组蛋白去甲基化酶PHF8调控线粒体稳态和细胞能量代谢的功能和分子机制研究
31871319
2018
C0602.基因表达及非编码序列调控
刘文
面上项目
教授
厦门大学
60万元
线粒体稳态;肿瘤发生;细胞能量代谢;人类;表观遗传调控
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Long non-coding RNA LINC00680 functions as a ceRNA to promote esophageal squamous cell carcinoma progression through the miR-423-5p/PAK6 axis | 期刊论文 | Songtao Xue;Bin Zheng;Shiqiang Cao;Jiancheng Ding;Guosheng Hu;Wen Liu;Chun Chen |
| 2 | The dual function of KDM5C in both gene transcriptional activation and repression promotes breast cancer cell growth and tumorigenesis | 期刊论文 | Hai-feng Shen;Wen-juan Zhang;Ying Huang;Yao-hui He;Guo-sheng Hu;Lei Wang;Bing-ling Peng;Jia Yi;Ting-ting Li;Rui Rong;Xiao-yan Chen;Jun-yi Liu;Wen-juan Li;Kenny Ohgi;Shao-Wei Li;Michael G. Rosenfeld;Wen Liu |
| 3 | A hypermethylation strategy utilized by enhancer-bound CARM1 to promote estrogen receptor α-dependent transcriptional activation and breast carcinogenesis | 期刊论文 | Bing-ling Peng;Wen-juan Li;Jian-cheng Ding;Yao-hui He;Ting Ran;Bing-lan Xie;Zi-rui Wang;Hai-feng Shen;Rong-quan Xiao;Wei-wei Gao;Tian-yi Ye;Xiang Gao;Wen Liu |
| 4 | 一种四氢咔唑-1-甲酰胺类衍生物及其制备方法和应用 | 专利 | 刘文;吴振;吴晓男;李博群;李佳媛;何琪 |
| 5 | Estrogen-induced circRNA, circPGR, functions as a ceRNA to promote estrogen receptor-positive breast cancer cell growth by regulating cell cycle-related genes | 期刊论文 | Lei Wang;Jia Yi;Ling-yun Lu;Yue-ying Zhang;Lan Wang;Guo-sheng Hu;Yi-chen Liu;Jian-cheng Ding;Hai-feng Shen;Fang-qing Zhao;Hai-hua Huang;Wen Liu |
| 6 | Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting. | 期刊论文 | Wei Liu;Lei Xie;Yaohui He;Zhiyong Wu;Luxin Liu;Xuefeng Bai;Danxia Deng;Xiue Xu;Liandi Liao;Wan Lin;Jinghua Heng;Xin Xu;Liu Peng;Qingfeng Huang;Chengyu Li;Zhida Zhang;Wei Wang;Guorui Zhang;Xiang Gao;Shaohong Wang;Chunquan Li;Liyan Xu;Wen Liu;Enmin Li |
| 7 | BRD4 inhibition boosts the therapeutic effects of epidermal growth factor receptor-targeted chimeric antigen receptor T cells in glioblastoma | 期刊论文 | Lin Xia;Jun-yi Liu;Zao-zao Zheng;Yu-jie Chen;Jian-cheng Ding;Ya-hong Hu;Guo-sheng Hu;Ning-shao Xia;Wen Liu |
| 8 | LncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling | 期刊论文 | Xiaoting Lin;Shiwen Zhuang;Xue Chen;Jun Du;Longhua Zhong;Jiancheng Ding;Lei Wang;Jia Yi;Guosheng Hu;Guohui Tang;Xi Luo;Wen Liu;Feng Ye |
| 9 | LncRNA LUCRC regulates colorectal cancer cell growth and tumorigenesis by targeting endoplasmic reticulum stress response | 期刊论文 | Guo-Hui Tang;Xue Chen;Jian-Cheng Ding;Jun Du;Xiao-Ting Lin;Lu Xia;Jia-Bian Lian;Feng Ye;Xiu-Sheng He;Wen Liu |
| 10 | Targeting triple-negative breast cancer with combination therapy of epidermal growth factor receptor-targeted chimeric antigen receptor T cell and CDK7 inhibitor | 期刊论文 | Lin Xia;Zao-zao Zheng;Jun-yi Liu;Yu-jie Chen;Jian-cheng Ding;Guo-sheng Hu;Ya-hong Hu;Su-ling Liu;Wen-xin Luo;Ning-shao Xia;Wen Liu |
| 11 | CPPA: A Web Tool for Exploring Proteomic and Phosphoproteomic Data in Cancer | 期刊论文 | Guo-sheng Hu;Zao-zao Zheng;Yao-hui He;Du-chuang Wang;Wen Liu |
| 12 | Super-enhancer-controlled positive feedback loop BRD4/ERα–RET–ERα promotes ERα-positive breast cancer | 期刊论文 | Zao-zao Zheng;Lin Xia;Guo-sheng Hu;Jun-yi Liu;Ya-hong Hu;Yu-jie Chen;Jia-yin Peng;Wen-juan Zhang;Wen Liu |
| 13 | In silico discovery of JMJD6 inhibitors for cancer treatment | 期刊论文 | Ting Ran;Rongquan Xiao;Qixuan Huang;Haoliang Yuan;Tao Lu;Wen Liu |
| 14 | EGFR-targeted CAR-T cells are potent and specific in suppressing triple-negative breast cancer both in vitro and in vivo | 期刊论文 | Lin Xia;Zao-zao Zheng;Jun-yi Liu;Yu-jie Chen;Jian-cheng Ding;Ning-shao Xia;Wen-xin Luo;Wen Liu |
| 15 | A specific JMJD6 inhibitor potently suppresses multiple types of cancers both in vitro and in vivo | 期刊论文 | Rong-quan Xiao;Ting Ran;Qi-xuan Huang;Guo-sheng Hu;Da-meng Fan;Jia Yi;Wen Liu |
| 16 | Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth | 期刊论文 | Wen-juan Li;Yao-hui He;Jing-jing Yang;Guo-sheng Hu;Yi-an Lin;Ting Ran;Bing-ling Peng;Bing-lan Xie;Ming-feng Huang;Xiang Gao;Hai-hua Huang;Helen He Zhu;Feng Ye;Wen Liu |
| 17 | Virtual Screening with a Structure-Based Pharmacophore Model to Identify Small-Molecule Inhibitors of CARM1 | 期刊论文 | Ting Ran;Wenjuan Li;Bingling Peng;Binglan Xie;Tao Lu;Shuai Lu;Wen Liu |
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