Cdk5 磷酸化Bag3 及其在神经元突触功能和凋亡中的作用与机制研究
31571055
2015
C0901.分子与细胞神经生物学
张杰
面上项目
教授
厦门大学
64万元
阿尔茨海默病;神经元凋亡;磷酸化;细胞周期蛋白激酶Cdk5;Bag3
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation. | 期刊论文 | Leng Lige;Zhuang Kai;Liu Zeyue;Huang Changquan;Gao Yuehong;Chen Guimiao;Lin Hui;Hu Yu;Wu Di;Shi Meng;Xie Wenting;Sun Hao;Shao Zhicheng;Li Huifang;Zhang Kunkun;Mo Wei;Huang Timothy Y;Xue Maoqiang;Yuan Zengqiang;Zhang Xia;Bu Guojun;Xu Huaxi;Xu Qi;Zhang Jie |
| 2 | Cyclin-dependent kinase 5-mediated phosphorylation of chloride intracellular channel 4 promotes oxidative stress-induced neuronal death | 期刊论文 | Guo Dong;Xie Wenting;Xiong Pan;Li Huifang;Wang Siqi;Chen Guimiao;Gao Yuehong;Zhou Jiechao;Zhang Ye;Bu Guojun;Xue Maoqiang;Zhang Jie |
| 3 | Cyclin-Dependent Kinase 5-Dependent BAG3 Degradation Modulates Synaptic Protein Turnover | 期刊论文 | Zhou Jie Chao;Chow Hei-Man;Yan Liu;Di Wu;Meng Shi;Jieyin Li;Lei Wen;Yuehong Gao;Guimiao Chen;Kai Zhuang;Hui Lin;Guanyun Zhang;Wenting Xie;Huifang Li;Lige Leng;Mengdan Wang;Naizhen Zheng;Hao Sun;Yingjun Zhao;Yunwu Zhang;Maoqiang Xue;Timothy Y. Huang;Guojun Bu;Huaxi Xu;Zengqiang Yuan;Karl Herrup;Jie Zhang |
| 4 | CDK5-mediated phosphorylation and stabilization of TPX2 promotes hepatocellular tumorigenesis | 期刊论文 | Wang Fuqiang;Zhao Wenxing;Gao Yuehong;Zhou Jiechao;Li Huifang;Zhang Guanyun;Guo Dong;Xie Chengrong;Li Jie;Yin Zhenyu;Zhang Jie |
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