生理和病理状态中心肌蛋白troponin基因的调控

31271218
2012
C1101.循环与血液生理
黄旭培
面上项目
教授
重庆医科大学
72万元
基因调控;心脏发育;心力衰竭;心肌肥厚;肌钙蛋白
2013-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Abnormal splicing in the N-terminal variable region of cardiac troponin T impairs systolic function of the heart with preserved Frank-Starling compensation. 期刊论文 Chen, Guozhen|Nan, Changlong|Huang, Xupei|Jin, Jian-Ping|
2 Restrictive cardiomyopathy mutations demonstrate functions of the C-terminal end-segment of troponin I. 期刊论文 Akhter, Shirin|Bueltmann, Kenneth Jr|Huang, Xupei|Jin, J-P|
3 Inhibition of histone H3K9 acetylation by anacardic acid can correct the over-expression of Gata4 in the hearts of fetal mice exposed to alcohol during pregnancy. 期刊论文 Zhao, Wei-An|Zheng, Min|Liu, Ling-Juan|Tian, Jie|
4 Troponin mutation caused diastolic dysfunction and experimental treatment in transgenic mice with cardiomyopathy 期刊论文 Xu Y|J. Tian|X.P. Huang|
5 estricitve cardiomyopathy caused by troponinmutations: application of disease animal models in translational studies 期刊论文 Wen Shen|Junjun Quan|Xu Pei Huang|Jie Tian|
6 Alcohol exposure increases the expression of cardiac transcription factors through ERK1/2-mediated histone3 hyperacetylation in H9c2 cells. 期刊论文 Liu, Lingjuan|Huang, Xupei|Liu, Zhenguo|Tian, Jie|
7 Anacardic acid inhibits histone acetylases and attenuates alcohol induced cardiac hypertrophy in developing murine hearts 期刊论文 Weian Zhao|Jing Zhu|Xupei Huang|Jie Tian|
8 Curcumin-mediated cardiac defects in mouse is associated with a reduced histone H3 acetylation and reduced expression of cardiac transcription factors. 期刊论文 Zhu, Jing|Lu, Tiewei|Huang, Xupei|Tian, Jie|
9 Calcium desensitizer catechin reverses diastolic dysfunction in mice with restrictive cardiomyopathy 期刊论文 Pierre-Yves Jean-Charles|Cecile Getfield|Xiaoqing Wang|Xupei Huang|
10 Suberoylanilide Hydroxamic Acid Restores Estrogen Reduced-cTnI Expression in Neonatal Hearts of Mice 期刊论文 Xiaomei Luo|Qianlu Xing|Huichao Sun|Xu Pei Huang|
11 Diastolic dysfunction and cardiac troponin Idecrease in aging hearts 期刊论文 Z. Zhang|W. Shen|Xu Pei Huang|J. Tian|
12 Green tea extract catechin improves internalcardiac muscle relaxation in RCM mice. 期刊论文 Changlong Nan|Wen Shen|Yimin Hua|Xu Pei Huang|
13 Dose-dependent diastolic dysfunction and early death in a mouse model with cardiac troponin mutations. 期刊论文 Tian, Jie|Jin, J-P|Gelb, Ira J|Huang, Xupei|
14 Epigenetic regulation of cardiac myofibril gene expression during heart development. 期刊论文 Zhu, Jing|Nan, Changlong|Huang, Xupei|Tian, Jie|
15 DNA methylation regulates mouse cardiac myofibril gene expression during heart development. 期刊论文 Zhu, Jing|Nan, Changlong|Huang, Xupei|Tian, Jie|
16 Inhibition of histone H3K9 acetylation by anacardic acid can correct the over-expression of Gata4 in the hearts of fetal mice exposed to alcohol during pregnancy. 期刊论文 Zhao, Wei-An|Zheng, Min|Liu, Ling-Juan|Tian, Jie|
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