HPV16 E6/E7介导HIF-1α上调肺癌细胞GLUT1表达的分子机制

81672082
2016
H2603.细胞学和血液学检验
吴广平
面上项目
教授
中国医科大学
50万元
缺氧诱导因子-1α;临床细胞学;人乳头瘤病毒;肺癌;葡萄糖转运蛋白1
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation 期刊论文 Tang JY;Li DY;He L;Qiu XS;Wang EH;Wu GP
2 Human papillomavirus 16 (HPV 16) E6 but not E7 inhibits the antitumor activity of LKB1 in lung cancer cells by downregulating the expression of KIF7. 期刊论文 Hu Y;Wu MZ;Gu NJ;Xu HT;Li QC;Wu GP
3 HPV 16 E6/E7 up-regulate the expression of both HIF-1α and GLUT1 by inhibition of RRAD and activation of NF-κB in lung cancer cells 期刊论文 Gu NJ;Wu MZ;He L;Wang XB;Wang S;Qiu XS;Wang EH;Wu GP
4 Comparative Analysis for Diagnostic Yield of Small Cell Lung Cancer by Cytology and Histology During the Same Bronchoscopic Procedure 期刊论文 Li Wei Nan;Wang Di Fei;Zhao Ya Bin;Qiu Xue Shan;Wang En Hua;Wu Guang Ping
5 Diagnostic Utility of HPV16 E6 mRNA or E7 mRNA Quantitative Expression for Cervical Cells of Patients with Dysplasia and Carcinoma 期刊论文 Wu MZ;Li WN;Cha N;Tian LX;Zhang YI;Wu X;Guo KJ;Guangping Wu
6 HPV16 E6/E7 upregulates HIF-2 alpha and VEGF by inhibiting LKB1 in lung cancer cells 期刊论文 Shao Jian-Shuang;Sun Jian;Wang Shiyu;Chung Katherine;Du Jin Tong;Wang Jason;Qiu Xue-Shan;Wang En-Hua;Wu Guang-Ping
7 The Diagnostic Utility of p16 Immunostaining in Differentiating Cancer and HSIL from LSIL and Benign in Cervical Cells 期刊论文 Wu MZ;Wang S;Zheng M;Tian LX;Wu X;Guo KJ;Zhang Y;Guangping Wu
8 The Morphological Analysis of Cells in the Peritoneal Washing Fluids of Patients with Gastric Cancer 期刊论文 Jiang RP;Xiong XJ;Qiu XS;Wang EH;Wu GP
9 HPV16 E6/E7 upregulate hTERC mRNA and gene amplification levels by relieving the effect of LKB1 on Sp1 phosphorylation in lung cancer cells 期刊论文 Yang JH;Wu MZ;Wang XB;Wang S;Qiu XS;Wang EH;Wu GP
10 The Morphological Analysis of Cells in the Bronchoscopic Brushing and TBNA of Patients with Lung Adenocarcinoma 期刊论文 Xiao MM;Zhao YB;Liu DG;Qiu XS;Wang EH;Guang-Ping Wu
11 Analysis of human papillomavirus 16 E6/E7 and L1 in the bronchial brushing cells of patients with squamous cell carcinoma of the lungs 期刊论文 Huan-Yu Zhao;Jing-Hua Yang;Xin Wang;Jian Sun;En-Hua Wang;Guang-Ping Wu
12 Long-term persistent infection of HPV 16 E6 up-regulate SP1 and hTERT by inhibiting LKB1 in lung cancer cells 期刊论文 Yang Jing-Hua;Li Xiao-Yan;Wang Xin;Hou Wei-Jian;Qiu Xue-Shan;Wang En-Hua;Wu Guang-Ping
13 Tumor Suppressor LKB1 inhibits both the mRNA Expression and the Amplification of hTERC by the Phosphorylation of YAP in Lung Cancer Cells 期刊论文 He L;Wu MZ;Wang XB;Qiu XS;Wang EH;Wu GP
14 HPV16 E6/E7 promote the translocation and glucose uptake of GLUT1 by PI3K/AKT pathway via relieving miR-451 inhibitory effect on CAB39 in lung cancer cells. 期刊论文 Wang HM;Lu YJ;He L;Gu NJ;Wang SY;Qiu XS;Wang EH;Wu GP
15 Diagnostic value of acid phosphatases (ACP) in differentiating reactive mesothelial cells from cancer cells in the body fluid effusions 期刊论文 Yun-Hui Li;Yang Wang;Xiu-Xia Chen;Bin Liang;Xue-Shan Qiu;En-Hua Wang;Guang-Ping Wu
16 Dact3 inhibits the malignant phenotype of non-small cell lung cancer through downregulation of c-Myb 期刊论文 Huanyu Zhao;Lianhe Yang;Yang Han;Hongqiang Li;Zihan Ling;Yan Wang;Enhua Wang;Guangping Wu
17 Glucose Transporter 1 Promotes the Malignant Phenotype of Non-Small Cell Lung Cancer through Integrin β1/Src/FAK Signaling 期刊论文 Zhao H;Sun J;Shao J;Zou Z;Qiu X;Wang E;Wu G
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