不同生理/病理状态下谷胱甘肽抗氧化系统对吡咯里西啶生物碱肝毒性的影响及其机制

30801544
2008
H3217.中药毒理
季莉莉
青年科学基金项目
研究员
上海中医药大学
20万元
凋亡信号通路;生理/病理状态;吡咯里西啶生物碱;GSH抗氧化系统
2009-01-01到2011-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Influence on brain level of glutathione and activities of glutathione-related enzymes in tumor-bearing mice. 期刊论文 Chen Ying |Yu Qianming |Ji Lili |Wang Zhengtao |Shen Kaikai |
2 Intracellular glutathione plays important roles in pyrrolizidine alkaloids-induced growth inhibition on hepatocytes 期刊论文 Chen Ying|Wang Haitao|Ji Lili|Wang Zhengtao|
3 Pyrrolizidine alkaloid clivorine induced oxidative injury on primary cultured rat hepatocytes 期刊论文 Wang ZhengTao|Ji Lili|Liu TianYu|
4 Evaluation of gender-related differences in various oxidative stress enzymes in mice 期刊论文 Wang Zhengtao |Chen Ying |Liu Tianyu |Ji Lili |
5 The difference of glutathione antioxidant system in newly weaned and young mice liver and its involvement in isoline-induced hepatoxicity 期刊论文 Wang Zhengtao |Liang Qingning |Jiang Ping |Min Yang |Sheng Yuchen |Ji Lili |Xia Yuye |
6 Pyrrolizidine alkaloid isoline-induced oxidative injury in various mouse tissues 期刊论文 Liu Tianyu|Wang Zaiyong|Ji Lili|Wang Zhengtao|Chen Ying|
7 Protective Mechanisms of N-Acetyl-Cysteine Against Pyrrolizidine Alkaloid Clivorine-Induced Hepatotoxicity 期刊论文 Liu Tianyu|Chen Ying|Ji Lili|Wang Zhengtao|
8 Pyrrolizidine alkaloid clivorine induced oxidative stress injury in human normal liver L-02 cells 期刊论文 Min Yang |Liu Tianyu|Xia Yuye |Ji Lili |Liang Qingning |
9 不同年龄小鼠脑组织中谷胱甘肽系统的比较 期刊论文 夏玉叶|闵旸|蒋萍|盛雨辰|季莉莉|梁青宁|
10 The gender-dependent difference of liver GSH antioxidant system in mice and its influence on isoline-induced liver injury 期刊论文 Liang Qingning | Wang Zhengtao|Min Yang |Jiang Ping |Sheng Yuchen |Ji Lili |Xia Yuye |
11 Acetaminophen-induced cytotoxicity on human normal liver L-02 cells and the protection of antioxidants 期刊论文 Sheng Yuchen|Ji Lili|Min Yang|Liang Qingning|Xia Yuye|Wang Zhengtao|
12 Protection of Epidermal Growth Factor Against Clivorine-Induced Mitochondrial-Mediated Apoptosis in Hepatocytes 期刊论文 Liu Tianyu|Ji Lili|Wang Zhengtao|
13 6种黄酮类化合物拮抗肝细胞毒性作用的比较 期刊论文 王再勇|杨阳|季莉莉|周桂琼|王峥涛|
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