鸭RIG-I和MDA5介导并依赖于STING的天然免疫双通路的激活与调控机制
31872456
2018
C1804.兽医免疫学
孙建和
面上项目
教授
上海交通大学
60万元
黑色素瘤分化相关基因５;模式识别受体;干扰素基因刺激因子;家禽;维甲酸诱导基因蛋白I
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Goose IRF7 is involved in antivirus innate immunity by mediating IFN activation | 期刊论文 | Zhenyu Lin;Jie Wang;Shurui Zhao;Yanlin Li;Yanhe Zhang;Yue Wang;Yaxian Yan;Yuqiang Cheng;Jianhe Sun |
| 2 | Functional characterization of goose IRF1 in IFN induction and anti-NDV infection | 期刊论文 | Zhenyu Lin;Jie Wang;Nian Zhang;Jianshu Yi;Zhaofei Wang;Jingjiao Ma;Hengan Wang;Yaxian Yan;Kun Qian;Jianhe Sun;Yuqiang Cheng |
| 3 | Chicken miR-126-5p negatively regulates antiviral innate immunity by targeting TRAF3 | 期刊论文 | Jie Wang;Yuqiang Cheng;Longlong Wang;Aixi Sun;Zhenyu Lin;Wenxian Zhu;Zhaofei Wang;Jingjiao Ma;Henan Wang;Yaxian Yan;Jianhe Sun |
| 4 | Chicken DDX1 Acts as an RNA Sensor to Mediate IFN-β Signaling Pathway Activation in Antiviral Innate Immunity | 期刊论文 | Zhenyu Lin;Jie Wang;Wenxian Zhu;Xiangyu Yu;Zhaofei Wang;Jingjiao Ma;Hengan Wang;Yaxian Yan;Jianhe Sun;Yuqiang Cheng |
| 5 | 靶向敲除鸡IRF7基因的方法及其在疫苗制备中的应用 | 专利 | 孙建和;程玉强;伦敏翔;严亚贤 |
| 6 | Chicken DDX3X Activates IFN-β via the chSTING-chIRF7-IFN-β Signaling Axis | 期刊论文 | Qiaona Niu;Yuqiang Cheng;Hengan Wang;Yaxian Yan;Jianhe Sun |
| 7 | IRF7 Is Involved in Both STING and MAVS Mediating IFN- beta Signaling in IRF3-Lacking Chickens | 期刊论文 | Cheng Yuqiang;Zhu Wenxian;Ding Chan;Niu Qiaona;Wang Hengan;Yan Yaxian;Sun Jianhe |
| 8 | CRISPR/Cas9-Mediated Chicken TBK1 Gene Knockout and Its Essential Role in STING-Mediated IFN-beta Induction in Chicken Cells | 期刊论文 | Cheng Yuqiang;Lun Minxiang;Liu Yunxia;Wang Hengan;Yan Yaxian;Sun Jianhe |
| 9 | Functional Characterization of Duck STING in IFN-β Induction and Anti-H9N2 Avian Influenza Viruses Infections | 期刊论文 | Yuqiang Cheng;Yunxia Liu;Shuduan Shi;Qiaona Niu;Wenxian Zhu;Zhaofei Wang;Jingjiao Ma;Hengan Wang;Yaxian Yan;Jianhe Sun |
| 10 | The identification of a shorter cyclic GMP-AMP synthase gene from chickens and bioinformatics analysis of its potential signaling in IFN regulation | 期刊论文 | Wenxian Zhu;Yuqiang Cheng;Zhaofei Wang;Likai Ji;Jingjiao Ma;Yaxian Yan;Hengan Wang;Jianhe Sun |
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