结核亚单位疫苗诱导的记忆性T细胞亚型特征、分化调控及保护效应研究
31470895
2014
C0808.疫苗、抗体与免疫干预
祝秉东
面上项目
教授
兰州大学
80万元
结核病;效应记忆T细胞;免疫记忆;亚单位疫苗;中央记忆T细胞
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Multi-Stage Tuberculosis Subunit Vaccine Candidate LT69 Provides High Protection against Mycobacterium tuberculosis Infection in Mice | 期刊论文 | Niu Hongxia;Peng Jinxiu;Bai Chunxiang;Liu Xun;Luo Yanping;Yu Hongjuan;Zhu Bingdong;Niu Hongxia;Peng Jinxiu;Bai Chunxiang;Liu Xun;Luo Yanping;Yu Hongjuan;Zhu Bingdong;Niu Hongxia;Peng Jinxiu;Bai Chunxiang;Liu Xun;Zhu Bingdong;Hu Lina;Wang Bingxiang;Zhang Ying;Chen Jianzhu;Chen Jianzhu;Xian Qiaoyang;Zhu BD |
| 2 | IL-28B down-regulates regulatory T cells but does not improve the protective immunity following tuberculosis subunit vaccine immunization | 期刊论文 | Luo Yanping;Ma Xingming;Liu Xun;Lu Xiaoling;Niu Hongxia;Yu Hongjuan;Bai Chunxiang;Peng Jinxiu;Xian Qiaoyang;Wang Yong;Zhu Bingdong |
| 3 | 结核分枝杆菌融合蛋白EAMMH、其构建、表达和纯化方法及其应用 | 专利 | 祝秉东 |
| 4 | Tuberculosis vaccines: Opportunities and challenges | 期刊论文 | Zhu Bingdong;Zhu Bingdong;Dockrell Hazel M.;Dockrell Hazel M.;Ottenhoff Tom H. M.;Evans Thomas G.;Zhang Ying;Zhu BD;Zhu BD |
| 5 | 补肾健脾方干预PPD诱导小鼠T细胞耗竭的实验研究 | 期刊论文 | 甘超;李小平;刘勋;李菲;牛红霞;祝秉东 |
| 6 | A novel liposome adjuvant DPC mediates Mycobacterium tuberculosis subunit vaccine well to induce cell-mediated immunity and high protective efficacy in mice | 期刊论文 | Liu Xun;Da Zejiao;Wang Yue;Niu Hongxia;Li Ruiying;Yu Hongjuan;He Shanshan;Guo Ming;Wang Yong;Luo Yanping;Ma Xingming;Zhu Bingdong |
| 7 | A multistage mycobacterium tuberculosis subunit vaccine LT70 including latency antigen Rv2626c induces long-term protection against tuberculosis | 期刊论文 | Liu Xun;Peng Jinxiu;Hu Lina;Luo Yanping;Niu Hongxia;Bai Chunxiang;Wang Qian;Li Fei;Yu Hongjuan;Wang Bingxiang;Chen Huiyu;Guo Ming;Zhu Bingdong |
| 8 | 重组融合细胞因子IL-7-Linker-IL-15腺病毒及其构建和应用 | 专利 | 祝秉东 |
| 9 | 结核分枝杆菌蛋白亚单位疫苗与疫苗诱导的T细胞免疫记忆研究进展 | 期刊论文 | 祝秉东;马澜;刘勋;牛红霞;白春香;李菲 |
| 10 | Prolonged intervals during Mycobacterium tuberculosis subunit vaccine boosting contributes to eliciting immunity mediated by central memory-like T cells | 期刊论文 | Bai Chunxiang;He Juanjuan;Niu Hongxia;Luo Yanping;Liu Xun;Zhu Bingdong;Bai Chunxiang;He Juanjuan;Niu Hongxia;Luo Yanping;Liu Xun;Zhu Bingdong;He Juanjuan;Niu Hongxia;Liu Xun;Zhu Bingdong;Hu Lina;Luo Yanping;Peng Liang;Zhu BD |
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