组蛋白H3Lys4甲基化的建立、维持和调控NF-κB信号途径的分子机制研究

91019013
2010
C0603.表观遗传调控
吴旻
重大研究计划
教授
武汉大学
60万元
基因转录调控;NF-κB;MLL1;组蛋白修饰;H3Lys4甲基化
2011-01-01到2013-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation 期刊论文 Hui Wang|Jin Liu|Yu Deng|Hong Cao|Dan Xua|Fenglong Cu|Youying Lei|Jacques Magdalou|Min Wu|
2 Inhibition of cancer cell proliferation by 5-fluoro-2’-deoxycytidine, a DNA methylation inhibitor, through activation of the DNA damage response pathway 期刊论文 Quanyi Zhao|Jiadong Fan|Wei Hong|Lianyun Li|Min Wu|
3 MLL1, a H3K4 methyltransferase, regulates the TNFa-stimulated activation of genes downstream of NF-kB 期刊论文 Min Wu|Kun Zhu|Shangze Li|Yifang Liao|Runlei Du|Xiaodong Zhang|Hong-Bing Shu|An-Yuan Guo|Lianyun Li|
4 Crosstalk between NSL histone functions in pomoting histone H3K4 di-methylation activity by MLL/SET complexes 期刊论文 Jingji Jin|Jiaming Su|Fei Wang|Da Liu|Jian Ding|Yang Yang|Joan W. Conaway|Ronald C. Conaway|Lingling Cao|
5 组蛋白H3K4甲基化酶对转录因子NF-kappaB下游靶基因表达的调控机制 会议论文 王翔|朱坤|李尚泽|杜润蕾|张晓东|舒红兵|李联运|吴旻|
6 Polycomb group genes as the key regulators in gene silencing 期刊论文 Shuaikun Su|Min Zhang|Lianyun Li|吴旻|
7 MLL1/WDR5 complex in leukemogenesis and epigenetic regulation 期刊论文 Wu, Min|Shu, Hong-Bing|
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