辅受体CD8增强TCR抗原识别的力学-化学耦合调控的分子机制研究
31971237
2019
C1001.生物力学与生物流变学
陈伟
面上项目
教授
浙江大学
58万元
TCR抗原识别;力学-化学耦合;反应动力学;受体-配体相互作用;单分子力学
2020-01-01到2023-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | NKG2D discriminates diverse ligands through selectively mechano‐regulated ligand conformational changes | 期刊论文 | Juan Fan;Jiawei Shi;Yong Zhang;Junwei Liu;Chenqi An;Huaying Zhu;Peng Wu;Wei Hu;Rui Qin;Danmei Yao;Xin Shou;Yibing Xu;Zhou Tong;Xue Wen;Jianpo Xu;Jin Zhang;Weijia Fang;Jizhong Lou;Weiwei Yin;Wei Chen |
| 2 | T cell proliferation requires ribosomal maturation in nucleolar condensates dependent on DCAF13 | 期刊论文 | Lina Zhou;Shuai Wang;Wei Hu;Xiaoqian Liu;Lingdong Xu;Bolu Tong;Tongtong Zhang;Zhonghui Xue;Yixin Guo;Jing Zhao;Linrong Lu;Hengyu Fan;Wenbin Qian;Jian Chen;Wei Chen;Lie Wang |
| 3 | Physical-chemical regulation of membrane receptors dynamics in viral invasion and immune defense | 期刊论文 | Rui Qin;Chenyi An;Wei Chen |
| 4 | A loosened gating mechanism of RIG-I leads to autoimmune disorders | 期刊论文 | Yixuan Lei;Panyu Fei;Bin Song;Wenjia Shi;Cheng Luo;Dahai Luo;Dan Li;Wei Chen;Jie Zheng |
| 5 | Self-programmed dynamics of T cell receptor condensation | 期刊论文 | Hui Chen;Xinyi Xu;Wei Hu;Songfang Wu;Jianhui Xiao;Peng Wu;Xiaowen Wang;Xuling Han;Yanruo Zhang;Yong Zhang;Ning Jiang;Wanli Liu;Changjie Lou;Wei Chen;Chenqi Xu;Jizhong Lou |
| 6 | Ultra-stable Biomembrane Force Probe for Accurately Determining Slow Dissociation Kinetics of PD-1 Blockade Antibodies on Single Living Cells | 期刊论文 | Chenyi An;Wei Hu;Jie Gao;Bing-Feng Ju;Peyman Obeidy;Yunduo Charles Zhao;Xiaoxuan Tu;Weijia Fang;Lining Arnold Ju;Wei Chen |
| 7 | Mechanical activation of spike fosters SARS-CoV-2 viral infection | 期刊论文 | Wei Hu;Yong Zhang;Panyu Fei;Tongtong Zhang;Danmei Yao;Yufei Gao;Jia Liu;Hui Chen;Qiao Lu;Tenny Mudianto;Xinrui Zhang;Chuxuan Xiao;Yang Ye;Qiming Sun;Jing Zhang;Qi Xie;Pei-Hui Wang;Jun Wang;Zhenhai Li;Jizhong Lou;Wei Chen |
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