;靳锴;金晶;左其生;赵瑞丰;李碧春 |
| 5 | 鸡Rbbp5基因的生物信息学分析及过表达载体构建 | 期刊论文 | 王生存;张晨;左其生;邹艺琛;赵娟娟;张亚妮;李碧春 |
| 6 | 鸡体细胞诱导重编程早期的糖代谢变化研究 | 期刊论文 | 袁霞;王佳琪;王美瑰;孙国兴;姜景译;石祥;张明;丁颖;左其生;张亚妮;李碧春 |
| 7 | Narrow H3K4me2 is required for chicken PGC formation | 期刊论文 | Chen Zhang;Qisheng Zuo;Man Wang;Hao Chen;Nana He;Jing Jin;Tingting Li;Jingyi Jiang;Xia Yuan;Jiancheng Li;Xiang Shi;Ming Zhang;Hao Bai;Yang Zhang;Qi Xu;Hengmi Cui;Guobin Chang;Jiuzhou Song;Hongyan Sun;Yani Zhang;Guohong Chen;Bichun Li |
| 8 | Analysis of lncRNA Expression Profile during the Formation of Male Germ Cells in Chickens | 期刊论文 | Wen Gao;Chen Zhang;Kai Jin;Yani Zhang;Qisheng Zuo;Bichun Li |
| 9 | 鸡Wnt5a基因慢病毒干扰载体的构建及其稳定表达的胚胎干细胞系筛选 | 期刊论文 | 周静;金晶;何娜娜;张晨;王曼;左其生;张亚妮;李碧春 |
| 10 | Comparison of the effects of three cryoprotectants on the cryopreservation of mouse subcutaneous tissue under different conditions | 期刊论文 | Shengcun Wang;Xia Yuan;Jing Zhou;Jing Jin;Qisheng Zuo;Bichun Li |
| 11 | 鸡bmp4过表达和敲除载体构建及活性验证 | 期刊论文 | 李婷婷;孙长花;周舒简;金晶;张亚妮;左其生 |
| 12 | Study on the Function and Mechanism of Lin28B in the Formation of Chicken Primordial Germ Cells | 期刊论文 | Zuo Qisheng;Zhou Jing;Wang Man;Zhang Yani;Chen Guohong;Li Bichun |
| 13 | 鸡Ash2l基因携带Flag标签的真核融合表达载体构建及表达分析 | 期刊论文 | 张晨;左其生;邹艺琛;赵娟娟;张亚妮;李碧春 |
| 14 | 鸡 lncRNA-CEPT8 启动子验证及活性核心区域筛选 | 期刊论文 | 金晶;余昕健;靳锴;李婷婷;张晨;左其生;李碧春 |
| 15 | H3K4me2 Promotes the Activation of lncCPSET1 by Jun in the Chicken PGC Formation | 期刊论文 | Chen Zhang;Qisheng Zuo;Xiaomin Gao;Cai Hu;Shujian Zhou;Chen Chen;Yichen Zou;Juanjuan Zhao;Yani Zhang;Bichun Li |
| 16 | 一种通过羽色结合分子遗传标记鉴别PGC移植后代鸡的鉴定方法 | 专利 | 左其生;金晶;李碧春;赵瑞丰;李婷婷;袁霞;靳锴 |
| 17 | 一种lncRNA通过编码小肽促进PGCs形成的验证方法 | 专利 | 左其生;姜景译;李碧春;金晶;袁霞;张晨 |
| 18 | P53 and H3K4me2 activate N6‐methylated LncPGCAT‐1 to regulate primordial germ cell formation via MAPK signaling | 期刊论文 | Qisheng Zuo;Jing Jin;Kai Jin;Jing Zhou;Changhua Sun;Jiuzhou Song;Guohong Chen;Yani Zhang;Bichun Li |
| 19 | 一种研究鸡PGCs中lncRNA和组蛋白甲基化酶共调控靶基因的方法 | 专利 | 李碧春;张晨;左其生;张亚妮;孙红艳 |
| 20 | 一种研究组蛋白H3K4me2酶/转录因子复合体调控靶基因转录的方法 | 专利 | 李碧春;张晨;左其生;张亚妮;孙红艳 |
| 21 | 一种探究胚胎期肌肉细胞形成时间的方法 | 专利 | 靳锴;周静;牛英杰;左其生;孙红艳;张亚妮;李碧春 |
| 22 | Tle4z1 Facilitate the Male Sexual Differentiation of Chicken Embryos | 期刊论文 | Chen Chen;Shujian Zhou;Ziyi Lian;Jingyi Jiang;Xiaomin Gao;Cai Hu;Qisheng Zuo;Yani Zhang;Guohong Chen;Kai Jin;Bichun Li |
| 23 | Epigenetic modification cooperates with Zeb1 transcription factor to regulate Bmp4 to promote chicken PGCs formation | 期刊论文 | Shujian Zhou;Tingting Li;Ming Zhang;Chen Chen;Xiaomin Gao;Chen Zhang;Cai Hu;Qishenng Zuo;Guohong Chen;Bichun Li |
| 24 | Long Noncoding RNA LncPGCR Mediated by TCF7L2 Regulates Primordial Germ Cell Formation in Chickens | 期刊论文 | Jingyi Jiang;Chen Chen;Shaoze Cheng;Xia Yuan;Jing Jin;Chen Zhang;Xiaolin Sun;Jiuzhou Song;Qisheng Zuo;Yani Zhang;Guohong Chen;Bichun Li |
| 25 | STAT1和组蛋白乙酰化修饰调控鸡lncRNA-BMP4转录研究 | 期刊论文 | 高晓敏;周舒简;陈晨;金晶;胡菜;张晨;左其生;张亚妮;陈国宏;李碧春 |
| 26 | OCT4, SOX2 and NANOG co-regulate glycolysis and participate in somatic induced reprogramming | 期刊论文 | Ying Ding;Xia Yuan;Yichen Zou;Jiachen Gao;Xianshuai Xu;Hongyan Sun;Qisheng Zuo;Yani Zhang;Bichun Li |
| 27 | Glycolysis Combined with Core Pluripotency Factors to Promote the Formation of Chicken Induced Pluripotent Stem Cells | 期刊论文 | Xia Yuan;Chen Zhang;Ruifeng Zhao;Jingyi Jiang;Xiang Shi;Ming Zhang;Hongyan Sun;Qisheng Zuo;Yani Zhang;Jiuzhou Song;Guohong Chen;Bichun Li |
| 28 | BMP4 activates the Wnt-Lin28A-Blimp1-Wnt pathway to promote primordial germ cells formation via altering H3K4me2 | 期刊论文 | Qisheng Zuo;Kai Jin;Man Wang;Yani Zhang;Guohong Chen;Bichun Li |
| 29 | Dual regulatory actions of LncBMP4 on BMP4 promote chicken primordial germ cell formation | 期刊论文 | Zuo Qisheng;Jing Jin;Zhou Jing;Zhang Yani;Wei Wanhong;Chen Guohong;Li Bichun |
| 30 | 一种利用CRISPR-Cas9靶向敲除鸡Bmp4基因的方法 | 专利 | 李碧春;高雯;左其生;张晨;袁霞;姜景译;丁颖;张亚妮;孙红艳 |
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