IL-36促进CD8+T细胞分泌IL-9在肿瘤免疫中的作用及机制
31770985
2017
C0805.肿瘤免疫微环境
赵鑫
面上项目
副教授
苏州大学
55万元
肿瘤微环境;正向免疫调节;肿瘤免疫;细胞因子
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Lentivirus-mediated RNA interference targeting programmed death receptor ligand 1 increases the immunologic anti-tumor effect of dendritic cell vaccination against pancreatic cancer in SCID-hu mice | 期刊论文 | Wang Jin;Sun Mingbing;Zhu Xinguo;Zhao Hua;Mao Deli;Zhang Zhe;Zhao Xin |
| 2 | 稳定过表达IL-9的小鼠CT-26肿瘤细胞株及BALB/C小鼠皮下移植瘤模型的建立 | 期刊论文 | 王进;董晓强;赵鑫;朱新国;赵华;张江磊 |
| 3 | IL-36 beta Promotes CD8( ) T Cell Activation and Antitumor Immune Responses by Activating mTORC1 | 期刊论文 | Zhao Xin;Chen Xiaojuan;Shen Xinghua;Tang Peijun;Chen Chen;Zhu Qitai;Li Muyao;Xia Rui;Yang Xi;Feng Chao;Zhu Xinguo;Zhu Yibei;Sun Zhongwen;Zhang Xueguang;Lu Binfeng;Wang Xuefeng |
| 4 | IL-9 Exerts Antitumor Effects in Colon Cancer and Transforms the Tumor Microenvironment In Vivo | 期刊论文 | Wang Jin;Sun Mingbing;Zhao Hua;Huang Yang;Li Dongbao;Mao Deli;Zhang Zhe;Zhu Xinguo;Dong Xiaoqiang;Zhao Xin |
| 5 | IL-36β promotes anti-tumor effects in CD8+ T cells by downregulating micro-RNA let-7c-5p | 期刊论文 | Li Dongbao;Huang Yang;Yu Zhuwen;Zhang Jianglei;Hu Chenrui;Bai Yanjin;Wang Jin;Zhang Zhe;Ouyang Jun;Zhou Jin;Zhao Xin |
| 6 | Huaier increases the antitumor effect of gemcitabine on pancreatic cancer in vitro and in vivo | 期刊论文 | Chen Tao;Li Dongbao;Feng Chao;Zhang Zixiang;Zhu Dongming;Li Dechun;Zhao Xin |
| 7 | Long Noncoding RNA GM16343 Promotes IL-36 beta to Regulate Tumor Microenvironment by CD8( )T cells | 期刊论文 | Mao Deli;Hu Chenrui;Zhang Jianglei;Feng Chao;Zhang Zhe;Wang Jin;Man Zhongsong;Zhu Zhongwei;Wang Yunliang;Zhao Hua;Zhu Xinguo;Ouyang Jun;Dong Xiaoqiang;Zhao Xin |
| 8 | MicroRNA miR-29a Inhibits Colon Cancer Progression by Downregulating B7-H3 Expression: Potential Molecular Targets for Colon Cancer Therapy | 期刊论文 | Wang Jin;Chen Xiaojuan;Xie Chen;Sun Mingbing;Hu Chenrui;Zhang Zhe;Luan Lipeng;Zhou Jin;Zhou Jian;Zhu Xinguo;Ouyang Jun;Dong Xiaoqiang;Li Dechun;Zhang Jianglei;Zhao Xin |
| 9 | IL-9在结肠癌组织中的表达及其临床意义 | 期刊论文 | 王进;董晓强;朱新国;赵华;毛德利;赵鑫 |
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