DNA硫修饰及其限制系统的遗传生理机制研究

31130068
2011
C0602.基因表达及非编码序列调控
邓子新
重点项目
教授
上海交通大学
320万元
甲基化;限制系统;转录组芯片;DNA磷硫酰化;蛋白结构和功能
2012-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Structure of the N-glycosidase MilB in complex with hydroxymethyl CMP reveals its Arg23 specifically recognizes the substrate and controls its entry. 期刊论文 Liu, Guang|Han, Tiesheng|Deng, Zixin|He, Xinyi|
2 Regulation of DNA phosphorothioate modification in Salmonella enterica by DndB 期刊论文 Wang, Yajie|Liu, Xiaoyun|Chen, Shi|Wang, Lianrong|
3 DNA phosphorothioate modifications influence the global transcriptional response and protect DNA from double-stranded breaks 期刊论文 Zixin Deng|Dequan Liang|Shi Chen|Lianrong Wang|
4 Phosphorothioate DNA as an antioxidant in bacteria 期刊论文 You, Delin|Zhou, Xiufen|Deng, Zixin|Wang, Zhijun|
5 DNA分子骨架上硫原子的发现 奖励 邓子新|王连荣|
6 沙门氏菌硫修饰基因dptC的克隆表达与分离纯化 期刊论文 周秀芬|汪志军|邓子新|梁晶丹|
7 A Novel Target of IscS in Escherichia coli: Participating in DNA Phosphorothioation 期刊论文 Zhou Xiufen|Wang Zhijun|Deng Zixin|Liang Jindan|
8 Crystallization and preliminary X-ray analysis of the type IV restriction endonuclease ScoMcrA from Streptomyces coelicolor, which cleaves both Dcm-methylated DNA and phosphorothioated DNA. 期刊论文 Zhao, Gong|Deng, Zixin|Wu, Geng|He, Xinyi|
9 Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences 期刊论文 You, Delin|Wang, Lianrong|Chen, Shi|Dedon, Peter C.|
10 Pathological phenotypes and in vivo DNA cleavage by unrestrained activity of a phosphorothioate- based restriction system in Salmonella 期刊论文 Zheng, Xiaoqing|Deng, Zixin|Dedon, Peter C.|You, Delin|
11 何梁何利科学与技术进步奖 奖励 邓子新|
12 Interactions of Dnd proteins involved in bacterial DNA phosphorothioate modification. 期刊论文 Xiong, Wei|Zhao, Gong|Yu, Hao|He, Xinyi|
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