抗DNA病毒天然免疫信号转导的翻译后修饰调节

31630045
2016
C0702.细胞信号转导
舒红兵
重点项目
教授
武汉大学
289万元
接头蛋白;sumo化;病毒;泛素化;天然免疫
2017-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Regulation of TRIF-mediated innate immune response by K27-linked polyubiquitination and deubiquitination 期刊论文 Wu Xin;Lei Cao-Qi;Xia Tian;Zhong Xuan;Yang Qing;Shu Hong-Bing
2 TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses 期刊论文 Yang Qing;Liu Tian-Tian;Lin Heng;Zhang Man;Wei Jin;Luo Wei-Wei;Hu Yun-Hong;Zhong Bo;Hu Ming-Ming;Shu Hong-Bing
3 SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA 期刊论文 Wei Jin;Lian Huan;Guo Wei;Chen Yun-Da;Zhang Xia-Nan;Zang Ru;Zhong Li;Yang Qing;Hu Ming-Ming;Luo Wei-Wei;Shu Hong-Bing;Li Shu
4 Human Cytomegalovirus Tegument Protein UL82 Inhibits STING-Mediated Signaling to Evade Antiviral Immunity 期刊论文 Fu Yu-Zhi;Su Shan;Gao Yi-Qun;Wang Pei-Pei;Huang Zhe-Fu;Hu Ming-Ming;Luo Wei-Wei;Li Shu;Luo Min-Hua;Wang Yan-Yi;Shu Hong-Bing
5 CSK promotes innate immune response to DNA virus by phosphorylating MITA 期刊论文 Gao Peng;Hu Ming-Ming;Shu Hong-Bing
6 SNX8 mediates IFN gamma-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes 期刊论文 Wei Jin;Guo Wei;Lian Huan;Yang Qing;Lin Heng;Li Shu;Shu Hong-Bing
7 The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors 期刊论文 Lian Huan;Zang Ru;Wei Jin;Ye Wen;Hu Ming-Ming;Chen Yun-Da;Zhang Xia-Nan;Guo Yi;Lei Cao-Qi;Yang Qing;Luo Wei-Wei;Li Shu;Shu Hong-Bing
8 The Membrane-Associated MARCH E3 Ligase Family: Emerging Roles in Immune Regulation 期刊论文 Lin Heng;Li Shu;Shu Hong-Bing
9 Innate Immune Response to Cytoplasmic DNA: Mechanisms and Diseases. 期刊论文 Hu Ming-Ming;Shu Hong-Bing
10 Cytoplasmic Mechanisms of Recognition and Defense of Microbial Nucleic Acids 期刊论文 Hu Ming-Ming;Shu Hong-Bing
11 Mitotic inactivation of the cGAS‒MITA/STING pathways 期刊论文 Zhong Li;Shu Hong-Bing
12 ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response 期刊论文 Lian Huan;Wei Jin;Zang Ru;Ye Wen;Yang Qing;Zhang Xia-Nan;Chen Yun-Da;Fu Yu-Zhi;Hu Ming-Ming;Lei Cao-Qi;Luo Wei-Wei;Li Shu;Shu Hong-Bing
13 PCBP1 modulates the innate immune response by facilitating the binding of cGAS to DNA. 期刊论文 Liao Chen-Yang;Lei Cao-Qi;Shu Hong-Bing
14 The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by antagonizing RNA sensing of RIG-I-like receptors 期刊论文 Cao Pan;Luo Wei-Wei;Li Chen;Tong Zhen;Zheng Zhou-Qin;Zhou Lu;Xiong Yong;Li Shu
15 ZDHHC11 modulates innate immune response to DNA virus by mediating MITA-IRF3 association. 期刊论文 Liu Ying;Zhou Qian;Zhong Li;Lin Heng;Hu Ming-Ming;Zhou Yan;Shu Hong-Bing;Li Shu
16 MARCH3 attenuates IL-1 beta-triggered inflammation by mediating K48-linked polyubiquitination and degradation of IL-1RI 期刊论文 Lin Heng;Gao Deng;Hu Ming-Ming;Zhang Man;Wu Xiao-Xia;Feng Lu;Xu Wen-Hua;Yang Qing;Zhong Xuan;Wei Jin;Xu Zhi-Sheng;Zhang Hong-Xia;Song Ze-Min;Zhou Qian;Ye Wen;Liu Ying;Li Shu;Shu Hong-Bing
17 PKACs attenuate innate antiviral response by phosphorylating VISA and priming it for MARCH5-mediated degradation 期刊论文 Yan Bing-Ru;Zhou Lu;Hu Ming-Ming;Li Mi;Lin Heng;Yang Yan;Wang Yan-Yi;Shu Hong-Bing
18 mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis 期刊论文 Liu Rui;Zeng Lin-Wen;Gong Rong;Yuan Fanen;Shu Hong-Bing;Li Shu
19 USP19 Inhibits TNF-alpha- and IL-1 beta-Triggered NF-kappa B Activation by Deubiquitinating TAK1 期刊论文 Lei Cao Qi;Wu Xin;Zhong Xuan;Jiang Lu;Zhong Bo;Shu Hong-Bing
20 Regulator of TGR5 signaling as immunomodulatory agent 专利 舒红兵;胡明明
21 Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5 期刊论文 Hu Ming-Ming;Liao Chen-Yang;Yang Qing;Xie Xue-Qin;Shu Hong-Bing
22 PTPN1/2-mediated dephosphorylation of MITA/STING promotes its 20S proteasomal degradation and attenuates innate antiviral response 期刊论文 Xia Tian;Yi Xue-Mei;Wu Xin;Shang Jun;Shu Hong-Bing
23 The zinc-finger protein ZFYVE1 modulates TLR3-mediated signaling by facilitating TLR3 ligand binding 期刊论文 Zhong Xuan;Feng Lu;Xu Wen-Hua;Wu Xin;Ding Yi-Di;Zhou Yan;Lei Cao-Qi;Shu Hong-Bing
24 SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA. 期刊论文 Guo Wei;Wei Jin;Zhong Xuan;Zang Ru;Lian Huan;Hu Ming-Ming;Li Shu;Shu Hong-Bing;Yang Qing
25 The membrane-associated E3 ubiquitin ligase MARCH3 downregulates the IL-6 receptor and suppresses colitis-associated carcinogenesis 期刊论文 Lin Heng;Feng Lu;Cui Kai-Sa;Zeng Lin-Wen;Gao Deng;Zhang Long-Xiang;Xu Wen-Hua;Sun Yu-Hao;Shu Hong-Bing;Li Shu
26 KAT5 acetylates cGAS to promote innate immune response to DNA virus 期刊论文 Song Ze-Min;Lin Heng;Yi Xue-Mei;Guo Wei;Hu Ming-Ming;Shu Hong-Bing
27 The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response 期刊论文 Li Chen;Feng Lu;Luo Wei-Wei;Lei Cao-Qi;Li Mi;Shu Hong-Bing
28 Dephosphorylation of cGAS by PPP6C impairs its substrate binding activity and innate antiviral response. 期刊论文 Li Mi;Shu Hong-Bing
29 Deciphering the pathways to antiviral innate immunity and inflammation. 期刊论文 Yang Qing;Shu Hong-Bing
30 Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis. 期刊论文 Zhong Li;Hu Ming-Ming;Bian Li-Jun;Liu Ying;Chen Qiang;Shu Hong-Bing
31 VRK2 is involved in the innate antiviral response by promoting mitostress-induced mtDNA release. 期刊论文 He Wen-Rui;Cao Li-Bo;Yang Yu-Lin;Hua Duo;Hu Ming-Ming;Shu Hong-Bing
32 ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response 期刊论文 Zhong Xuan;Feng Lu;Zang Ru;Lei Cao-Qi;Yang Qing;Shu Hong-Bing
33 Virus-induced accumulation of intracellular bile acids activates the TGR5-beta-arrestin-SRC axis to enable innate antiviral immunity 期刊论文 Hu Ming-Ming;He Wen-Rui;Gao Peng;Yang Qing;He Ke;Cao Li-Bo;Li Shu;Feng Yu-Qi;Shu Hong-Bing
34 ZCCHC3 modulates TLR3-mediated signaling by promoting recruitment of TRIF to TLR3 期刊论文 Zang Ru;Lian Huan;Zhong Xuan;Yang Qing;Shu Hong-Bing
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