源于天然源奎宁类生物碱的全新杀菌化学实体的设计合成与结构优化研究
21877056
2018
B0706.药物化学生物学
刘映前
面上项目
教授
兰州大学
68万元
杀菌活性;奎宁生物碱;设计合成;结构优化;构效关系
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Design, synthesis, and antifungal evaluation of neocryptolepine derivatives against phytopathogenic fungi | 期刊论文 | Jia-Kai Zhu;Jian-Mei Gao;Cheng-Jie Yang;Xiao-Fei Shang;Zhong-Min Zhao;Raymond Kobla Lawoe;Rui Zhou;Yu Sun;Xiao-Dan Yin;Ying-Qian Liu |
| 2 | Antifungal Exploration of Quinoline Derivatives against Phytopathogenic Fungi Inspired by Quinine Alkaloids | 期刊论文 | Yong-Jia Chen;Kun-Yuan Ma;Sha-Sha Du;Zhi-Jun Zhang;Tian-Lin Wu;Yu Sun;Ying-Qian Liu;Xiao-Dan Yin;Rui Zhou;Yin-Fang Yan |
| 3 | Design, Synthesis, and Antifungal Evaluation of Luotonin A Derivatives against Phytopathogenic Fungi | 期刊论文 | Ren-Xuan Wang;Sha-Sha Du;Jing-Ru Wang;Qing-Ru Chu;Chen Tang;Zhi-Jun Zhang;Cheng-Jie Yang;Ying-Hui He;Hai-Xing Li;Tian-Lin Wu;Ying-Qian Liu |
| 4 | Chapter One - Biology of quinoline and quinazoline alkaloids | 期刊论文 | Xiao-Fei Shang;Susan L.Morris-Natschke;Ying-Qian Liu;Xiu-Hui Li;Ji-Yu Zhang;Kuo-HsiungLee |
| 5 | 一种喹啉4-位羟基乙酯类化合物的制备及其在防治植物病害中的应用 | 专利 | 刘映前;彭静文;白银鹏;杨程杰;刘华;杨余东;朱佳凯 |
| 6 | 一种8-羟基喹啉配合物的制备及其在防治植物病害中的用途 | 专利 | 刘映前;尹晓丹;黄晓玲;孙钰;杨冠洲;李俊采;朱佳凯;刘华 |
| 7 | Design, synthesis and antifungal activity evaluation of isocryptolepine derivatives | 期刊论文 | Jun-cai Li;Ren-xuan Wang;Yu Sun;Jia-kai Zhu;Guan-fang Hu;Yu-ling Wang;Rui Zhou;Zhong-min Zhao;Ying-qian Liu;Jing-wen Peng;Yin-fang Yan;Xiao-fei Shang |
| 8 | Design, Synthesis, and Antifungal Evaluation of 8-Hydroxyquinoline Metal Complexes against Phytopathogenic Fungi. | 期刊论文 | Xiao-Dan Yin;Kun-Yuan Ma;Yu-Ling Wang;Yu Sun;Xiao-Fei Shang;Zhong-Min Zhao;Ren-Xuan Wang;Yong-Jia Chen;Jia-Kai Zhu;Ying-Qian Liu |
| 9 | 喹啉2-位衍生物在制备防治植物病害的药物中的应用 | 专利 | 刘映前;杨余东;张智军;赵中敏;彭静文;杨程杰;孙钰;吴天琳 |
| 10 | Synthesis and anti-phytopathogenic activity of 8- hydroxyquinoline derivatives | 期刊论文 | Xiao-Dan Yin;Yu Sun;Raymond Kobla Lawoe;Guan-Zhou Yang;Ying-Qian Liu;Xiao-Fei Shang;Hua Liu;Yu-Dong Yang;Jia-Kai Zhu;Xiao-Ling Huang |
| 11 | 一种骨架跃迁型小檗碱类似物及其在防治农业病害中的应用 | 专利 | 刘映前;杨程杰;吕卫鹏;崔艮中 |
| 12 | Design, Synthesis, and Antifungal Evaluation of Cryptolepine Derivatives against Phytopathogenic Fungi | 期刊论文 | Yong-Jia Chen;Hua Liu;Shao-Yong Zhang;Hu Li;Kun-Yuan Ma;Ying-Qian Liu;Xiao-Dan Yin;Rui Zhou;Yin-Fang Yan;Ren-Xuan Wang;Ying-Hui He;Qing-Ru Chu;Chen Tang |
| 13 | 一种吴茱萸碱类似物及其在防治植物病原真菌中的用途 | 专利 | 刘映前;杨程杰;吴天琳;王璟汝;李海昕;罗雄飞;贺颖慧;杜莎莎 |
| 14 | 一种2,8-双(三氟甲基)喹啉类4-位修饰的衍生物在防治植物病害中的用途 | 专利 | 刘映前;杨冠洲;燕银芳;李虎;朱佳凯;高建梅;尹晓丹 |
| 15 | 一种2,8-双(三氟甲基)-4-羟基喹啉衍生物在制备和防治农业病害中的用途 | 专利 | 刘映前;马鲲原;陈永甲;张智军;杜莎莎;贺颖慧;尹晓丹;王仁轩;李虎;楚庆如;唐晨;赵文斌;梁宏杰;杨程杰 |
| 16 | Design, Synthesis, and Structure−Activity Relationship of Quinazolinone Derivatives as Potential Fungicides | 期刊论文 | Jing-Wen Peng;Xiao-Dan Yin;Hu Li;Kun-Yuan Ma;Zhi-Jun Zhang;Rui Zhou;Yu-Ling Wang;Guan-Fang Hu;Ying-Qian Liu |
| 17 | Design, synthesis, and biological evaluation of novel berberine derivatives against phytopathogenic fungi | 期刊论文 | Yong Zhou;Cheng-Jie Yang;Xiong-Fei Luo;An-Ping Li;Shao-Yong Zhang;Jun-Xia An;Zhi-Jun Zhang;Yue Ma;Bao-Qi Zhang;Ying-Qian Liu |
| 18 | Design, synthesis, and antifungal evaluation of novel quinoline derivatives inspired from natural quinine alkaloids | 期刊论文 | Guan-Zhou Yang;Jia-Kai Zhu;Xiao-Dan Yin;Yin-Fang Yan;Yu-Ling Wang;Xiao-Fei Shang;Ying-Qian Liu;Zhong-Min Zhao;Jing-Wen Peng;Hua Liu |
| 19 | Anti-phytopathogenic activity and the possible mechanisms of action of isoquinoline alkaloid sanguinarine | 期刊论文 | Zhong-min Zhao;Xiao-fei Shang;Raymond Kobla Lawoe;Ying-qian Liu;Rui Zhou;Yu Sun;Yin-fang Yan;Jun-cai Li;Guan-zhou Yang;Cheng-jie Yang |
| 20 | Discovery of Novel Antifungal Quinoline Derivatives with Acylhydrazide as a Promising Pharmacophore | 期刊论文 | Yu-Dong Yang;Ying-Hui He;Kun-Yuan Ma;Hu Li;Zhi-Jun Zhang;Yu Sun;Yu-Ling Wang;Guan-Fang Hu;Ren-Xuan Wang;Ying-Qian Liu |
| 21 | Integrated Proteomics and Transcriptomics Analyses Reveals the Possible Antifungal Mechanism of an Indoloquinoline Alkaloid Neocryptolepine against Rhizoctonia solani | 期刊论文 | Xiao-Fei Shang;Li-Xia Dai;Zhi-Jun Zhang;Cheng-Jie Yang;Sha-Sha Du;Tian-Lin Wu;Ying-Hui He;Jia-Kai Zhu;Ying-Qian Liu;Yin-Fang Yan;Xiao-Lou Miao;Ji-Yu Zhang |
| 22 | Design, synthesis and biological evaluation of novel evodiamine and rutaecarpine derivatives against phytopathogenic fungi | 期刊论文 | Cheng-Jie Yang;Hai-xin Li;Jing-Ru Wang;Zhi-Jun Zhang;Tian-Lin Wu;Ying-Qian Liu;Chen Tang;Qing-Ru Chu;Sha-Sha Du;Ying-Hui He |
| 23 | 一种骆驼宁碱类似物在防治农业植物病害中的应用 | 专利 | 刘映前;王仁轩;杜莎莎;吴天琳;贺颖慧;张智军;赵文斌;杨程杰 |
| 24 | 8-羟基喹啉锰、镁及镍配合物在制备农用杀菌剂中的用途 | 专利 | 刘映前;尹晓丹;黄晓玲;孙钰;彭静文;赵中敏;刘华 |
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