茉莉酸及其衍生物标准品的合成及在植物激素成分分析和作用机理研究中的应用

91017005
2010
C0206.植物激素与生长调节物质
周海兵
重大研究计划
教授
武汉大学
60万元
多样性化学合成;茉莉酸类化合物;成分分析;构效关系;植物调控机理研究
2011-01-01到2013-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Enhanced efficiency of recyclable C-3-symmetric cinchonine-squaramides in the asymmetric Friedel-Crafts reaction of indoles with alkyl trifluoropyruvate 期刊论文 Xin Han|Bin Liu|Hai-Bing Zhou|Chune Dong|
2 An expedient approach to highly enantioenriched cyclic nitrones mediated by robust and recoverable C-3-symmetric cinchonine-squaramide catalysts 期刊论文 Wu, Xiangfei|Min, Chang|Zhou, Hai-Bing|Dong, Chune|
3 Design, synthesis and biological evaluation of novel estrogen-derived steroid metal complexes 期刊论文 Yuntai, Kangxiang|Huang, Jian|Lan, Xiaoli|Zhou, Hai-Bing|
4 C-3-Symmetrical Cinchonine-Squaramide as New Highly Efficient, and Recyclable Organocatalyst for Enantioselective Michael Addition 期刊论文 Min, Chang|Han, Xin|Liao, Zongquan|Wu, Xiangfei|Zhou, Hai-Bing|Dong, Chune|
5 Discovery of novel SERMs with a ferrocenyl entity based on the oxabicyclo[2.2.1]heptene scaffold and evaluation of their antiproliferative effects in breast cancer cells 期刊论文 Ren, Wenming|Dong, Chune|Huang, Jian|Zhou, Hai-Bing|
6 Novel Bifunctional Ligands for Dual Regulation of Estrogen Receptor 会议论文 周海兵|
7 Bicyclic core estrogens as full antagonists: synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfonamides 期刊论文 Dong, Chune|Katzenellenbogen, John A.|Nettles, Kendall W.|Zhou, Hai-Bing|
8 Study on the dual regulation of estrogen receptor with small molecules. 会议论文 周海兵|
9 Thiophene-Core Estrogen Receptor Ligands Having Superagonist Activity 期刊论文 Carlson, Kathryn E.|Katzenellenbogen, John A.|Nettles, Kendall W.|Zhou, Hai-Bing|
10 雌激素受体的小分子双重调控及相关药物研究 会议论文 周海兵|
11 Chiral squaramide as multiple H-bond donor organocatalysts for the asymmetric Michael addition of 1,3-dicarbonyl compounds to nitroolefins 期刊论文 Ze Dong|Guofu Guo|Hai-Bing Zhou|Chune Dong|
12 Novel bifunctional chiral squaramide-amine catalysts for highly enantioselective addition of mono-and diketones to nitroalkenes 期刊论文 C.|Z.|Jin|X.|Wang|P.|Min|C.|Zhang|
13 Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters 期刊论文 Deng, Zixin|He, Maomao|Wang, Yaya|Zhai, Linhui|Cui, Yongbo|Li, Yangyan|Li, Yan|Zhou, Haibing|Hong, Xuechuan|
14 Diversity-Oriented Synthesis Leads to an Effective Class of Novel Selective Estrogen Receptor Modulators (SERMs) 会议论文 周海兵|
15 Modular synthesis and biological evaluation of novel estrogen receptor ligands based on a 7-thia-bicyclo[2.2.1]hept-2-ene-7-oxide or 7-oxabicyclo[2.2.1]hept-5-ene skeleton 会议论文 Zhou, Haibing|Zheng, Yangfan|Wang, Pengcheng|Katzenellenbogen, John A.|Nettles, Kendall W.|
16 A simple and straightforward approach toward selective C = C bond reduction by hydrazine 期刊论文 Wang, Jianmin|Hong, Xuechuan|Zhou, Hai-Bing|Dong, Chune|
17 Highly enantioselective Michael addition of 1,3-dicarbonyl compounds to nitroalkenes catalyzed by designer chiral BINOL–quinine–squaramide: efficient access to optically active nitro-alkanes and their isoxazole derivatives 期刊论文 Ze Dong|Hao Lv|Hai-Bing Zhou|Chune Dong|
18 Enantioselective inhibition of reverse transcriptase (RT) of HIV-1 by non-racemic indole-based trifluoropropanoates developed by asymmetric catalysis using recyclable organocatalysts. Xin Han, Wenjie Ouyang, Bin Liu, Wei Wang*, Po Tien, Shuwen Wu*, H 期刊论文 Xin Han|Wenjie Ouyang|Bin Liu|Wei Wang|Po Tien|Shuwen Wu|Hai-Bing Zhou|
19 Identification and Structure-Activity Relationships of a Novel Series of Estrogen Receptor Ligands Based on 7-Thiabicyclo[2.2.1]hept-2-ene-7-oxide 期刊论文 Dong, Chune|Katzenellenbogen, John A.|Nettles, Kendall W.|Zhou, Hai-Bing|
20 A novel C(3)-symmetric prolinol-squaramide catalyst for the asymmetric reduction of ketones by borane 期刊论文 Wu X.-F.|Min C.|Nyamzundui E.|Zhou H.-B.|Dong C.|
21 Novel bivalent ligands for the estrogen receptor: Design, synthesis and biological study 会议论文 周海兵|
22 Hai-Bing Zhou*. Progress on selective estrogen receptor modulators with novel scaffolds and dual regulation activities. 会议论文 周海兵|
23 Development of Selective Estrogen Receptor Modulator (SERM)-Like Activity Through an Indirect Mechanism of Estrogen Receptor Antagonism: Defining the Binding Mode of 7-Oxabicyclo[2.2.1]hept-5-ene Scaffold Core Ligands 期刊论文 Dong, Chune|Katzenellenbogen, John A.|Nettles, Kendall W.|Zhou, Hai-Bing|
24 Hai-Bing Zhou, Progress in discovery of new selective estrogen receptor modulators (SERMs) based on novel structural templates 会议论文 周海兵|
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