内部串级修饰功能集合型树状大分子的构建及其应用于抗癌药物输送
21875211
2018
B0507.医用材料化学
周珠贤
面上项目
副教授
浙江大学
65万元
药物控制释放;抗癌纳米药物;多功能纳米载体;药物传递;可降解高分子
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Active Transportation of Liposome Enhances Tumor Accumulation, Penetration, and Therapeutic Efficacy | 期刊论文 | Wang Guowei;Wu Bihan;Li Qunying;Chen Siqin;Jin Xiaoqin;Liu Yajing;Zhou Zhuxian;Shen Youqing;Huang Pintong |
| 2 | CelluMOFs: Green, Facile, and Flexible Metal-Organic Frameworks for Versatile Applications | 期刊论文 | Zhang Bo;Chen Hongwen;Hu Qiuhui;Jiang Liming;Shen Youqing;Zhao Dan;Zhou Zhuxian |
| 3 | Enzyme-Triggered Transcytosis of Dendrimer-Drug Conjugate for Deep Penetration into Pancreatic Tumors | 期刊论文 | Wang Guowei;Zhou Zhuxian;Zhao Zhihao;Li Qunying;Wu Yulian;Yan Sheng;Shen Youqing;Huang Pintong |
| 4 | Assemblies of indocyanine green and chemotherapeutic drug to cure established tumors by synergistic chemo-photo therapy | 期刊论文 | Hu Shiqi;Dong Chengyuan;Wang Jinqiang;Liu Kexin;Zhou Quan;Xiang Jiajia;Zhou Zhuxian;Liu Fusheng;Shen Youqing |
| 5 | Self-Assembly of Oxidation-Responsive Polyethylene Glycol-Paclitaxel Prodrug for Cancer Chemotherapy | 期刊论文 | Dong Chengyuan;Zhou Quan;Xiang Jiajia;Liu Fusheng;Zhou Zhuxian;Shen Youqing |
| 6 | 一种羟基氯喹两亲性聚合物药物前体、制备方法及其应用 | 专利 | 刘祥瑞;王惠芳;白皓宇;王砾莹;唐建斌;周珠贤;申有青 |
| 7 | Unraveling Plasma Protein Corona by Ultrasonic Cavitation Augments Active‐Transporting of Liposome in Solid Tumor | 期刊论文 | Guowei Wang;Yifan Jiang;Junjun Xu;Jiaxin Shen;Tao Lin;Jifan Chen;Weidong Fei;Yating Qin;Zhuxian Zhou;Youqing Shen;Pintong Huang |
| 8 | Biocompatible Cyclodextrin-Based Metal-Organic Frameworks for Long-Term Sustained Release of Fragrances | 期刊论文 | Zhang Bo;Huang Jianxiang;Liu Kexin;Zhou Zhuxian;Jiang Liming;Shen Youqing;Zhao Dan |
| 9 | Tuning the Brightness and Photostability of Organic Dots for Multivalent Targeted Cancer Imaging and Surgery | 期刊论文 | Hailin Cong;Kaiqi Wang;Zhuha Zhou;Jiajia Yang;Ying Piao;Bing Yu;Youqing Shen;Zhuxian Zhou |
| 10 | Molecularly Precise, Bright, Photostable, and Biocompatible Cyanine Nanodots as Alternatives to Quantum Dots for Biomedical Applications | 期刊论文 | Jiajia Yang;Kaiqi Wang;Yihuan Zheng;Ying Piao;Jinqiang Wang;Jianbin Tang;Youqing Shen;Zhuxian Zhou |
| 11 | Histone Deacetylase-Triggered Self-Immolative Peptide-Cytotoxins for Cancer-Selective Drug Delivery | 期刊论文 | Bai Haoyu;Wang Huifang;Zhou Zhuha;Piao Ying;Liu Xiangrui;Tang Jianbin;Shen Xian;Shen Youqing;Zhou Zhuxian |
| 12 | A breathing A4 paper by in situ growth of green metal–organic frameworks for air freshening and cleaning | 期刊论文 | Bo Zhang;Hongwen Chen;Liming Jiang;Youqing Shen;Dan Zhao;Zhuxian Zhou |
| 13 | Glutathione-Specific and Intracellularly Labile Polymeric Nanocarrier for Efficient and Safe Cancer Gene Delivery | 期刊论文 | Wang Guowei;Zhu Dingcheng;Zhou Zhuxian;Piao Ying;Tang Jianbin;Shen Youqing |
| 14 | 一种两亲性共聚物药物前体、制备方法以及包载钙泊三醇的纳米颗粒 | 专利 | 刘祥瑞;王砾莹;顾苏芳;唐建斌;周珠贤;申有青 |
| 15 | 一种γ-环糊精金属有机框架@纤维素纤维复合材料的制备方法及其产品和应用 | 专利 | 周珠贤;申有青;张波 |
| 16 | Molecular Level Precision and High Molecular Weight Peptide Dendrimers for Drug-Specific Delivery | 期刊论文 | Xinhao Fang;Kai Gao;Jianxiang Huang;Kexin Liu;Linying Chen;Ying Piao;Xiangrui Liu;Jianbin Tang;Youqing Shen;Zhuxian Zhou |
| 17 | Tuning the Release Rate of Volatile Molecules by Pore Surface Engineering in Metal-Organic Frameworks | 期刊论文 | Chen Hongwen;Chen Huaqiang;Zhang Bo;Jiang Liming;Shen Youqing;Fu Engang;Zhao Dan;Zhou Zhuxian |
| 18 | Ultrasonic Cavitation-Assisted and Acid-Activated Transcytosis of Liposomes for Universal Active Tumor Penetration | 期刊论文 | Wang Guowei;Zhang Chao;Jiang Yifan;Song Yue;Chen Jifan;Sun Yu;Li Qunying;Zhou Zhuxian;Shen Youqing;Huang Pintong |
| 19 | Tumor-Specific Fluorescence Activation of Rhodamine Isothiocyanate Derivatives | 期刊论文 | Hu Shiqi;Jiang Haiping;Zhu Jianqiang;Wang Jinqiang;Wang Shunhao;Tang Jianbin;Zhou Zhuxian;Liu Sijin;Shen Youqing |
| 20 | 抗肿瘤纳米药物递送系统的研究现状与展望 | 期刊论文 | 周珠贤;申有青;赵宇亮 |
| 21 | Screening of Zwitterionic Liposomes with Red Blood Cell-Hitchhiking and Tumor Cell-Active Transporting Capability for Efficient Tumor Entrance | 期刊论文 | Zhao Zhihao;Feng Yupu;Xiang Jiajia;Liu Jing;Piao Ying;Shao Shiqun;Tang Jianbin;Zhou Zhuxian;Shen Youqing |
| 22 | Acidity-Responsive Shell-Sheddable Camptothecin-Based Nanofibers for Carrier-Free Cancer Drug Delivery | 期刊论文 | Zhou Zhuha;Piao Ying;Hao Lingqiao;Wang Guanyu;Zhou Zhuxian;Shen Youqing |
| 23 | Linear-Dendritic Polymer-Platinum Complexes Forming Well-Defined Nanocapsules for Acid-Responsive Drug Delivery | 期刊论文 | Kexin Liu;Jiajia Xiang;Guowei Wang;Hongxia Xu;Ying Piao;Xiangrui Liu;Jianbin Tang;Youqing Shen;Zhuxian Zhou |
| 24 | Drug-Binding Albumins Forming Stabilized Nanoparticles for Efficient Anticancer Therapy | 期刊论文 | Huang Jianxiang;Wu Bihan;Zhou Zhuxian;Hu Shiqi;Xu Hongxia;Piao Ying;Zheng Hao;Tang Jianbin;Liu Xiangrui;Shen Youqing |
| 25 | 聚乙二醇-树枝状聚赖氨酸/酸酐-顺铂复合物及其制备方法和应用 | 专利 | 周珠贤;刘珂鑫;相佳佳;唐建斌;刘祥瑞;申有青 |
| 26 | 一种荧光聚赖氨酸树枝状大分子、其制备方法和应用 | 专利 | 周珠贤;王楷淇;杨佳佳;申有青 |
| 27 | The Tumor EPR Effect for Cancer Drug Delivery: Current Status, Limitations, and Alternatives | 期刊论文 | Rui Sun;Jiajia Xiang;Quan Zhou;Ying Piao;Jianbin Tang;Shiqun Shao;Zhuxian Zhou;You Han Bae;Youqing Shen |
| 28 | 高分子载体设计与肿瘤靶向递药机制的研究 | 奖励 | 申有青;唐建斌;周珠贤;邵世群;周泉 |
| 29 | 触发式自释放喜树碱聚合物前药的合成与释放调控 | 期刊论文 | 白皓宇;周珠贤;申有青 |
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