基于证候病机的逍遥散-肝郁脾虚证方证相关的生物学基础研究
81630104
2016
H31.中医学
陈家旭
重点项目
教授
北京中医药大学
275万元
生物学基础;肝郁脾虚证;方证相关;逍遥散
2017-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 李时珍《濒湖脉学》对中医脉学的传承与发展 | 期刊论文 | 赵方舟;刘玥芸;陈家旭 |
| 2 | Xiaoyaosan exerts antidepressant-like effects by regulating the functions of astrocytes and EAATs in the prefrontal cortex of mice. | 期刊论文 | Liu Yan;Ding Xiu-Fang;Wang Xin-Xing;Zou Xiao-Juan;Li Xiao-Juan;Liu Yue-Yun;Li Jie;Qian Xiu-Yun;Chen Jia-Xu |
| 3 | Involvement of Hepatic SHIP2 and PI3K/Akt Signalling in the Regulation of Plasma Insulin by Xiaoyaosan in Chronic Immobilization-Stressed Rats. | 期刊论文 | Pan Qiuxia;Wu Jiajia;Liu Yueyun;Li Xiaojuan;Chen Jiaxu |
| 4 | Xiaoyaosan regulates depression-related behaviors with physical symptoms by modulating Orexin A/OxR1 in the hypothalamus. | 期刊论文 | Hou Yajing;Liu Yueyun;Liu Chenyue;Yan Zhiyi;Ma Qingyu;Chen Jianbei;Zhang Man;Yan Qiuying;Li Xiaojuan;Chen Jiaxu |
| 5 | COVID-19疫情期间抑郁症与睡眠障碍的相关性研究 | 期刊论文 | 朱潇旭;杨芙蓉;邹小娟;李晓娟;陈家旭 |
| 6 | 基于“异病同治”探讨阴疽和癥瘕的辨治思路 | 期刊论文 | 张曼;闫秋莹;侯雅静;柳辰玥;陈剑北;陈家旭;肖飞;裴学军 |
| 7 | Oral coniferyl ferulate attenuated depression symptoms in mice via reshaping gut microbiota and microbial metabolism. | 期刊论文 | Hao Wen-Zhi;Ma Qing-Yu;Tao Gabriel;Huang Jun-Qing;Chen Jia-Xu |
| 8 | 基于数据挖掘的中医药治疗产后抑郁症用药规律探讨 | 期刊论文 | 许梦白;刘雁峰;焦海燕;董硕;周璐;陈家旭 |
| 9 | Integrating Clinical and Genomic Analyses of Hippocampal-Prefrontal Circuit Disorder in Depression. | 期刊论文 | Yuan Naijun;Tang Kairui;Da Xiaoli;Gan Hua;He Liangliang;Li Xiaojuan;Ma Qingyu;Chen Jiaxu |
| 10 | 从“动则生阳”论治抑郁症的理论探索 | 期刊论文 | 雷超芳;陈志刚;王喜红;陈剑北;薛哲;刘玥芸;陈家旭 |
| 11 | 《伤寒杂病论》针刺条文及穴位探究 | 期刊论文 | 董硕;周可林;陈家旭 |
| 12 | Xiaoyaosan Improves Antibiotic-Induced Depressive-Like and Anxiety-Like Behavior in Mice Through Modulating the Gut Microbiota and Regulating the NLRP3 Inflammasome in the Colon. | 期刊论文 | Hao Wenzhi;Wu Jiajia;Yuan Naijun;Gong Lian;Huang Junqing;Ma Qingyu;Zhu Huizheng;Gan Hua;Da Xiaoli;Deng Lijuan;Li Xiaojuan;Chen Jiaxu |
| 13 | 从气血理论探讨癥瘕与阴疽病因病机的联系 | 期刊论文 | 闫秋莹;张曼;侯雅静;陈剑北;陈家旭;肖飞;裴学军 |
| 14 | 探讨证本质研究在完善中医辨证论治体系中的意义 | 期刊论文 | 李晓娟;陈家旭;刘玥芸 |
| 15 | Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress. | 期刊论文 | Ding Fengmin;Wu Jiajia;Liu Chenyue;Bian Qinglai;Qiu Wenqi;Ma Qingyu;Li Xiaojuan;Long Man;Zou Xiaojuan;Chen Jiaxu |
| 16 | 阴疽辨治的讨论 | 期刊论文 | 李晓娟;王方方;侯雅静;马庆宇;陈家旭;肖飞;裴学军 |
| 17 | 产后抑郁症中医研究进展 | 期刊论文 | 许梦白;刘雁峰;陈家旭 |
| 18 | An Integrated Pharmacology-Based Analysis for Antidepressant Mechanism of Chinese Herbal Formula Xiao-Yao-San. | 期刊论文 | Yuan Naijun;Gong Lian;Tang Kairui;He Liangliang;Hao Wenzhi;Li Xiaojuan;Ma Qingyu;Chen Jiaxu |
| 19 | 基于数据挖掘的针药结合治疗抑郁症临床规律分析 | 期刊论文 | 杨娜婷;唐凯锐;郭郁;陈家旭 |
| 20 | 从疽证论治现代疾病及小金丹应用延展专题介绍 | 期刊论文 | 侯雅静;刘玥芸;李晓娟;陈家旭;肖飞 |
| 21 | 抑郁症动物模型及中医药复方防治进展 | 期刊论文 | 笪晓丽;李晓娟;邱文琪;陈家旭 |
| 22 | Evaluating the Anti-depression Effect of Xiaoyaosan on Chronically-stressed Mice. | 期刊论文 | Yan Zhi-Yi;Li Xiao-Juan;Ding Xiu-Fang;Liu Yue-Yun;Chen Jia-Xu |
| 23 | “三基辨证”体系的提出及其理论渊源 | 期刊论文 | 赵宗耀;陈家旭 |
| 24 | 肝脏象现代研究重要发现述评 | 期刊论文 | 侯雅静;陈家旭;李晓娟 |
| 25 | 基于扎根理论与内容分析法的肝郁证候定性与定量研究方法探析 | 期刊论文 | 郝闻致;龚炼;薛飞飞;陈家旭 |
| 26 | Study on urinary metabolomics of premenstrual dysphoric disorder patients with liver-qi depression syndrome treated with Xiaoyaosan: Study Protocol Clinical Trial (SPIRIT Compliant). | 期刊论文 | Xu Mengbai;Liu Yanfeng;Guo Yu;Liu Chenyue;Liu Yueyun;Yan Zhiyi;Hou Yajing;Li Xiaojuan;Ma Qingyu;Zhou Xuan;Liu Liuqing;Huang Sheng;Chen Jiaxu |
| 27 | 从阴疽论治多囊卵巢综合征 | 期刊论文 | 赵宗耀;侯雅静;闫秋莹;张曼;陈剑北;柳辰玥;陈家旭;肖飞;裴学军 |
| 28 | 浅析三焦的重要性 | 期刊论文 | 李杰;侯雅静;柳辰玥;张曼;陈剑北;陈家旭 |
| 29 | 《诸病源候论》"候"的特点及其临床意义 | 期刊论文 | 郝闻致;李晓娟;陈家旭 |
| 30 | “善太息”五证辨析 | 期刊论文 | 朱潇旭;杨芙蓉;李晓娟;鄢黎;邹小娟;李澜;陈家旭 |
| 31 | 线粒体功能障碍与抑郁症发病关系的研究进展 | 期刊论文 | 朱潇旭;邹小娟;杨芙蓉;卞庆来;陈家旭 |
| 32 | 《傅青主女科》情志致病辨治初探 | 期刊论文 | 许梦白;刘雁峰;陈家旭 |
| 33 | 从"异病同治"探讨小金丹在乳腺增生症的应用 | 期刊论文 | 吴佳佳;陈家旭;肖飞;裴学军 |
| 34 | Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling. | 期刊论文 | Li Xiaojuan;Qiu Wenqi;Li Nan;Da Xiaoli;Ma Qingyu;Hou Yajing;Wang Tingye;Song Ming;Chen Jiaxu |
| 35 | A review of antibiotics, depression, and the gut microbiome. | 期刊论文 | Hao Wen-Zhi;Li Xiao-Juan;Zhang Pei-Wen;Chen Jia-Xu |
| 36 | 基于“三基辨证”的证名规范化 | 期刊论文 | 赵宗耀;陈家旭 |
| 37 | 逍遥散抗抑郁和抗焦虑研究进展 | 期刊论文 | 李晓娟;陈家旭;周雪明;王亭晔;宋明;侯雅静;王方方 |
| 38 | 浅谈中医四诊的延伸 | 期刊论文 | 钱秀云;柳辰玥;李杰;刘燕;陈家旭 |
| 39 | Traditional Chinese Formula Xiaoyaosan Alleviates Depressive-Like Behavior in CUMS Mice by Regulating PEBP1-GPX4-Mediated Ferroptosis in the Hippocampus. | 期刊论文 | Jiao Haiyan;Yang Hongjun;Yan Zhiyi;Chen Jianbei;Xu Mengbai;Jiang Youming;Liu Yueyun;Xue Zhe;Ma Qingyu;Li Xiaojuan;Chen Jiaxu |
| 40 | 一种四诊信息权重分析的中医辨证系统及其方法 | 专利 | 赵宗耀;陈家旭;刘玥芸;闫秋莹;张曼;侯雅静;柳辰玥;陈剑北 |
| 41 | 肠道微生态与中医证候的相关性研究概况 | 期刊论文 | 吴佳佳;李晓娟;陈家旭 |
| 42 | P2X2受体在肝郁脾虚证小鼠模型前额皮质中的表达 | 期刊论文 | 刘燕;丁秀芳;严志祎;李晓娟;刘玥芸;邹小娟;丁凤敏;余涛;陈家旭 |
| 43 | Xiaoyaosan exerts anxiolytic-like effects by down-regulating the TNF-alpha/JAK2-STAT3 pathway in the rat hippocampus | 期刊论文 | Li Xiao-Juan;Ma Qing-Yu;Jiang You-Ming;Bai Xiao-Hui;Yan Zhi-Yi;Liu Qun;Pan Qiu-Xia;Liu Yue-Yun;Chen Jia-Xu |
| 44 | 探讨DHEA对闭锁卵泡形成的机制 | 期刊论文 | 张海甄;翁嘉敏;史惠媚;吴佳琳;朱文俊;高梓博;杨舒含;梁卓潼;陈家旭 |
| 45 | 基于《四圣心源》探讨奔豚的三型四期论治 | 期刊论文 | 董硕;周可林;陈家旭 |
| 46 | 基于文献分析的围绝经期综合征证候规范化模型构建 | 期刊论文 | 郝闻致;龚炼;薛飞飞;陈家旭 |
| 47 | 小金丹治疗慢性盆腔炎的理论探讨 | 期刊论文 | 许梦白;刘雁峰;陈家旭;肖飞;裴学军 |
| 48 | 小金丹治疗阴疽病机特点探析 | 期刊论文 | 侯雅静;陈剑北;张曼;闫秋莹;赵宗耀;陈家旭;肖飞;裴学军 |
| 49 | 抑郁症与肝肾相关性探讨 | 期刊论文 | 陈剑北;卞庆来;宋美芳;陈家旭 |
| 50 | Antidepressant Mechanism of Traditional Chinese Medicine Formula Xiaoyaosan in CUMS-Induced Depressed Mouse Model via RIPK1-RIPK3-MLKL Mediated Necroptosis Based on Network Pharmacology Analysis. | 期刊论文 | Yan Zhi-Yi;Jiao Hai-Yan;Chen Jian-Bei;Zhang Kai-Wen;Wang Xi-Hong;Jiang You-Ming;Liu Yue-Yun;Xue Zhe;Ma Qing-Yu;Li Xiao-Juan;Chen Jia-Xu |
| 51 | Effects of histone modification in major depressive disorder. | 期刊论文 | Wu Man-Si;Li Xiao-Juan;Liu Chen-Yue;Xu Qiuyue;Huang Jun-Qing;Gu Simeng;Chen Jia-Xu |
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