肿瘤靶向多肽-药物偶联物的新型构建策略研究
81673283
2016
H3401.合成药物化学
张邦治
面上项目
教授
兰州大学
54万元
多肽-药物偶联物;肿瘤靶向;长效;成药性评价;阴离子穿膜肽
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Potent effects of amino acid scanned antimicrobial peptide Feleucin-K3 analogs against both multidrug-resistant strains and biofilms of Pseudomonas aeruginosa | 期刊论文 | Xie Junqiu;Li Yao;Li Jing;Yan Zhibin;Wang Dan;Guo Xiaomin;Zhang Jianfeng;Zhang Bangzhi;Mou Lingyun;Yang Wenle;Jiang Xianxing |
| 2 | Peptide DR8 suppresses epithelial-to-mesenchymal transition via the TGF-beta/MAPK signaling pathway in renal fibrosis | 期刊论文 | Deng Bochuan;Yang Wenle;Wang Dan;Cheng Lu;Bu Lili;Rao Jing;Zhang Jianfeng;Xie Junqiu;Zhang Bangzhi |
| 3 | 多肽药物的规模化和机械化制备技术创新及应用 | 奖励 | 王锐;崔学云;杨顶建;常民;方泉;胡晓愚;杨平;彭雅丽;倪京满;姜月霞;张邦治 |
| 4 | The antimicrobial peptide YD attenuates inflammation via miR-155 targeting CASP12 during liver fibrosis | 期刊论文 | Zhibin Yan;Dan Wang;Chunmei An;Hongjiao Xu;Qian Zhao;Ying Shi;Nazi Song;Bochuan Deng;Xiaomin Guo;Jing Rao;Lu Cheng;Bangzhi Zhang;Lingyun Mou;Wenle Yang;Xianxing Jiang;Junqiu Xie |
| 5 | p53 as a double-edged sword in the progression of non-alcoholic fatty liver disease | 期刊论文 | Yan Zhibin;Miao Xiaokang;Zhang Bangzhi;Xie Junqiu |
| 6 | Regio- and stereoselective ring-opening reaction of spiro-epoxyoxindoles with ammonia under catalyst-free conditions | 期刊论文 | Zhang Bangzhi;Li Yiping;Bao Guangjun;Zhu Gongming;Li Jing;Wang Juanli;Zhang Bao;Sun Wangsheng;Hong Liang;Wang Rui |
| 7 | 抗氧化多肽DR8在制备治疗肺脏纤维化药物中的应用 | 专利 | 王锐;谢俊秋;张邦治;蒋先兴;闫志斌;王丹 |
| 8 | Rapeseed protein-derived antioxidant peptide RAP alleviates renal fibrosis through MAPK/NF-kappa B signaling pathways in diabetic nephropathy | 期刊论文 | Zhang Mingyan;Yan Zhibin;Bu Lili;An Chunmei;Wang Dan;Liu Xin;Zhang Jianfeng;Yang Wenle;Deng Bochuan;Xie Junqiu;Zhang Bangzhi |
| 9 | 一种基于polybia-MPI的抗菌多肽化合物及其合成与应用 | 专利 | 张邦治;张剑锋;李晓;白路涛;高飞云;刘欢;李昊;曾庆芳;曹亦欣;李静 |
| 10 | 一种抗菌多肽化合物、合成方法及其应用 | 专利 | 张邦治;李晓;张剑锋;白路涛;高飞云;李昊;刘欢;曾庆芳;曹亦欣;李静 |
| 11 | 中国青年化学家元素周期表 | 奖励 | 杨东旭 |
| 12 | Protective effect of peptide DR8 on bleomycin-induced pulmonary fibrosis by regulating the TGF-beta/MAPK signaling pathway and oxidative stress | 期刊论文 | Wang Dan;Yan Zhibin;Bu Lili;An Chunmei;Deng Bochuan;Zhang Jianfeng;Rao Jing;Cheng Lu;Zhang Jingying;Zhang Bangzhi;Xie Junqiu |
| 13 | CPF-C1 analog with effective antimicrobial and antibiofilm activities against Staphylococcus aureus including MRSA | 期刊论文 | Junqiu Xie;Yao Li;Xiaomin Guo;Jing Rao;Tiantian Yan;Lingyun Mou;Xueping Wu;Xinxin Xie;Wenle Yang;Bangzhi Zhang |
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