人朊病毒蛋白G127V多态性保护作用的结构基础

31670741
2016
C0501.结构生物学
林东海
面上项目
教授
厦门大学
65万元
多态性;结构基础;人朊病毒蛋白;核磁共振;G127V
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Distinct effects of mutations on biophysical properties of human prion protein monomers and oligomers 期刊论文 Yuanhui Yu;Ziyao Yu;Zhen Zheng;Huilin Wang;Xueji Wu;Chenyun Guo;Donghai Lin
2 Structural Basisfor the Completely Diseases-Resistant Mutant G127V of Human Pprion Protein 会议论文 Zhen Zheng;Meilan Zhang;Yongheng Wang;Liubin Feng;Hongwei Yao;Chenyun Guo;Donghai Lin
3 Structural Basis for the complete resistant of the human prion protein mutant G127V to prion disease 会议论文 Zhen Zheng;Meilan Zhang;Yongheng Wang;Liubin Feng;Hongwei Yao;Chenyun Guo;Donghai Lin
4 Critical evaluation of bioinformatics tools for the prediction of protein crystallization propensity 期刊论文 Huilin Wang;Liubin Feng;Geoffrey I. Webb;Lukasz Kurgan;Jiangning Song;Donghai Lin
5 Biophysical characterization and ligand-binding properties of the elongation factor Tu from Mycobacterium tuberculosis 期刊论文 Juanjuan Yang;Jing Hong;Ling Luo;Ke Liu;Chun Meng;Zhi liang Ji;Donghai Lin
6 Expression, purification and characterization of the full-length SmpB protein from Mycobacterium tuberculosis 期刊论文 Juanjuan Yang;Yindi Liu;Shuli Xu;Haiying Lin;Chun Meng;Donghai Lin
7 Backbone and side-chain resonance assignments for the tmRNA-binding protein, SmpB, from Mycobacterium tuberculosis 期刊论文 Juanjuan Yang;Yindi Liu;Zhao Liu;Chun Meng;Donghai Lin
8 Structural basis for the protective effect of the human prion protein carrying the dominant-negative G127V polymorphism 会议论文 Zhen Zheng;Meilan Zhang;Yongheng Wang;Liubin Feng;Hongwei Yao;Chenyun Guo;Donghai Lin
9 Biophysical characterization of oligomerization and fibrillization of the G131V pathogenic mutant of human prion protein 期刊论文 Meilan Zhang;Haoran Zhang;Hongwei Yao;Chenyun Guo;Donghai Lin
10 Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease 期刊论文 Zhen Zheng;Meilan Zhang;Yongheng Wang;Rongsheng Ma;Chenyun Guo;Liubin Feng;Jihui Wu;Hongwei Yao;Donghai Lin
11 Anti-leprosy drug Clofazimine binds to human Raf1 kinase inhibitory protein and enhances ERK phosphorylation 期刊论文 Chenyun Guo;Ting Chang;Tao Sun;Zhihua Wu;Yazhuang Dai;Hongwei Yao;Donghai Lin
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