磷硫酰化修饰保护DNA免于切割的分子机理研究

31872627
2018
C0102.微生物生理与生化
吴更
面上项目
教授
上海交通大学
59万元
活性反应中心;核酸酶;底物结合中心;底物识别机制;催化机制
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Structural analysis of an L-cysteine desulfurase from an Ssp DNA phosphorothioation system. 期刊论文 Liu L;Jiang S;Xing M;Chen C;Lai C;Li N;Liu G;Wu D;Gao H;Hong L;Tan P;Chen S;Deng Z;Wu G;Wang L
2 Structural, Mechanistic, and Functional Insights into an Arthrobacter nicotinovorans Molybdenum Hydroxylase Involved in Nicotine Degradation 期刊论文 Wang L;Mu X;Li W;Xu Q;Xu P;Zhang L;Zhang Y;Wu G
3 Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. 期刊论文 Gao H;Gong X;Zhou J;Zhang Y;Duan J;Wei Y;Chen L;Deng Z;Wang J;Chen S;Wu G;Wang L
4 SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities. 期刊论文 Xiong X;Wu G;Wei Y;Liu L;Zhang Y;Su R;Jiang X;Li M;Gao H;Tian X;Zhang Y;Hu L;Chen S;Tang Y;Jiang S;Huang R;Li Z;Wang Y;Deng Z;Wang J;Dedon PC;Chen S;Wang L
5 Mathematical appraisal of SARS-CoV-2 Omicron epidemic outbreak in unprecedented Shanghai lockdown 期刊论文 Jiang M;Yin H;Zhang S;Meng G;Wu G
6 Architecture of the Tuberous Sclerosis Protein Complex. 期刊论文 Ramlaul K;Fu W;Li H;Garrido NM;He L;Cui W;Aylett CHS;Wu G
7 DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analyses 期刊论文 Yu H;Li J;Liu G;Zhao G;Wang Y;Hu W;Deng Z;Wu G;Gan J;Zhao YL;He X
8 Structural insight into the recognition between Sufu and fused in the Hedgehog signal transduction pathway 期刊论文 Li H;Wang W;Zhang W;Wu G
9 The functional coupling between restriction and DNA phosphorothioation modification systems underlying the DndFGH restriction complex. 期刊论文 Wu D;Tang Y;Chen S;He Y;Chang X;Zheng W;Deng Z;Li Z;Wang L;Wu G;Chen S
10 The Osa-Containing SWI/SNF Chromatin-Remodeling Complex Is Required in the Germline Differentiation Niche for Germline Stem Cell Progeny Differentiation 期刊论文 Hu X;Li M;Hao X;Lu Y;Zhang L;Wu G
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