海绵来源倍半萜醌类NF-κB抑制剂的发现及其抗肿瘤作用机制研究
41576130
2015
D0604.生物海洋学与海洋生物资源
焦伟华
面上项目
副研究员
上海交通大学
68万元
抗肿瘤;海绵;倍半萜醌;海洋天然产物;NF-κB抑制剂
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 倍半萜醌类化合物Dysiherbols A及其制备方法和用途 | 专利 | 林厚文;焦伟华 |
| 2 | Meroterpenoids with Protein Tyrosine Phosphatase 1B Inhibitory Activity from a Hyrtios sp. Marine Sponge | 期刊论文 | Jie Wang;Feng-Rong Mu;Wei-Hua Jiao;Jian Huang;Li-Li Hong;Fan Yang;Ying Xu;Shu-Ping Wang;Fan Sun;Hou-Wen Lin |
| 3 | Discovery of Nitrogenous Sesquiterpene Quinone Derivatives from Sponge Dysidea septosa with Anti-inflammatory Activity in vivo Zebrafish Model | 期刊论文 | Yu-Han Gui;Li Liu;Wei Wu;Yun Zhang;Zhi-Li Jia;Yong-Ping Shi;Hao-Tian Kong;Ke-Chun Liu;Wei-Hua Jiao;Hou-Wen Lin |
| 4 | Popolohuanones G-I, Dimeric Sesquiterpene Quinones with IL-6 Inhibitory Activity from the Marine Sponge Dactylospongia elegans | 期刊论文 | Jing Li;Wei Wu;Fan Yang;Li Liu;Shu-Ping Wang;Wei-Hua Jiao;Shi-Hai Xu;Hou-Wen Lin |
| 5 | Trivirensols: Selectively Bacteriostatic Sesquiterpene Trimers from the Australian Termite Nest-derived Fungus Trichoderma virens CMB-TN16 | 期刊论文 | Wei-Hua Jiao;Angela Salim;Zeinab Khalil;Pradeep Dewapriya;Hou-Wen Lin;Mark Butler;Robert J. Capon |
| 6 | 海绵来源杂萜类化合物Dysiarenone及其制备方法与应用 | 专利 | 焦伟华;林厚文;李静;石国华 |
| 7 | Dysiarenone, a Dimeric C21 Meroterpenoid with Inhibition of COX-2 Expression from the Marine Sponge Dysidea arenaria | 期刊论文 | Wei-Hua Jiao;Bao-Hui Cheng;Guo-Dong Chen;Guo-Hua Shi;Jing Li;Tian-Yong Hu;Hou-Wen Lin |
| 8 | 一种海绵来源杂萜类化合物及其制备方法与应用 | 专利 | 焦伟华;林厚文;桂语晗 |
| 9 | Bioactive sesquiterpene quinols and quinones from the marine sponge Dysidea avara | 期刊论文 | Wei-Hua Jiao;Ting-Ting Xu;Bin-Bin Gu;Guo-Hua Shi;Yan Zhu;Fan Yang;Bing-Nan Han;Shu-Ping Wang;Yu-Shan Li;Wei Zhang;Jia Li;Hou-Wen Lin |
| 10 | Divirensols: Sesquiterpene Dimers from the Australian Termite Nest-derived Fungus Trichodema virens CMB-TN16 | 期刊论文 | Wei-Hua Jiao;Pradeep Dewapriya;Osama Mohamed;Zeinab G. Khalil;Angela A. Salim;Hou-Wen Lin;Robert J. Capon |
| 11 | Unusual Anti-inflammatory Meroterpenoids from the Marine Sponge Dactylospongia sp. | 期刊论文 | Jing Li;Fan Yang;Zhuo Wang;Wei Wu;Li Liu;Shu-Ping Wang;Bin-Xin Zhao;Wei-Hua Jiao;Shi-Hai Xu;Hou-Wen Lin |
| 12 | Dysivillosins A–D, Unusual Anti-allergic Meroterpenoids from the Marine Sponge Dysidea villosa | 期刊论文 | Wei-Hua Jiao;Bao-Hui Cheng;Guo-Hua Shi;Guo-Dong Chen;Bin-Bin Gu;Yong-Jun Zhou;Li-Li Hong;Fan Yang;Zhi-Qiang Liu;Shu-Qi Qiu;Zhi-Gang Liu;Ping-Chang Yang;Hou-Wen Lin |
| 13 | Spiroetherones A and B, Sesquiterpene Naphthoquinones as Angiogenesis Inhibitors from the Marine Sponge Dysidea etheria | 期刊论文 | Wei-Hua Jiao;Qi-Hang Xu;Jie Cui;Ru-Yi Shang;Yun Zhang;Jia-Bao Sun;Qi Yang;Ke-Chun Liu;Hou-Wen Lin |
| 14 | Frondoplysins A and B, Unprecedented Terpene-Alkaloid Bioconjugates from Dysidea frondosa | 期刊论文 | Wei-Hua Jiao;Jing Li;Meng-Meng Zhang;Jie Cui;Yu-Han Gui;Yun Zhang;Jing-Ya Li;Ke-Chun Liu;Hou-Wen Lin |
| 15 | Cinerols, Nitrogenous Meroterpenoids from the Marine Sponge Dysidea cinerea | 期刊论文 | Wei-Hua Jiao;Jing Li;Dan Wang;Meng-Meng Zhang;Li-Yun Liu;Fan Sun;Jing-Ya Li;Robert J. Capon;Hou-Wen Lin |
| 16 | Dysiherbols A−C and Dysideanone E, Cytotoxic and NF-κB Inhibitory Tetracyclic Meroterpenes from a Dysidea sp. Marine Sponge | 期刊论文 | Wei-Hua Jiao;Guo-Hua Shi;Ting-Ting Xu;Guo-Dong Chen;Bin-Bin Gu;Zhuo Wang;Shuang Peng;Shu-Ping Wang;Jia Li;Bing-Nan Han;Wei Zhang;Hou-Wen Lin |
| 17 | (±)-Hippolide J – A Pair of Unusual Antifungal Enantiomeric Sesterterpenoids from the Marine Sponge Hippospongia lachne | 期刊论文 | Wei-Hua Jiao;Li-Li Hong;Jia-Bao Sun;Shu-Juan Piao;Guo-Dong Chen;Hai Deng;Shu-Ping Wang;Fan Yang;Hou-Wen Lin |
| 18 | Pellynols M-O, Cytotoxic Polyacetylenic Alcohols from a Niphates sp. Marine Sponge | 期刊论文 | Jie Wang;Li-Yun Liu;Lei Liu;Kai-Xuan Zhan;Wei-Hua Jiao;Hou-Wen Lin |
| 19 | 中国南海海绵资源库构建与活性物质研究 | 奖励 | 林厚文;焦伟华;杨帆;于豪冰;周永军;孙凡;朴淑娟;王淑萍;廖洪泽;李蕾 |
| 20 | Septosones A-C, in vivo Anti-inflammatory Meroterpenoids with Rearranged Carbon Skeletons from the Marine Sponge Dysidea septosa | 期刊论文 | Yu-Han Gui;Wei-Hua Jiao;Mi Zhou;Yun Zhang;De-Quan Zeng;Hong-Rui Zhu;Ke-Chun Liu;Fan Sun;Hai-Feng Chen;Hou-Wen Lin |
| 21 | 海绵来源杂萜类化合物Dysiarenone及其制备方法与应用 | 专利 | 焦伟华;林厚文;李静;石国华 |
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