神经特异性O-GalNAc糖基转移酶在内质网中的功能机制研究

31770850
2017
C0506.糖、脂生物化学
张延
面上项目
教授
上海交通大学
64万元
神经元分化;糖蛋白分泌;内质网流动性;O-糖基化修饰;糖基转移酶
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Polypeptide N-acetylgalactosaminyltransferase 18 non-catalytically regulates the ER homeostasis and O-glycosylation 期刊论文 Shan Aidong;Lu Jishun;Xu Zhijue;Li Xing;Xu Yingjiao;Li Wei;Liu Feng;Yang Fang;Sato Takashi;Narimatsu Hisashi;Zhang Yan
2 Regulatory Role of One Critical Catalytic Loop of Polypeptide N-Acetyl-Galactosaminyltransferase-2 in Substrate Binding and Catalysis during Mucin-Type O-Glycosylation 期刊论文 Tian Jiaqi;Liu Feng;Xu Zhijue;Shi Jingjing;Liang Tao;Zhang Yan;Da Lin Tai
3 O-linked N-acetylgalactosamine (O-GalNAc) glycosylation is present on the tumor suppressor p53 会议论文 许之珏;刘峰;崔雅璐;张延
4 Glycomic Signatures of Plasma IgG Improve Preoperative Prediction of the Invasiveness of Small Lung Nodules 期刊论文 Zou Xia;Yao Feng;Yang Fang;Zhang Fang;Xu Zhijue;Shi Jingjing;Kuno Atsushi;Zhao Heng;Zhang Yan
5 Comprehensive analysis of O-glycosylation of amyloid precursor protein (APP) using targeted and multi-fragmentation MS strategy. 期刊论文 Shi Jingjing;Ku Xin;Zou Xia;Hou Jingli;Yan Wei;Zhang Yan
6 O-glycoproteomic analysis of proteinsregulated by ppGalNAc-T13 during neural differentiation in P19 embryonal carcinoma cells. 会议论文 邓陶;刘倩楠;贾文娟;邹霞;张延
7 Databases and Bioinformatic Tools for Glycobiology and Glycoproteomics 期刊论文 Li Xing;Xu Zhijue;Hong Xiaokun;Zhang Yan;Zou Xia
8 Characterization and application of a monoclonal antibody 1J5 against ppGalNAc-T13 会议论文 贾文娟;徐颖姣;许之珏;崔雅璐;张延
9 疾病及发育中多肽:N-乙酰氨基半乳糖转移酶ppGalNAc-T的重要性 期刊论文 崔雅璐;徐颖姣;贾文娟;杨芳;张延
10 The interactome of ppGalNAc-T18 in ER plays a role in its ER retention 会议论文 贾文娟;许之珏;单爱东;张延
11 一种制备N-乙酰氨基半乳糖转移酶的方法 专利 张延;梁涛;许之珏;贾文娟
12 The polypeptide N-acetylgalactosaminyltransferase 4 exhibits stage-dependent expression in colorectal cancer and affects tumorigenesis, invasion and differentiation 期刊论文 Yan Xialin;Lu Jishun;Zou Xia;Zhang Sen;Cui Yalu;Zhou Leqi;Liu Feng;Shan Aidong;Lu Jiaoyang;Zheng Minghua;Feng Bo;Zhang Yan
13 ppGalNAc-T靶向抑制剂在APP蛋白质O-GalNAc糖基化功能研究中的应用 会议论文 刘峰;许之珏;李星;张延
14 O-linked N-acetylgalactosamine modification is present on the tumor suppressor p53 期刊论文 Xu Zhijue;Ku Xin;Tomioka Azusa;Xie Wenxian;Liang Tao;Zou Xia;Cui Yalu;Sato Takashi;Kaji Hiroyuki;Narimatsu Hisashi;Yan Wei;Zhang Yan
15 用于表达黏蛋白型O-糖基化蛋白的原核载体和系统、黏蛋白型O-糖基化蛋白的制备方法 专利 张延;张涵;许之珏;杨芳
16 Inhibition of polypeptide N-acetyl-alpha-galactosaminyltransferases is an underlying mechanism of dietary polyphenols preventing colorectal tumorigenesis 期刊论文 Liu Feng;Cui Yalu;Yang Fang;Xu Zhijue;Da Lin Tai;Zhang Yan
17 Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1. 期刊论文 Jia Wenjuan;Zou Xia;Xu Zhijue;Bai Lin;Shan Aidong;Li Yankun;Shi Jingjing;Yang Fang;Ding Chen;Narimatsu Hisashi;Zhang Yan
18 一种制备N-乙酰氨基半乳糖转移酶的方法 专利 张延;梁涛;许之珏;贾文娟
19 血清免疫球蛋白G糖链修饰在肺部磨玻璃结节早期诊断中的用途 专利 张延;张芳;许之珏;杨芳;邹霞;姚烽;赵珩
20 A simple bacterial expression system for human ppGalNAc-T and used for the synthesis of O-GalNAc glycosylated interleukin 2 期刊论文 Liang Tao;Xu Zhijue;Jia Wenjuan;Zhang Han;Yang Fang;Zou Xia;Zhang Yan
21 The beta-galactoside alpha 2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation 期刊论文 Zhou Leqi;Zhang Sen;Zou Xia;Lu Jishun;Yang Xiao;Xu Zhijue;Shan Aidong;Jia Wenjuan;Liu Feng;Yan Xialin;Su Hao;Liang Tao;Zheng Minhua;Zhang Yan;Feng Bo
22 O-glycosylation of Amyloid Precursor Protein(APP) Modulates Localization of App and Aβ Generation 会议论文 史婧婧;刘峰;邹霞;张延
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