WWP2调节TLR3信号转导的机制
31170792
2011
C0503.细胞感应与环境生物物理
王延轶
面上项目
研究员
武汉大学
65万元
TRIF;泛素化;抗病毒天然免疫;信号转导;WWP2
2012-01-01到2015-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | MITA/STING: a central and multifaceted mediator in innate immune response | 期刊论文 | Ran Y|Shu HB|Wang YY| |
| 2 | The E3 ligase WWP2 negatively regulates TLR3-mediated innate immune response by targeting TRIF for ubiquitination and degradation | 期刊论文 | Yan B|Jin Y|Shu HB|Wang YY*| |
| 3 | Heat shock cognate 71 (HSC71) regulates cellular antiviral response by impairing formation of VISA aggregates | 期刊论文 | Zhou Q|Li S|Shu HB|Wang YY*| |
| 4 | Innate immune responses to DNA viruses | 期刊论文 | Nie Y|Wang YY*| |
| 5 | Autoubiquitination of TRIM26 links TBK1 to NEMO inRLR-mediated innate antiviral immune response | 期刊论文 | 王延轶| |
| 6 | The E3 ubiquitin ligase MIB1 negatively regulates basal IkappaBalpha level and modulates NF-kappaB activation | 期刊论文 | Li Y|Zhang XD|Shu HB*|Wang YY*| |
| 7 | Tripartite motif 8 (TRIM8) modulates TNFalpha- and IL-1beta-triggered NF-kappaB activation by targeting TAK1 for K63-linked polyubiquitination | 期刊论文 | Li C|Ran Y|Shu HB*|Wang YY*| |
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